Results 1 to 10 of about 131,032 (117)
The central cholinergic system as a therapeutic target in Parkinson's disease [PDF]
Journal of Parkinson’s DiseaseThe central cholinergic system plays a crucial role in neural communication and physiological regulation, mediated by acetylcholine (ACh) and cholinergic receptors in the central nervous system (CNS). In this review, we explore the extensive distribution
Sean J Miller +4 more
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Cholinergic System and Its Therapeutic Importance in Inflammation and Autoimmunity
Frontiers in Immunology, 2021 Neurological and immunological signals constitute an extensive regulatory network in our body that maintains physiology and homeostasis. The cholinergic system plays a significant role in neuroimmune communication, transmitting information regarding the ...
Namrita Halder, Girdhari Lal
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Characterization of social behavior in young and middle-aged ChAT-IRES-Cre mouse.
PLoS ONE, 2022 The cholinergic system is an important modulator of brain processes. It contributes to the regulation of several cognitive functions and emotional states, hence altering behaviors.
Cyril Lhopitallier +6 more
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Cellular birthdate predicts laminar and regional cholinergic projection topography in the forebrain
eLife, 2020 The basal forebrain cholinergic system projects broadly throughout the cortex and constitutes a critical source of neuromodulation for arousal and attention. Traditionally, this system was thought to function diffusely.
Kathryn C Allaway +7 more
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Scientific Reports, 2021 Social behaviour is a complex construct that is reported to include several components of social approach, interaction and recognition memory. Alzheimer’s disease (AD) is mainly characterized by progressive dementia and is accompanied by cognitive ...
Kana Okada +5 more
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ACETYLCHOLINE AND ITS SYNTHESIZING ENZYME CHOLINE ACETYLTRANSPHERASE IN THE ENTERIC NERVOUS SYSTEM [PDF]
Journal of IMAB, 2022 The enteric nervous system is the largest and most complex division of the peripheral nervous system. Located in the wall of the gastrointestinal tract, it is a regulatory and coordination unit of the nervous system.
Desislava M. Marinova +5 more
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Acetylcholine and spinal locomotor networks: The insider
Physiological Reports, 2021 This article aims to review studies that have investigated the role of neurons that use the transmitter acetylcholine (ACh) in controlling the operation of locomotor neural networks within the spinal cord. This cholinergic system has the particularity of
Théo Mille +3 more
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PET Imaging of Perceptual Learning-Induced Changes in the Aged Rodent Cholinergic System
Frontiers in Neuroscience, 2020 The cholinergic system enhances attention and gates plasticity, making it a major regulator of adult learning. With aging, however, progressive degeneration of the cholinergic system impairs both the acquisition of new skills and functional recovery ...
J. Miguel Cisneros-Franco +16 more
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Frontiers in Pharmacology, 2018 Nicotinic acetylcholine receptors (nAChRs) expressed on the cell plasma membrane are ligand-gated ion channels mediating fast synaptic transmission, regulating neurotransmitter and cytokine release and supporting the viability of many cell types.
Kateryna Uspenska +6 more
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Central Cholinergic Nervous System and Cholinergic Agents
Acta Medica, 1998 Central cholinergic nervous system play important role in many physiological and behavioral functions in humans. The activity of the cholinergic nervous system depends upon the production and fate of acetylcholine and all compounds influenced its ...
Jiří Patočka
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