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Basal forebrain atrophy in frontotemporal dementia [PDF]
NeuroImage: Clinical, 2020 Background: The basal forebrain is a subcortical structure that plays an important role in learning, attention, and memory. Despite the known subcortical involvement in frontotemporal dementia (FTD), there is little research into the role of the basal ...
Rhian S. Convery +8 more
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The role of the basal forebrain in general anesthesia
Ibrain, 2023 The basal forebrain is a group of nerve nuclei on the ventral side of the ventral ganglion, composed of γ‐aminobutyric acid neurons, glutamatergic neurons, cholinergic neurons, and orexigenic neurons.
Yi‐Ting Peng +2 more
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Thalamus not basal forebrain is atrophied in non‐demented PSEN1 E280A carriers [PDF]
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease MonitoringINTRODUCTION A previous study of non‐demented presenilin‐1 (PSEN1) E280A carriers found basal forebrain and hippocampus, but not the thalamus, to be preserved.
Stefan Teipel +6 more
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Disrupted basal forebrain-cortical connectivity in amnestic mild cognitive impairment: unveiling circuit-level links to cognitive decline [PDF]
Frontiers in NeurologyBackgroundAmnestic Mild Cognitive Impairment (aMCI) is a transitional stage between normal individuals and dementia. The basal forebrain is a key subcortical hub involved in memory-related cortico-subcortical networks.MethodsA total of 66 aMCI patients ...
Rong-Rong Huang +8 more
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Predicting longitudinal basal forebrain volume in the Alzheimer’s disease spectrum: the role of sex and ApoE epsilon 4 genotype [PDF]
Frontiers in NeuroscienceIntroductionImaging studies showed early atrophy of the cholinergic basal forebrain (BF) already at prodromal stages of sporadic Alzheimer’s disease (AD).
Alice Grazia +28 more
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Adolescent adversity persistently induces proinflammatory HMGB1 signaling and disrupts the basal forebrain cholinergic system in female rats [PDF]
Neurobiology of StressAdolescence is a critical period of neurodevelopment characterized by heightened neuroplasticity and refinement of executive functioning and cognition.
Hayley Ross +8 more
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Frontiers in Cellular Neuroscience, 2021 Sensory perception underlies how we internalize and interact with the external world. In order to adapt to changing circumstances and interpret signals in a variety of contexts, sensation needs to be reliable, but perception of sensory input needs to be ...
Elizabeth Hanson +2 more
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Frontiers in Neural Circuits, 2022 The basal forebrain is one of the three major brain circuits involved in episodic memory formation together with the hippocampus and the diencephalon. The dysfunction of each of these regions is known to cause anterograde amnesia.
Marian Tsanov
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Cognitive Deficits in Aging Related to Changes in Basal Forebrain Neuronal Activity
Cells, 2023 Aging is a physiological process accompanied by a decline in cognitive performance. The cholinergic neurons of the basal forebrain provide projections to the cortex that are directly engaged in many cognitive processes in mammals.
Irene Chaves-Coira +4 more
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Scientific Reports, 2021 We assessed the structure–function relationship of the human cholinergic system and hypothesized that structural measures are associated with short-latency sensory afferent inhibition (SAI), an electrophysiological measure of central cholinergic signal ...
Jessica Peter +7 more
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