Results 31 to 40 of about 526,321 (280)
Background: Predicting the progression of cognitive decline in Alzheimer's disease (AD) is important for treatment selection and patient counseling. Structural MRI markers such as hippocampus or basal forebrain volumes might represent useful instruments ...
Stefan J. Teipel +13 more
doaj +1 more source
Role of neurotrophins in the adult and developing basal forebrain.
Role of neurotrophins in the adult and developing basal ...
Melanie Anne. Burke (7994828)
core +6 more sources
Lesions of the basal forebrain cholinergic system in mice disrupt idiothetic navigation.
Loss of integrity of the basal forebrain cholinergic neurons is a consistent feature of Alzheimer's disease, and measurement of basal forebrain degeneration by magnetic resonance imaging is emerging as a sensitive diagnostic marker for prodromal disease.
Adam S Hamlin +4 more
doaj +1 more source
Sensory perception drives food avoidance through excitatory basal forebrain circuits
Appetite is driven by nutritional state, environmental cues, mood, and reward pathways. Environmental cues strongly influence feeding behavior, as they can dramatically induce or diminish the drive to consume food despite homeostatic state. Here, we have
Jay M Patel +8 more
doaj +1 more source
Adenosine and Sleep Homeostasis in the Basal Forebrain [PDF]
It is currently hypothesized that the drive to sleep is determined by the activity of the basal forebrain (BF) cholinergic neurons, which release adenosine (AD), perhaps because of increased metabolic activity associated with the neuronal discharge during waking, and the accumulating AD begins to inhibit these neurons so that sleep-active neurons can ...
Carlos, Blanco-Centurion +7 more
openaire +2 more sources
Lack of the murine homeobox gene Hesx1 leads to a posterior transformation of the anterior forebrain [PDF]
The homeobox gene Hesx1 is an essential repressor that is required within the anterior neural plate for normal forebrain development in mouse and humans. Combining genetic cell labelling and marker analyses, we demonstrate that the absence of Hesx1 leads
Andoniadou, CL +27 more
core +1 more source
Cellular birthdate predicts laminar and regional cholinergic projection topography in the forebrain
The basal forebrain cholinergic system projects broadly throughout the cortex and constitutes a critical source of neuromodulation for arousal and attention. Traditionally, this system was thought to function diffusely.
Kathryn C Allaway +7 more
doaj +1 more source
Alzheimer’s disease (AD) involves the degeneration of cholinergic neurons in the basal forebrain. Neural stem cell (NSC) transplantation has emerged as a promising therapeutic approach for treating AD.
Denglei Ma +5 more
doaj +1 more source
Nerve Growth Factor Compromise in Down Syndrome
The basal forebrain cholinergic system relies on trophic support by nerve growth factor (NGF) to maintain its phenotype and function. In Alzheimer’s disease (AD), basal forebrain cholinergic neurons (BFCNs) undergo progressive atrophy, suggesting a ...
Sonia Do Carmo +5 more
doaj +1 more source
Activity-dependent plasticity in visual forebrain areas of the zebra finch [PDF]
Rollenhagen A, Bischof H-J. Activity-dependent plasticity in visual forebrain areas of the zebra finch. Behavioural Brain Research.
Rollenhagen, Astrid +3 more
core +1 more source

