Results 11 to 20 of about 11,012 (235)
Donald School Journal of Ultrasound in Obstetrics and Gynecology, 2020 Holoprosencephaly is a birth defect that leads to an abnormal brain development where the brain fails to divide into two hemispheres. Possible causes are environmental or genetic factors. Holoprosencephaly can include craniofacial abnormalities in most of the cases.
Al-Khawaja, Fatima +4 more
openaire +4 more sources
EARLY-ONSET CENTRAL DIABETES INSIPIDUS IN A NEWBORN WITH HOLOPROSENCEPHALY
İstanbul Tıp Fakültesi Dergisi, 2021 Holoprosencephaly is a complex brain malformation caused by the inability of the prosencephalon to divide to form the cerebral hemispheres. Central diabetes insipidus (CDI), as a result of a defect in vasopressin release, may be seen due to the abnormal ...
Mustafa Törehan Aslan +2 more
doaj +3 more sources
Cohesin complex-associated holoprosencephaly. [PDF]
Brain : a journal of neurology, 2019 Marked by incomplete division of the embryonic forebrain, holoprosencephaly is one of the most common human developmental disorders. Despite decades of phenotype-driven research, 80-90% of aneuploidy-negative holoprosencephaly individuals with a probable
P. Kruszka +34 more
semanticscholar +5 more sources
Identifying environmental risk factors and gene-environment interactions in holoprosencephaly
Birth Defects Research, 2020 Holoprosencephaly is the most common malformation of the forebrain (1 in 250 embryos) with severe consequences for fetal and child development. This study evaluates nongenetic factors associated with holoprosencephaly risk, severity, and gene–environment
Y. Addissie +8 more
semanticscholar +2 more sources
Antenatally diagnosed alobar holoprosencephaly: A report of two cases
CHRISMED Journal of Health and Research, 2017 Holoprosencephaly is a complex developmental abnormality of the brain arising from the failure of cleavage of the prosencephalon. The condition termed “holoprosencephaly” includes cyclopia, cebocephaly, ethmocephaly, and median cleft.
C R Srinivasa Babu +3 more
doaj +2 more sources
Prenatal Diagnosis of Alobar Holoprosencephaly with Cystic Hygroma [PDF]
Taiwanese Journal of Obstetrics & Gynecology, 2006 Objective: Holoprosencephaly is a kind of brain anomaly characterized by inadequate cleavage of the prosencephalon during early embryogenesis. In addition, holoprosencephaly associated with cystic hygroma and hydrops fetalis has never been reported.
Tsung-Ying Hsieh +3 more
doaj +2 more sources
Boc modifies the spectrum of holoprosencephaly in the absence of Gas1 function
Biology Open, 2014 Holoprosencephaly is a heterogeneous developmental malformation of the central nervous system characterized by impaired forebrain cleavage, midline facial anomalies and wide phenotypic variation.
Maisa Seppala +3 more
doaj +6 more sources
A case of holoprosencephaly and a little review
Human Pathology: Case Reports, 2019 Holoprosencephaly (HPE) is a birth defect that occurs during the first weeks of pregnancy and as a result the prosencephalon does not clearly divide in diencephalon, two halves of the telencephalon and lateral ventricles in the brain of the fetus and, in
Agustín Castañeyra-Perdomo +6 more
doaj +2 more sources
White Matter Maturation in Holoprosencephaly
Pediatric Neurology Briefs, 2003 White matter maturation in holoprosencephaly (HPE) was assessed by MRI scans in 47 patients (age 1 day to 16 years, median age 7 months) evaluated at the University of California, San Francisco.
J Gordon Millichap
doaj +2 more sources
Iniencephaly and Holoprosencephaly: Report of a Rare Association [PDF]
Case Reports in Obstetrics and Gynecology, 2014 The aim of this study is to discuss a rare association of iniencephaly and holoprosencephaly and to state the importance of pregnancy termination in early gestational weeks.
Aytekin Tokmak +3 more
doaj +2 more sources