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Neurological Disorders in Dogs: A Retrospective Analysis of Prevalence, Aetiology, Lesion Locations, and Regional Variations in Northeastern Iran [PDF]

Veterinary Medicine and Science
Background Neurological disorders in dogs are a significant concern in veterinary medicine and affect various breeds and ages. Previous studies have reported differing prevalence rates and aetiologies across regions, highlighting the need for a ...
Ali Behrouzian, Ali Asghar Sarchahi, Hadi Jabbari Noghabi   +2 more
doaj   +2 more sources

Cyclopia with proboscis: A rare congenital anomaly

Clinical Case Reports, 2021
Cyclopia with a proboscis, a rare congenital anomaly, and a severe form of holoprosencephaly occur as a result of incomplete separation of prosencephalon into two halves of hemispheres during organogenesis.
Asma Kunwar, Bibek Man Shrestha, Suraj Shrestha, Pooja Paudyal, Suniti Rawal   +4 more
doaj   +2 more sources

EARLY-ONSET CENTRAL DIABETES INSIPIDUS IN A NEWBORN WITH HOLOPROSENCEPHALY

İstanbul Tıp Fakültesi Dergisi, 2021
Holoprosencephaly is a complex brain malformation caused by the inability of the prosencephalon to divide to form the cerebral hemispheres. Central diabetes insipidus (CDI), as a result of a defect in vasopressin release, may be seen due to the abnormal ...
Mustafa Törehan Aslan, Elmas Zeynep İnce, Emine Asuman Çoban   +2 more
doaj   +3 more sources

Semilobar holoprosencephaly associated with maternal diabetes in a toddler: A case report [PDF]

Radiology Case Reports
Holoprosencephaly is a rare congenital malformation of the forebrain caused by incomplete division of the prosencephalon during early embryonic development, and semilobar holoprosencephaly represents the intermediate form of the spectrum.
Cihan Çelik, Fahad Mirre, İsmail Gedi İbrahim   +2 more
doaj   +2 more sources

A case of early diagnosis of alobar holoprosencephaly from Pakistan: importance of prompt prenatal imaging [PDF]

Journal of Medical Case Reports
Background Holoprosencephaly (HPE) is a rare congenital condition encompassing incomplete midline cleavage of the prosencephalon and associated craniofacial abnormalities.
Romesa Qazi, Ayesha Liaquat, Qurat Ul Ain Qazi, Bushra Tariq, Shajie Ur Rehman Usmani   +4 more
doaj   +2 more sources

Maternal diabetes disrupts early corticogenesis through altered mitotic gene regulation: a transcriptomic analysis [PDF]

Frontiers in Endocrinology
Maternal diabetes is linked to neurodevelopmental impairments in offspring, but the underlying molecular mechanisms remain unclear. Early cortical neurogenesis is a critical window vulnerable to maternal metabolic disturbances.
Rocío Valle-Bautista, Diana S. de la Merced-García, Dafne A. Díaz-Piña, Néstor Fabián Díaz, Daniela Ávila-González, Anayansi Molina-Hernández   +5 more
doaj   +2 more sources

Case Report: Hypodipsic hypernatremia secondary to hydrocephalus in a dog [PDF]

Frontiers in Veterinary Science
A 6-year-old male castrated golden retriever was presented for inappetence, lethargy, and progressive obtundation. A chemistry panel showed hypernatremia (>190 mmol/L) and hyperchloremia (157 mmol/L).
Maddisen W. Antes, Amelia C. Corona, Helena Rylander   +2 more
doaj   +2 more sources

Multi-neuromeric origin of tyrosine hydroxylase-positive neurons within the substantia nigra and ventral tegmental area [PDF]

Frontiers in Neuroanatomy
During early developmental stages, the brain is divided into three primary regions: the forebrain (prosencephalon), the hindbrain (rhombencephalon), and the spinal cord.
José L. Ferran, José L. Ferran, Franco Lucero-Arteaga, Franco Lucero-Arteaga, Abdelmalik Ayad, Abdelmalik Ayad, Yevheniy Kutsenko, Yevheniy Kutsenko, A. Alonso, A. Alonso, B. Ribeiro Do-Couto, B. Ribeiro Do-Couto, M. Á. García-Cabezas, Kuei Y. Tseng   +13 more
doaj   +2 more sources

Holoprosencephaly: Review of Embryology, Clinical Phenotypes, Etiology and Management

Children, 2023
Holoprosencephaly (HPE) is the most common malformation of the prosencephalon in humans. It is characterized by a continuum of structural brain anomalies resulting from the failure of midline cleavage of the prosencephalon.
Maísa Malta, Rowim AlMutiri, Christine Saint Martin, Myriam Srour   +3 more
doaj   +1 more source

Semilobarholoprosencephaly – A Dreading Congenital Anomaly [PDF]

Journal of Clinical and Diagnostic Research, 2017
Holoprosencephaly (HPE) is a group of structural abnormalities of brain that is an important cause of childhood mortality and morbidity. They usually occur due to impaired midline cleavage of embryonic forebrain i.e., failure of differentiation of the ...
Bhushita B Lakhkar, Bhushan N Lakhkar, Bhavana B Lakhkar   +2 more
doaj   +1 more source