Results 11 to 20 of about 1,946 (125)

Sulfate de dermatane et sulfate d'heparitine du foie de boeuf

open access: yes, 1972
Beef liver dermatan sulfate can be separated into two distinct fractions by electrophoresis on cellulose acetate. The faster moving Fraction II contains more sulfate. Both fractions are digested by chondroitinase ABC.
Ameryckx, Jean Pierre   +2 more
core   +2 more sources

Increased Cerebral Serum Amyloid A2 and Parameters of Oxidation in Arylsulfatase B (N-Acetylgalactosamine-4-Sulfatase)-Null Mice

open access: yesJournal of Alzheimer's disease reports, 2023
Background: Chondroitin sulfate and chondroitin sulfate proteoglycans have been associated with Alzheimer’s disease (AD), and the impact of modified chondroitin sulfates is being investigated in several animal and cell-based models of AD.
S. Bhattacharyya, J. Tobacman
semanticscholar   +2 more sources

Enzymatic methods for the determination of small quantities of isomeric chondroitin sulfates.

open access: yesJournal of Biological Chemistry, 1968
Micromethods have been developed for the measurement of as little as 3 µg of chondroitin sulfate A, B, or C in mixtures with other mucopolysaccharides by the use of chondroitinase-ABC, chondroitinase-AC, chondro-4-sulfatase, and chondro-6-sulfatase. With
H. Saito, T. Yamagata, S. Suzuki
semanticscholar   +1 more source

Purification and properties of bacterial chondroitinases and chondrosulfatases.

open access: yesJournal of Biological Chemistry, 1968
1. An enzyme, "chondroitinase-ABC," has been purified to apparent homogeneity from extracts of Proteus vulgaris, NCTC 4636, which was adapted on a medium containing chondroitin sulfate C. It has the following properties.
T. Yamagata   +3 more
semanticscholar   +1 more source

Formation of three types of disulfated disaccharides from chondroitin sulfates by chondroitinase digestion.

open access: yesJournal of Biological Chemistry, 1968
By means of enzymatic digestion with chondroitinase-ABC, a novel unsaturated disaccharide bearing two sulfate residues has been derived from chondroitin sulfate of squid cartilage.
S. Suzuki   +6 more
semanticscholar   +1 more source

Exogenous recombinant N-acetylgalactosamine-4-sulfatase (Arylsulfatase B; ARSB) inhibits progression of B16F10 cutaneous melanomas and modulates cell signaling

open access: yesbioRxiv, 2023
In the syngeneic, subcutaneous B16F10 mouse model of malignant melanoma, treatment with exogenous ARSB markedly reduced tumor size and extended survival.
S. Bhattacharyya   +4 more
semanticscholar   +1 more source

Proteoglycan carrier of human platelet factor 4. Isolation and characterization.

open access: yesJournal of Biological Chemistry, 1982
A large scale purification procedure for the human platelet factor 4 proteoglycan carrier molecule has been developed. A yield of 46% and a 33,000-fold purification have been achieved, using poly-L-lysine-Sepharose affinity column chromatography, PF4 ...
S. S. Huang, J. Huang, T. Deuel
semanticscholar   +1 more source

Synthesis of chondroitin sulfate D and heparin proteoglycans in murine lymph node-derived mast cells. The dependence on fibroblasts.

open access: yesJournal of Biological Chemistry, 1990
Proteoglycans synthesized in cultured mast cells derived from horse serum-immunized lymph node cells were analyzed. Treatment of the 35S-proteoglycans extracted from these cells with either chondroitinase ABC or AC resulted in 95% +/- 7% and 84% +/- 7 ...
S. Davidson   +4 more
semanticscholar   +1 more source

Profound Impact of Decline in N-Acetylgalactosamine-4-Sulfatase (Arylsulfatase B) on Molecular Pathophysiology and Human Diseases

open access: yesInternational Journal of Molecular Sciences, 2022
The enzyme N-acetylgalactosamine-4-sulfatase (Arylsulfatase B; ARSB) was originally identified as a lysosomal enzyme which was deficient in Mucopolysaccharidosis VI (MPS VI; Maroteaux-Lamy Syndrome).
J. Tobacman, S. Bhattacharyya
semanticscholar   +1 more source

Riding the sulfur cycle - metabolism of sulfonates and sulfate esters in Gram-negative bacteria [PDF]

open access: yes, 2017
Sulfonates and sulfate esters are widespread in nature, and make up over 95% of the sulfur content of most aerobic soils. Many microorganisms can use sulfonates and sulfate esters as a source of sulfur for growth, even when they are unable to metabolize ...
Kertesz, Michael A.
core  

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