Results 11 to 20 of about 131,181 (262)
Butyrylcholinesterase and the cholinergic system
Neuroscience, 2013 The cholinergic system plays important roles in neurotransmission in both the peripheral and central nervous systems. The cholinergic neurotransmitter acetylcholine is synthesized by choline acetyltransferase (ChAT) and its action terminated by acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE).
Reid, G.A., Chilukuri, N., Darvesh, S.
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Advances in the study of cholinergic circuits in the central nervous system
Annals of Clinical and Translational Neurology, 2023 Objective Further understanding of the function and regulatory mechanism of cholinergic neural circuits and related neurodegenerative diseases. Methods This review summarized the research progress of the central cholinergic nervous system, especially for
Ganghua He +3 more
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Multiple Sources of Cholinergic Input to the Superior Olivary Complex
Frontiers in Neural Circuits, 2021 The superior olivary complex (SOC) is a major computation center in the brainstem auditory system. Despite previous reports of high expression levels of cholinergic receptors in the SOC, few studies have addressed the functional role of acetylcholine in ...
Nichole L. Beebe +5 more
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Orthopedic Reviews, 2009 Anti-cholinergic agents are used in the treatment of several pathological conditions. Therapy regimens aimed at up-regulating cholinergic functions, such as treatment with acetylcholinesterase inhibitors, are also currently prescribed.
Sture Forsgren +6 more
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Cholinergic Mechanisms in Spinal Locomotion - Potential Target for Rehabilitation Approaches
Frontiers in Neural Circuits, 2014 Previous experiments implicate cholinergic brainstem and spinal systems in the control of locomotion. Our results demonstrate that the endogenous cholinergic propriospinal system, acting via M2 and M3 muscarinic receptors, is capable of consistently ...
L M Jordan +9 more
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Cholinergic signaling exerts protective effects in models of sympathetic hyperactivity-induced cardiac dysfunction. [PDF]
PLoS ONE, 2014 Cholinergic control of the heart is exerted by two distinct branches; the autonomic component represented by the parasympathetic nervous system, and the recently described non-neuronal cardiomyocyte cholinergic machinery. Previous evidence has shown that
Mariana Gavioli +14 more
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Cholinergic Signaling, Neural Excitability, and Epilepsy
Molecules, 2021 Epilepsy is a common brain disorder characterized by recurrent epileptic seizures with neuronal hyperexcitability. Apart from the classical imbalance between excitatory glutamatergic transmission and inhibitory γ-aminobutyric acidergic transmission ...
Yu Wang, Bei Tan, Yi Wang, Zhong Chen
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Characterization of Channelrhodopsin and Archaerhodopsin in Cholinergic Neurons of Cre-Lox Transgenic Mice. [PDF]
PLoS ONE, 2016 The study of cholinergic signaling in the mammalian CNS has been greatly facilitated by the advent of mouse lines that permit the expression of reporter proteins, such as opsins, in cholinergic neurons. However, the expression of opsins could potentially
Tristan Hedrick +7 more
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Dissociable roles for the striatal cholinergic system in different flexibility contexts
IBRO Neuroscience Reports, 2022 The production of behavioural flexibility requires the coordination and integration of information from across the brain, by the dorsal striatum. In particular, the striatal cholinergic system is thought to be important for the modulation of striatal ...
Brendan Williams, Anastasia Christakou
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Cholinergic connectivity: it’s implications for psychiatric disorders.
Frontiers in Cellular Neuroscience, 2013 Acetylcholine has been implicated in both the pathophysiology and treatment of a number of psychiatric disorders, with most of the data related to its role and therapeutic potential focussing on schizophrenia.
Elizabeth eScarr +9 more
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