Results 301 to 310 of about 118,065 (344)
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ACS Nano, 2023
As chondrocytes from osteoarthritic cartilage usually exhibit aging and senescent characteristics, targeting aging chondrocytes could be a potential therapeutic strategy. In this study, exosomes derived from umbilical cord-derived mesenchymal stem cells (
Hongfu Cao +9 more
semanticscholar +1 more source
As chondrocytes from osteoarthritic cartilage usually exhibit aging and senescent characteristics, targeting aging chondrocytes could be a potential therapeutic strategy. In this study, exosomes derived from umbilical cord-derived mesenchymal stem cells (
Hongfu Cao +9 more
semanticscholar +1 more source
Annals of the Rheumatic Diseases, 2022
Objectives To investigate the role of mechanical stress in cartilage ageing and identify the mechanistic association during osteoarthritis (OA) progression.
Haiyan Zhang +13 more
semanticscholar +1 more source
Objectives To investigate the role of mechanical stress in cartilage ageing and identify the mechanistic association during osteoarthritis (OA) progression.
Haiyan Zhang +13 more
semanticscholar +1 more source
ACS Applied Materials and Interfaces, 2020
Targeted delivery to the diseased cell or tissue is the key to the successful clinical use of nucleic acid drugs. In particular, delivery of microRNA-140 (miRNA-140, miR-140) into chondrocytes across the dense, nonvascular extracellular matrix of ...
Yujie Liang +7 more
semanticscholar +1 more source
Targeted delivery to the diseased cell or tissue is the key to the successful clinical use of nucleic acid drugs. In particular, delivery of microRNA-140 (miRNA-140, miR-140) into chondrocytes across the dense, nonvascular extracellular matrix of ...
Yujie Liang +7 more
semanticscholar +1 more source
The International Journal of Biochemistry & Cell Biology, 2003
The chondrocyte is the resident cell of cartilage that is a prominent tissue in the embryo acting as a template for the development of skeletal elements. In the adult, the distribution of permanent cartilage is much more restricted and is necessary for mechanical support, growth and movement.
Archer, C W, Francis-West, P
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The chondrocyte is the resident cell of cartilage that is a prominent tissue in the embryo acting as a template for the development of skeletal elements. In the adult, the distribution of permanent cartilage is much more restricted and is necessary for mechanical support, growth and movement.
Archer, C W, Francis-West, P
openaire +3 more sources
Molecular characterisation of chondrocytes in autologous chondrocyte implantation
International Journal of Molecular Medicine, 2004Autologous chondrocyte implantation (ACI) relies on the use of cultured cells. However, the biosynthetic profile of cultured chondrocytes is shown to be altered during in vitro expansion. The purpose of this study therefore, was to examine the cellular phenotype of chondrocytes cultured for ACI and to determine the apoptotic index of cells implanted ...
Jiake Xu +6 more
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Expression of FSHR in chondrocytes and the effect of FSH on chondrocytes
Biochemical and Biophysical Research Communications, 2018Chondrocytes express many kinds of hormone receptors. The function of Follicle stimulating hormone (FSH) in the ovary is mediated by FSH receptor (FSHR). FSH receptor (FSHR) is found in many non-ovarian tissues, however it has been unclear if chondrocytes express FSHR.
Guandong Li +9 more
openaire +2 more sources
Arthroscopy: The Journal of Arthroscopic & Related Surgery, 1996
The transplantation of chondrocytes as a treatment to repair defects and degeneration in hyaline articular cartilage is being tested in numerous laboratory and clinical settings. This has included transplanting chondrocytes grown in tissue culture that were procured from non-weight-bearing areas of the affected joint to transplanting allografts with ...
D W, Jackson, T M, Simon
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The transplantation of chondrocytes as a treatment to repair defects and degeneration in hyaline articular cartilage is being tested in numerous laboratory and clinical settings. This has included transplanting chondrocytes grown in tissue culture that were procured from non-weight-bearing areas of the affected joint to transplanting allografts with ...
D W, Jackson, T M, Simon
openaire +2 more sources
Autologous Chondrocyte Implantation
The Journal of Bone & Joint Surgery, 2006Injuries to joint surfaces can result from acute high-impact or repetitive shear and torsional loads to the superficial zone of the articular cartilage architecture. The use of autologous chondrocyte implantation is promising and is associated with several potential long-term benefits.
Jones, D. G., Peterson, L.
openaire +4 more sources
Science Translational Medicine, 2018
An innovative strategy for delivering drugs to chondrocytes in situ offers new avenues for treating osteoarthritis (Geiger et al ., this issue).
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An innovative strategy for delivering drugs to chondrocytes in situ offers new avenues for treating osteoarthritis (Geiger et al ., this issue).
openaire +3 more sources