Results 21 to 30 of about 526,321 (280)

Cell Assemblies of the Basal Forebrain [PDF]

The Journal of Neuroscience, 2015
The basal forebrain comprises several heterogeneous neuronal subgroupings having modular projection patterns to discrete sets of cortical subregions. Each cortical region forms recurrent projections, via prefrontal cortex, that reach the specific basal forebrain subgroups from which they receive afferents.
David Tingley, Andrew S. Alexander, Laleh K. Quinn, Andrea A. Chiba, Douglas A. Nitz   +4 more
openaire   +2 more sources

Redundant basal forebrain modulation in taste aversion memory formation

, 2013
Mnemonic deficits resulting from excitotoxic lesion of the basal forebrain have been classically attributed to the resulting depletion of cortical acetylcholine activity.
Ranier Gutiérrez (17254819), Christopher E. Ormsby (7444739), Ricardo Silva-Gandarias (17254822), Luis Ramírez-Trejo (17254816), Federico Bermúdez-Rattoni (17254810), Humberto Gutierrez (17159095), Maria Isabel Miranda (17254813)   +6 more
core   +5 more sources

Activation of brain‐derived neurotrophic factor signaling in the basal forebrain reverses acute sleep deprivation‐induced fear memory impairments

Brain and Behavior, 2020
Introduction The mechanisms underlying sleep deprivation‐induced memory impairments and relevant compensatory signaling pathways remain elusive. We tested the hypothesis that increased brain‐derived neurotrophic factor (BDNF) expression in the basal ...
Tao Ma, Hao Zhang, Zhi‐Peng Xu, Yan Lu, Qiang Fu, Wei Wang, Guan‐Hua Li, Ying‐Ying Wang, Yi‐Tian Yang, Wei‐Dong Mi   +9 more
doaj   +1 more source

Sleep-wake sensitive mechanisms of adenosine release in the basal forebrain of rodents : an in vitro study [PDF]

, 2013
Adenosine acting in the basal forebrain is a key mediator of sleep homeostasis. Extracellular adenosine concentrations increase during wakefulness, especially during prolonged wakefulness and lead to increased sleep pressure and subsequent rebound sleep.
Sims, Robert E., Houdini Ho Tin Wu, Tin Wu, Sims Robert Edward, Dale, Nicholas, Sims, Robert, Wu, Houdini Ho Tin, Houdini Ho, Dale Nicholas, Robert Edward Sims, Nicholas Dale, Wu Houdini Ho Tin   +11 more
core   +2 more sources

An Evolutionary Interpretation of Teleostean Forebrain Anatomy [PDF]

, 2009
During the past few years, our investigations of the forebrain in the zebrafish (a teleost fish) have shown that its molecular anatomy and expression patterns of genes involved in the regulation of neuronal transmitter phenotypes, such as gamma ...
Wullimann, M., Mueller, T., Wullimann, Mario F., Mueller, Thomas   +3 more
core   +1 more source

Physiological properties of cholinergic and non-cholinergic magnocellular neurons in acute slices from adult mouse nucleus basalis. [PDF]

PLoS ONE, 2010
BackgroundThe basal forebrain is a series of nuclei that provides cholinergic input to much of the forebrain. The most posterior of these nuclei, nucleus basalis, provides cholinergic drive to neocortex and is involved in arousal and attention.
Tristan Hedrick, Jack Waters
doaj   +1 more source

Cholinergic Basal Forebrain Volumes Predict Gait Decline in Parkinson's Disease. [PDF]

, 2020
BACKGROUND: Gait disturbance is an early, disabling feature of Parkinson's disease (PD) that is typically refractory to dopaminergic medication. The cortical cholinergic system, originating in the nucleus basalis of Meynert of the basal forebrain, has ...
Galna, Brook, Wilson, Joanna, Sue Lord, Alcock, Lisa, Galna, B., Duncan, GW, Yarnall, Alison, Rochester, Lynn, Lord, S., Taylor, J.‐P., Lord, S, Khoo, TK, Duncan, Gordon W., Rachael A. Lawson, Lawson, RA, Burn, DJ, Morris, R., Nicola J. Ray, O'Brien, John T, Joanna Wilson, Craig, Chesney E., Lord, Sue, Ray, Nicola J., Alcock, L., Gordon W. Duncan, Yarnall, A.J., Taylor, JP, Khoo, T.K., Craig, C.E., Morris, Rosie, John‐Paul Taylor, Alcock, L, Alison J. Yarnall, Rochester, L., Duncan, G.W., Ray, NJ, Lawson, R.A., Chesney E. Craig, John T. O'Brien, Ray, Nicola, Yarnall, AJ, Brook Galna, Khoo, Tien K., Ray, N.J., Taylor, John-Paul, Rosie Morris, Tien K. Khoo, Wilson, J., Burn, D.J., Duncan, Gordon W, Lisa Alcock, Taylor, John‐Paul, Lynn Rochester, Burn, David J, Lawson, Rachael A., O'Brien, J.T., Burn, David J., David J. Burn, O'Brien, JT, Morris, R, Wilson, J, Yarnall, Alison J., O'Brien, John T., Rochester, L, Lawson, Rachael, Khoo, Tien K, Craig, Chesney, Craig, CE, Galna, B   +68 more
core   +2 more sources

In vivo function of NGF/TrkA signaling in the cholinergic neurons of the murine basal forebrain [PDF]

, 2005
The neurotrophins are a family of secreted proteins that potently regulate diverse neuronal responses. The neurotrophin nerve growth factor (NGF) and its receptors TrkA and p75 are well characterized to control survival, differentiation and function of ...
Mueller, Markus
core   +1 more source

Cholinergic cells in the nucleus basalis of mice express the N-methyl-D-aspartate-receptor subunit NR2C and its replacement by the NR2B subunit enhances frontal and amygdaloid acetylcholine levels [PDF]

, 2006
It is known that glutamatergic and cholinergic systems interact functionally at the level of the cholinergic basal forebrain. The N-methyl-D-aspartate receptor (NMDA-R) is a multiprotein complex composed of NR1, NR2 and/or NR3 subunits.
Dolga, A.,, Eisel, U.L.M.,, Dolga, Amalia, Dere, E., I. Pieri, L. Marchetti, Dere, E.,, Pieri, I., Marchetti, L., De Souza Silva, M. A., Huston, J. P., Marchetti, L.,, A. Dolga, J. P. Huston, Dolga, Amalia; id_orcid, U. L. M. Eisel, Huston, J.P.,, Pieri, I.,, Eisel, U. L. M., Souza Silva, M.A. De,, E. Dere, M. A. De Souza Silva, Eisel, U. L. M.; id_orcid   +22 more
core   +1 more source

Chemical genetic activation of the cholinergic basal forebrain hippocampal circuit rescues memory loss in Alzheimer’s disease

Alzheimer’s Research & Therapy, 2022
Background The degeneration of the cholinergic circuit from the basal forebrain to the hippocampus contributes to memory loss in patients suffering from Alzheimer’s disease (AD).
Weilin Liu, Jianhong Li, Minguang Yang, Xiaohua Ke, Yaling Dai, Huawei Lin, Sinuo Wang, Lidian Chen, Jing Tao   +8 more
doaj   +1 more source