Results 11 to 20 of about 526,321 (280)
Bisphenol-A Neurotoxic Effects on Basal Forebrain Cholinergic Neurons In Vitro and In Vivo
Biology, 2023 The widely used plasticizer bisphenol-A (BPA) is well-known for producing neurodegeneration and cognitive disorders, following acute and long-term exposure.
Andrea Flores +10 more
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The basal forebrain contributes to cue-based spatial navigation performance inAlzheimer’s disease [PDF]
Frontiers in Aging Neuroscience, 2015 The basal forebrain degenerates in Alzheimer’s disease (AD) and this process is believed to contribute to the cognitive decline observed in AD patients.
Georg M Kerbler +13 more
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Basal forebrain modulation of olfactory coding in vivo
International Journal of Psychological Research, 2023 Sensory perception is one of the most fundamental brain functions allowing individuals to properly interact and adapt to a constantly changing environment. This process requires the integration of bottom-up and top-down neuronal activity that is centrally mediated by the basal forebrain, a brain region that has been linked to a series of cognitive ...
Venegas, Juan Pablo +5 more
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Basal forebrain atrophy correlates with amyloid β burden in Alzheimer's disease [PDF]
NeuroImage: Clinical, 2015 The brains of patients suffering from Alzheimer's disease (AD) have three classical pathological hallmarks: amyloid-beta (Aβ) plaques, tau tangles, and neurodegeneration, including that of cholinergic neurons of the basal forebrain.
Georg M Kerbler +6 more
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Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology [PDF]
Nature Communications, 2016 Whether Alzheimer’s disease originates in basal forebrain or entorhinal cortex remains highly debated. Here the authors use structural magnetic resonance data from a longitudinal sample of participants stratified by cerebrospinal biomarker and clinical ...
Taylor W. Schmitz +2 more
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Basal Forebrain Cholinergic System and Memory [PDF]
, 2016 Basal forebrain cholinergic neurons constitute a way station for many ascending and descending pathways. These cholinergic neurons have a role in eliciting cortical activation and arousal. It is well established that they are mainly involved in cognitive processes requiring increased levels of arousal, attentive states and/or cortical activation with ...
Blake, Mariano Guillermo +1 more
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Task-Phase-Specific Dynamics of Basal Forebrain Neuronal Ensembles [PDF]
Frontiers in Systems Neuroscience, 2014 Cortically projecting basal forebrain neurons play a critical role in learning and attention, and their degeneration accompanies age-related impairments in cognition.
David eTingley +5 more
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Basal forebrain subcortical projections [PDF]
Brain Structure and Function, 2019 The basal forebrain (BF) contains at least three distinct populations of neurons (cholinergic, glutamatergic, and GABA-ergic) across its different regions (medial septum, diagonal band, magnocellular preoptic area, and substantia innominata). Much attention has focused on the BF's ascending projections to cortex, but less is known about descending ...
Lindsay J, Agostinelli +2 more
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Brain and Behavior, 2023 Introduction Regulation of brain‐derived neurotrophic factor (BDNF) in the basal forebrain ameliorates sleep deprivation‐induced fear memory impairments in rodents.
Tao Ma +9 more
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Adolescent binge ethanol-induced loss of basal forebrain cholinergic neurons and neuroimmune activation are prevented by exercise and indomethacin. [PDF]
PLoS ONE, 2018 Basal forebrain cholinergic neurons mature in adolescence coinciding with development of adult cognitive function. Preclinical studies using the rodent model of adolescent intermittent ethanol (AIE; 5.0 g/kg, i.g., 2-days on/2-days off from postnatal day
Ryan P Vetreno, Fulton T Crews
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