Results 31 to 40 of about 526,321 (280)

Basal Forebrain Volume, but Not Hippocampal Volume, Is a Predictor of Global Cognitive Decline in Patients With Alzheimer's Disease Treated With Cholinesterase Inhibitors

open access: yesFrontiers in Neurology, 2018
Background: Predicting the progression of cognitive decline in Alzheimer's disease (AD) is important for treatment selection and patient counseling. Structural MRI markers such as hippocampus or basal forebrain volumes might represent useful instruments ...
Stefan J. Teipel   +13 more
doaj   +1 more source

Role of neurotrophins in the adult and developing basal forebrain.

open access: yes, 1995
Role of neurotrophins in the adult and developing basal ...
Melanie Anne. Burke (7994828)
core   +6 more sources

Lesions of the basal forebrain cholinergic system in mice disrupt idiothetic navigation.

open access: yesPLoS ONE, 2013
Loss of integrity of the basal forebrain cholinergic neurons is a consistent feature of Alzheimer's disease, and measurement of basal forebrain degeneration by magnetic resonance imaging is emerging as a sensitive diagnostic marker for prodromal disease.
Adam S Hamlin   +4 more
doaj   +1 more source

Sensory perception drives food avoidance through excitatory basal forebrain circuits

open access: yeseLife, 2019
Appetite is driven by nutritional state, environmental cues, mood, and reward pathways. Environmental cues strongly influence feeding behavior, as they can dramatically induce or diminish the drive to consume food despite homeostatic state. Here, we have
Jay M Patel   +8 more
doaj   +1 more source

Adenosine and Sleep Homeostasis in the Basal Forebrain [PDF]

open access: yesThe Journal of Neuroscience, 2006
It is currently hypothesized that the drive to sleep is determined by the activity of the basal forebrain (BF) cholinergic neurons, which release adenosine (AD), perhaps because of increased metabolic activity associated with the neuronal discharge during waking, and the accumulating AD begins to inhibit these neurons so that sleep-active neurons can ...
Carlos, Blanco-Centurion   +7 more
openaire   +2 more sources

Lack of the murine homeobox gene Hesx1 leads to a posterior transformation of the anterior forebrain [PDF]

open access: yes, 2007
The homeobox gene Hesx1 is an essential repressor that is required within the anterior neural plate for normal forebrain development in mouse and humans. Combining genetic cell labelling and marker analyses, we demonstrate that the absence of Hesx1 leads
Andoniadou, CL   +27 more
core   +1 more source

Cellular birthdate predicts laminar and regional cholinergic projection topography in the forebrain

open access: yeseLife, 2020
The basal forebrain cholinergic system projects broadly throughout the cortex and constitutes a critical source of neuromodulation for arousal and attention. Traditionally, this system was thought to function diffusely.
Kathryn C Allaway   +7 more
doaj   +1 more source

Icariin Promotes Survival, Proliferation, and Differentiation of Neural Stem Cells In Vitro and in a Rat Model of Alzheimer’s Disease

open access: yesStem Cells International, 2021
Alzheimer’s disease (AD) involves the degeneration of cholinergic neurons in the basal forebrain. Neural stem cell (NSC) transplantation has emerged as a promising therapeutic approach for treating AD.
Denglei Ma   +5 more
doaj   +1 more source

Nerve Growth Factor Compromise in Down Syndrome

open access: yesFrontiers in Aging Neuroscience, 2021
The basal forebrain cholinergic system relies on trophic support by nerve growth factor (NGF) to maintain its phenotype and function. In Alzheimer’s disease (AD), basal forebrain cholinergic neurons (BFCNs) undergo progressive atrophy, suggesting a ...
Sonia Do Carmo   +5 more
doaj   +1 more source

Activity-dependent plasticity in visual forebrain areas of the zebra finch [PDF]

open access: yes, 1996
Rollenhagen A, Bischof H-J. Activity-dependent plasticity in visual forebrain areas of the zebra finch. Behavioural Brain Research.
Rollenhagen, Astrid   +3 more
core   +1 more source

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