Results 211 to 220 of about 141,427 (302)

Pharmacological Incongruity of Lacosamide in the Management of Delirium Complicated by Ileus

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
Delirium involves neurotransmitter imbalances and disrupted neural networks. Although lacosamide may theoretically treat delirium by reducing neuronal hyperexcitability via sodium channel modulation, clinical evidence is lacking. Sodium channels in the enteric nervous system mean lacosamide can cause gastrointestinal dysmotility independent of ...
Takahiko Nagamine
wiley   +1 more source

Neural Innervation of Tumors: Mechanisms, Hallmarks, and Therapeutic Opportunities. [PDF]

Cancers (Basel)
Cassim S, Montemagno C.
europepmc   +1 more source

The importance of longitudinal evaluation using DAT‐SPECT in organophosphate‐induced toxic parkinsonism

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
We performed longitudinal evaluation using magnetic resonance imaging (MRI) and dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) in a case of organophosphate‐induced toxic parkinsonism. Fluid‐attenuated inversion recovery (FLAIR) images showed bilateral striatal hyperintensity in the acute phase, followed by reduction of ...
Shuhei Nakao, Yoichiro Kogoh, Hideki Funahashi, Yusei Yanoma, Minako Azuma, Yasushi Ishida, Yoji Hirano   +6 more
wiley   +1 more source

Cardiac endogenous transmitter system: molecular features, functions, and clinical implications. [PDF]

Eur Heart J
Xie D, Liang D, Zhou L, Liu Y, Chen YH.
europepmc   +1 more source

The Antipsychotic Aripiprazole Induces Cytotoxicity in Bladder Cancer Cells While Preserving Urothelial and Bladder Function

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
Current bladder cancer therapies can cause toxicity and bladder dysfunction. Brief intravesical‐like aripiprazole exposure reduced bladder cancer cell viability and was associated with redox stress and caspase‐3 activation, while ex vivo findings suggested preserved bladder structure and function, warranting further investigation as a potential ...
Liam A. O'Callaghan, Katie Powell, Russ Chess‐Williams, Catherine McDermott   +3 more
wiley   +1 more source

From dopamine to muscarine: xanomeline-trospium (KarXT) as a novel direction in the psychopharmacotherapy of schizophrenia. [PDF]

Front Pharmacol
Żełabowski K, Pichowicz W, Dembowska J, Szwajkowski M, Mykhailova D, Wurm G, Biedka K, Błaszczyk K, Piotrowski P.   +8 more
europepmc   +1 more source

Bidirectional genetic and phenotypic links between smoking and striatal iron content involving dopaminergic and inflammatory pathways

Addiction, Volume 121, Issue 6, Page 1580-1593, June 2026.
Abstract Background and aims Tobacco smoking is a major risk factor for cardiovascular and lung diseases. A better understanding of its neurobiological underpinnings will benefit the prevention of smoking‐related illnesses and mortality. Previous studies link smoking to increased iron concentration in the striatum, a central component of the brain's ...
Olga Trofimova, Ilaria Iuliani, Sven Bergmann   +2 more
wiley   +1 more source

Heartfelt intervention: A role for PVN oxytocin neurons in the prediabetic heart

The Journal of Physiology, EarlyView.
Grace K. Nielsen, Reesa M. Wilcox, Han‐Jun Wang   +2 more
wiley   +1 more source

Hippocampal subfield differences in people with and without recreational ketamine use: Insights from multi‐modal neuroimaging

Addiction, Volume 121, Issue 6, Page 1541-1556, June 2026.
Abstract Background and aims Recreational ketamine use has increased globally and is associated with psychiatric and cognitive concerns. The hippocampus in preclinical models shows damage and working‐memory disruption with repeated dosing. However, whether specific hippocampal subregions may differ in people with chronic ketamine use remains unclear ...
Yi‐Hsuan Liu, Chia‐Chun Hung, Marc N. Potenza, Kun‐Hsien Chou, Pei‐Lin Lee, Chu‐Chung Huang, Chiang‐Shan R. Li, Tony Szu‐Hsien Lee, Ching‐Po Lin   +8 more
wiley   +1 more source

Alternative Pathways of Acetylcholine Release in the Colon: Role of High-Affinity Choline Transporters. [PDF]

Neurogastroenterol Motil
Martinez-Daunis A, Yordanova B, Traserra S, Vergara P, Jimenez M.   +4 more
europepmc   +1 more source