Results 211 to 220 of about 90,058 (326)

Type‐Specific Single‐Neuron Analysis Reveals Mitochondrial DNA Maintenance Failure Affecting Atrophying Pontine Neurons Differentially in Lewy Body Dementia Syndromes

open access: yesAging Cell, Volume 24, Issue 8, August 2025.
(a) Mitochondria contain wild‐type (black)/mutant (red) mtDNA; exceeding the mtDNA mutation threshold compromises OXPHOS, potentially driving degeneration of neurons vulnerable to age‐related neurodegenerative disease. Cellular compensations that is, mtDNA copy number upregulation and crosstalk with nuclear DNA may fail, driving neurodegeneration ...
Eloise J. Stephenson   +10 more
wiley   +1 more source

Microglia in Post‐Traumatic Brain Injury (TBI) Cognitive Impairment: From Pathological Changes to Therapeutic Approaches

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 8, August 2025.
This review systematically analyzes the multi‐stage dynamic pathological evolution of microglia and therapy strategies targeting microglia in PSCI, providing a new perspective for a deeper understanding of the microscopic mechanisms of the disease. ABSTRACT Background Traumatic brain injury (TBI), as a common and serious neurological disease, brings ...
Ningcen Li   +12 more
wiley   +1 more source

The Application of Polymeric Nanoparticles as Drug Delivery Carriers to Cells in Neurodegenerative Diseases

open access: yesCell Proliferation, Volume 58, Issue 8, August 2025.
Polymeric nanoparticles represent promising drug (gene) delivery carriers to the brain due to their unique advantages to facilitate the penetration of blood–brain barrier and endocytosis of neuronal cells in neurodegenerative diseases. ABSTRACT In spite of great advances in modern medicine, there are a few effective strategies for the treatment of ...
Lian Jin   +4 more
wiley   +1 more source

Effect of Intracavernous Simultaneous Injection of Acetylcholine and VIP on Canine Penile Erection [PDF]

open access: yes, 1992
Aboseif, Sherif R.   +5 more
core  

Serum Cholinesterase

open access: yesClinical Chemistry, 1969
R V, LaMotta, R B, McComb, H J, Wetstone
openaire   +2 more sources

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