Results 331 to 340 of about 2,497,858 (389)

Muscarinic cholinergic receptors in goldfish retina

Life Sciences, 1979
Abstract Using 3 H-Quinuclinidyl Benzilate ( 3 H-QNB) as a high affinity ligand for quantitative studies of specific binding to muscarinic cholinergic receptors we have demonstrated the presence of such receptors in homogenates of goldfish retina. Only one set of binding sites could be detected with an apparent dissociation constant of 1.9 × 10 −10
J A, Moreno-Yanes, H R, Mahler
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Cholinergic muscarinic receptors in rat cochlea

Brain Research, 1988
Specific 3H-1-quinuclidinylbenzilate (3H-1-QNB) binding to rat cochlea homogenates occurs to a homogeneous class of binding sites with Kd = 0.13 +/- 0.01 nM and Bmax = 0.57 +/- 0.07 fmol per cochlea. Binding is stereoselectively inhibited by benzetimide enantiomers.
Y J, van Megen, A B, Klaassen, J F, Rodrigues de Miranda, W, Kuijpers   +3 more
openaire   +2 more sources

Affinity Chromatography of Cholinergic Receptor Proteins

Journal of Receptor Research, 1984
Cholinergic binding proteins were purified from torpedo electric organ. The preparation comprises: solubilization by non-ionic detergents followed by unspecific prepurification. For prepurification the double reversed technique proved to be very useful. Finally we applied affinity chromatography.
W H, Hopff, D M, Bodmer, P G, Waser
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Nicotinic cholinergic receptors in brain synaptosomes

Brain Research, 1979
In order to elucidate pharmacological characteristics of nicotinic receptors in the brain, competitive binding of nicotine analogues or cholinergic agents to brain particles was studied utilizing [3H]nicotine. The binding of [3H]nicotine to brain crude nitochondrial or synaptosomal fraction was progressively inhibited by the addition of increasing ...
K, Yoshida, H, Imura
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Hippocampal sympathetic ingrowth and cholinergic denervation alter hippocampal muscarinic cholinergic receptors

Hippocampus, 1994
AbstractCholinergic denervation of the hippocampus by medial septal (MS) lesions results in the ingrowth of peripheral sympathetic fibers, originating from the superior cervical ganglia, into the hippocampus. To determine the effect of hippocampal sympathetic ingrowth (HSI) [3H]‐QNB (L‐quinuclidinyl [benzilic‐4, 4(n)] benzilate) binding was assessed in
L E, Harrell, V, Ayyagari, A, Peagler, D S, Parsons   +3 more
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[Cholinergic receptors and anesthesia].

Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1992
Postsynaptic chemically controlled ion channels are a possible location for the action of anaesthetics. The nicotinic acetylcholine receptor (AcChoR) is a member of a superfamily of chemically controlled ion channels, which have a large number of structural similarities in common.
P H, Tonner, K W, Miller
openaire   +1 more source

CHOLINERGIC RECEPTOR DESENSITIZATION*

Annals of the New York Academy of Sciences, 1976
W L, Nastuk, C H, Wolfson
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Cholinergic receptors as target for cancer therapy in a systems medicine perspective.

Current molecular medicine, 2014
P. Russo, A. D. Bufalo, M. Milić, Gianluca Salinaro, M. Fini, A. Cesario   +5 more
semanticscholar   +1 more source

Pharmacological Characterization of GSK573719 (Umeclidinium): A Novel, Long-Acting, Inhaled Antagonist of the Muscarinic Cholinergic Receptors for Treatment of Pulmonary Diseases

Journal of Pharmacology and Experimental Therapeutics, 2013
M. Salmon, M. Luttmann, J. Foley, Peter T. Buckley, D. Schmidt, M. Burman, E. Webb, C. Dehaas, C. J. Kotzer, V. Barrett, R. Slack, H. Sarau, Michael R. Palovich, Dramane I. Lainé, D. Hay, W. Rumsey   +15 more
semanticscholar   +1 more source

Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system.

Annual Review of Pharmacology and Toxicology, 2007
J. Dani, D. Bertrand
semanticscholar   +1 more source