Results 21 to 30 of about 131,181 (262)
Acetylcholine modulates the temporal dynamics of human theta oscillations during memory
Nature Communications, 2023 The cholinergic system is essential for memory. While degradation of cholinergic pathways characterizes memory-related disorders such as Alzheimer’s disease, the neurophysiological mechanisms linking the cholinergic system to human memory remain unknown.
Tamara Gedankien +6 more
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Neurobiology of Disease, 2011 Vascular cognitive impairment has been related to dysfunction of the central cholinergic system. Studies exploring the putative relationship between vascular cognitive impairment and cholinergic dysfunction have largely been aimed at symptomatic ...
Erik I. Hoff +6 more
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Potential revival of cholinesterase inhibitors as drugs in veterinary medicine
Frontiers in Veterinary Science, 2023 The cholinergic system is involved in the regulation of all organ systems and has acetylcholine (ACh) as almost its only neurotransmitter. Any substance is called cholinergic if it can alter the action of acetylcholine. Cholinesterases (ChEs) are enzymes
Neža Žnidaršič +3 more
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66108 Central Cholinergic Synapse Formation in Optimized Primary Septal “Hippocampal Co” cultures
Journal of Clinical and Translational Science, 2021 IMPACT: Optimization of primary septal-hippocampal co-cultures facilitates studying central cholinergic synapse formation and dysfunction OBJECTIVES/GOALS: Septal cholinergic innervation to the hippocampus is critical for normal learning and memory and ...
Sarra Djemil +4 more
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Complete morphologies of basal forebrain cholinergic neurons in the mouse
eLife, 2014 The basal forebrain cholinergic system modulates neuronal excitability and vascular tone throughout the cerebral cortex and hippocampus. This system is severely affected in Alzheimer's disease (AD), and drug treatment to enhance cholinergic signaling is ...
Hao Wu, John Williams, Jeremy Nathans
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Cell Reports, 2018 Summary: The cholinergic neurons of the basal forebrain (BF) provide virtually all of the brain’s cortical and amygdalar cholinergic input. They are particularly vulnerable to neuropathology in early Alzheimer’s disease (AD) and may trigger the emergence
Taylor W. Schmitz +4 more
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European Journal of Histochemistry, 2021 Several cholinergic regions have been detected in the brainstem of mammals. In general, these regions are constant among different species, and the nuclear complement is maintained in animals belonging to the same order.
Pilar Marcos, Rafael Coveñas
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Frontiers in Immunology, 2017 Degeneration of central cholinergic neurons impairs memory, and enhancement of cholinergic synapses improves cognitive processes. Cholinergic signaling is also anti-inflammatory, and neuroinflammation is increasingly linked to adverse memory, especially ...
Sara V. Maurer, Christina L. Williams
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Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias +3 more
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Boosting visual cortex function and plasticity with acetylcholine to enhance visual perception
Frontiers in Systems Neuroscience, 2014 The cholinergic system is a potent neuromodulatory system that plays critical roles in cortical plasticity, attention and learning. In this review, we propose that the cellular effects of acetylcholine in the primary visual cortex during the processing ...
Jun-Il eKang +3 more
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