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Cholinesterase inhibitors and memory
Chemico-Biological Interactions, 2010A consensus exists that cholinesterase inhibitors (ChEIs) are efficacious for mild to moderate Alzheimer's Disease (AD). Unfortunately, the number of non-responders is large and the therapeutic effect is usually short-lasting. In experimental animals, ChEIs exert three main actions: inhibit cholinesterase (ChE), increase extracellular levels of brain ...
PEPEU, GIANCARLO +1 more
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Cholinesterases and Cholinesterase Inhibitors
Current Enzyme Inhibition, 2008Sarka Stepankova, Karel Komers
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Benzamides and cholinesterases.
Research communications in chemical pathology and pharmacology, 1987At certain doses metoclopramide (MT), sulpiride and bromopride produce anti-cholinesterase effects as shown by studies on the serum and erythrocyte cholinesterases of the rabbit and the dog, and by those on the hypotensive effect of ACh incubated with rabbit serum in the presence or absence of MT. The anti-cholinesterase effect of MT was more intensive
VACCA C +3 more
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Science, 1945 Ontogenesis of Cholinesterases
1963Cholinesterases (ChE’s) and particularly acetylcholinesterase (AChE) were early (Loewi and Navratil 1926) associated with rapidly occurring events of neurohumoral or synaptic transmission and with function and motility (BACQ 1935 a). Thus, together with enzymes concerned with adrenergic function, ChE’s are dramatically different from enzymes concerned ...
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