To reveal and study the structural changes of clusters (mosaic) organization of hyaline cartilage in case of osteoarthritis we carried out experiments on its modeling using bilateral transection of anterior cruciate ligaments in 28 knee joints of 14 ...
Novochadov Valeriy Valeryevich +2 more
doaj +1 more source
Laminins and Nidogens in the Pericellular Matrix of Chondrocytes [PDF]
Boris Schminke +4 more
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Bioprinted Constructs in the Regulatory Landscape: Current State and Future Perspectives
Bioprinting has rapidly emerged as a transformative technology in biomedical research, offering unprecedented potential to replicate complex tissues. Despite its promise, clinical translation remains limited due to regulatory hurdles. This review explores global regulatory frameworks, comparing approaches in the EU, U.S., China, and Australia, and ...
Francesca Perin +6 more
wiley +1 more source
Interplay of Inflammatory Mediators with Epigenetics and Cartilage Modifications in Osteoarthritis
Osteoarthritis (OA), a degenerative disease of diarthrodial joints, is influenced by mechanical and inflammatory factors with aging, obesity, chronic injuries, and secondary diseases thought to be major factors driving the process of articular cartilage ...
Swarna Raman +2 more
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The Space Within: How Architected Voids Promote Tissue Formation
This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou +3 more
wiley +1 more source
Effects of Immune Cells and Cytokines on Different Cells in OA
Pan Luo,* Qiling Yuan,* Xianjie Wan, Mingyi Yang, Peng Xu Department of Joint Surgery, HongHui Hospital, Xi’an Jiaotong University, Xi’an, Shaanxi, 710054, People’s Republic of China*These authors contributed equally to this ...
Luo P, Yuan Q, Wan X, Yang M, Xu P
doaj
T2 and T2* mapping in patients after matrix-associated autologous chondrocyte transplantation: initial results on clinical use with 3.0-Tesla MRI [PDF]
Goetz H. Welsch +7 more
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Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley +1 more source
Cartilage Tissue Engineering Via Icariin and Adipose-derived Stem Cells in Fibrin Scaffold
Background: Nowadays, cartilage tissue engineering is the best candidate for regeneration of cartilage defects. This study evaluates the function of herbal extracts icariin (ICA), the major pharmacological constituent of herba Epimedium, compared with ...
Maryam Bahrami +4 more
doaj +1 more source
Monosodium Urate Crystal-Induced Chondrocyte Death via Autophagic Process [PDF]
Hyun Sook Hwang +3 more
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