Results 1 to 10 of about 11,012 (235)

Ethanol itself is a holoprosencephaly-inducing teratogen. [PDF]

PLoS ONE, 2017
Ethanol is a teratogen, inducing a variety of structural defects in developing humans and animals that are exposed in utero. Mechanisms of ethanol teratogenicity in specific defects are not well understood.
Mingi Hong, Robert S Krauss
doaj   +3 more sources

HOLOPROSENCEPHALY [PDF]

American Journal of Obstetrics and Gynecology, 2020
Holoprosencephaly is a developmental disorder that results when the forebrain of the embryo fails to divide and form the right and left halves of the brain.
P. Kruszka, A. Gropman, Maximilian Muenke   +2 more
semanticscholar   +6 more sources

Holoprosencephaly

Orphanet Journal of Rare Diseases, 2007
Holoprosencephaly (HPE) is a complex brain malformation resulting from incomplete cleavage of the prosencephalon, occurring between the 18th and the 28th day of gestation and affecting both the forebrain and the face. It is estimated to occur in 1/16,000
Henry Catherine, Pasquier Laurent, Bendavid Claude, Dubourg Christèle, Odent Sylvie, David Véronique   +5 more
doaj   +5 more sources

Cyclopia: Facial deformity indicating severe holoprosencephaly with imaging findings of brain: A case report [PDF]

Radiology Case Reports
Holoprosencephaly results from incomplete separation of the cerebral hemispheres. Cyclopia is a facial manifestation of Holoprosencephaly, characterized by a midline single orbit and proboscis.
Shiva Aryal, MBBS, Bhumika Rimal, MBBS, Sharma Paudel, MD, Kundan Marasini, MD   +3 more
doaj   +2 more sources

Semilobar holoprosencephaly associated with maternal diabetes in a toddler: A case report [PDF]

Radiology Case Reports
Holoprosencephaly is a rare congenital malformation of the forebrain caused by incomplete division of the prosencephalon during early embryonic development, and semilobar holoprosencephaly represents the intermediate form of the spectrum.
Cihan Çelik, Fahad Mirre, İsmail Gedi İbrahim   +2 more
doaj   +2 more sources

Congenital external hydrocephalus: A rare presentation of lobar holoprosencephaly in a neonate [PDF]

Radiology Case Reports
External hydrocephalus is a rare condition characterized by abnormal cerebrospinal fluid (CSF) accumulation in the subarachnoid space, often associated with developmental anomalies.
Rakshanda Agrawal, MBBS, Nishant Raj, MD, Vaishali Dhawan, MD, Pratapsingh Parihar, MD, Nikita Bora, MBBS   +4 more
doaj   +2 more sources

Holoprosencephaly [PDF]

Autopsy and Case Reports, 2017
Ameer Hamza, Martha Jaye Higgins
doaj   +3 more sources

The assessment of holoprosencephaly cases in the last 10 years [PDF]

Ķazaķstannyṇ Klinikalyķ Medicinasy, 2021
Holoprosencephaly is a disorder of cleavage failure or incomplete differentiation of the forebrain structures. Chromosomal anomalies and environmental teratogenic factors play a role in its development. We reported 22 cases of holoprosencephaly diagnosed
Hulusi Goktug Gurer, Ozlem Ozgur Gursoy, Ceren Yildiz Eren   +2 more
doaj   +1 more source

Semilobar Holoprosencephaly with Cebocephaly: A Case Report

Journal of College of Medical Sciences-Nepal, 2021
Holoprosencephaly is a rare congenital malformation affecting 6 to 12:10,000 live-born infants and is characterized by failure of separation of cerebral hemispheres.
Jeevan Jyothish, Rituparna Das
doaj   +1 more source

Holoprosencephaly: Review of Embryology, Clinical Phenotypes, Etiology and Management

Children, 2023
Holoprosencephaly (HPE) is the most common malformation of the prosencephalon in humans. It is characterized by a continuum of structural brain anomalies resulting from the failure of midline cleavage of the prosencephalon.
Maísa Malta, Rowim AlMutiri, C. Martin, M. Srour   +3 more
semanticscholar   +1 more source