Results 31 to 40 of about 87,758 (253)
Mutant Tau knock-in mice display frontotemporal dementia relevant behaviour and histopathology [PDF]
, 2016 Peer ...
Drever, Benjamin D. +7 more
core +3 more sources
Basal forebrain circuit for sleep-wake control [PDF]
Nature Neuroscience, 2015 The mammalian basal forebrain (BF) has important roles in controlling sleep and wakefulness, but the underlying neural circuit remains poorly understood. We examined the BF circuit by recording and optogenetically perturbing the activity of four genetically defined cell types across sleep-wake cycles and by comprehensively mapping their synaptic ...
Min Xu +10 more
openaire +5 more sources
Advanced Healthcare Materials, EarlyView.ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee +10 more
wiley +1 more source
The endocranial morphology and inner ear of the abelisaurid theropod Aucasaurus garridoi [PDF]
, 2015 A partial cranial endocast and right inner ear of the Cretaceous abelisaurid dinosaur Aucasaurus garridoi were digitally reconstructed from CT scans.
Paulina Carabajal, Ariana +1 more
core +1 more source
Advanced Materials Technologies, EarlyView.This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang +4 more
wiley +1 more source
A direct cerebello-telencephalic projection in an electrosensory mormyrid fish [PDF]
, 1990 After injections of the posterior part of the lateral zone of the area dorsalis telencephali (Dlp) with either horseradish peroxidase or the newly available carbocyanine dye DiI, efferent cells were labeled in the valvula cerebelli of the mormyrid fish ...
Ebbesson +22 more
core +1 more source
An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids
Advanced Materials Technologies, EarlyView.This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto +6 more
wiley +1 more source
Anatomy and computational modeling of networks underlying cognitive-emotional interaction [PDF]
, 2013 The classical dichotomy between cognition and emotion equated the first with rationality or logic and the second with irrational behaviors. The idea that cognition and emotion are separable, antagonistic forces competing for dominance of mind has been ...
Basilis eZikopoulos +4 more
core +2 more sources
Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease
Advanced Science, EarlyView.ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan +17 more
wiley +1 more source
Central Executive Dysfunction and Deferred Prefrontal Processing in Veterans with Gulf War Illness. [PDF]
, 2013 Gulf War Illness is associated with toxic exposure to cholinergic disruptive chemicals. The cholinergic system has been shown to mediate the central executive of working memory (WM).
Bennett, Ilana J +7 more
core +2 more sources