Results 221 to 230 of about 90,058 (326)

A Review of Chronic Wounds and Their Impact on Negative Affect, Cognition, and Quality of Life

open access: yesInternational Wound Journal, Volume 22, Issue 8, August 2025.
ABSTRACT Chronic wounds represent a substantial socioeconomic, financial, and psychological burden. We examine preclinical and clinical evidence assessing the impact of chronic wounds on negative affect, cognition, and quality of life and discuss potential mechanisms underlying the link between chronic wounds and negative affect and cognition. There is
Maria C. Redmond   +2 more
wiley   +1 more source

The Tacrine‐Induced Endoplasmic Reticulum Stress in AChE‐Expressed Cells Leads to Improper Assembly and Transport of the Oligomeric Enzyme: Reversal by Trehalose

open access: yesJournal of Neurochemistry, Volume 169, Issue 8, August 2025.
Acetylcholinesterase (AChE) inhibitors are a class of drugs to treat Alzheimer's disease (AD). Our study reveals that some AChE inhibitors, for example, tacrine, disrupt the proper assembly and transport of oligomeric forms of AChE, resulting in endoplasmic reticulum (ER) stress. The ER stress ultimately leads to cell apoptosis. This tacrine‐induced ER
Xiaoyang Wang   +8 more
wiley   +1 more source

Association of Butyryl Cholinesterase and Recurrent Ischemic Stroke: A Cross-Sectional Study. [PDF]

open access: yesInt J Gen Med
Chen R   +12 more
europepmc   +1 more source

Enteric neuropathy and the vagus nerve: Therapeutic implications

open access: yesNeurogastroenterology &Motility, Volume 37, Issue 8, August 2025.
Abstract Enteric neuropathies are characterized by abnormalities of gut innervation, which includes the enteric nervous system, inducing severe gut dysmotility among other dysfunctions. Most of the gastrointestinal tract is innervated by the vagus nerve, the efferent branches of which have close interconnections with the enteric nervous system and ...
Bruno Bonaz
wiley   +1 more source

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