Results 141 to 150 of about 171,876 (350)

Immobilized fibrinogen in PEG hydrogels does not improve chondrocyte‐mediated matrix deposition in response to mechanical stimulation [PDF]

, 2006
Orit Schmidt, J. Mizrahi, Jennifer H. Elisseeff, Dror Seliktar   +3 more
openalex   +1 more source

Traceless Regulation of Genetic Circuitry

Advanced Science, EarlyView.
Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley   +1 more source

Characterization of Voltage-Sensitive Calcium Channels in Growth Plate Chondrocytes

, 1997
Michael J. Zuscik, Thomas E. Gunter, J.Edward Puzas, Randy N. Rosier   +3 more
openalex   +1 more source

Runx1 up-regulates chondrocyte to osteoblast lineage commitment and promotes bone formation by enhancing both chondrogenesis and osteogenesis

, 2020
Chen-Yi Tang, Wei Chen, Yuan Luo, Jinjin Wu, Yan Zhang, Abigail McVicar, Matthew McConnell, Yuehua Liu, Hou‐De Zhou, Yiping Li   +9 more
openalex   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

Advanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo, Yingran Shen, Jiaoyu Yi, Juanjuan Li, Ziming Wang, Erji Gao, Siqiang Zheng, Zhe‐Sheng Chen, Bo Tao   +8 more
wiley   +1 more source

Curcuma longa L. extract exhibits anti-inflammatory and cytoprotective functions in the articular cartilage of monoiodoacetate-injected rats

Food & Nutrition Research
Background: Osteoarthritis (OA), the most prevalent form of arthritis, is a degenerative joint disease marked by the progressive deterioration of articular cartilage, leading to clinical manifestations such as joint pain.
Hyelim Kim, Jaeeun Jung, Minhee Lee, Minha Kim, Namgil Kang, Ok-Kyung Kim, Jeongmin Lee   +6 more
doaj   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

151 IKKα AND IKKβ ARE BOTH REQUIRED FOR THE CHEMOTACTIC ACTIVITY OF MONOCYTES TOWARDS PRIMARY OSTEOARTHRITIC CHONDROCYTES

, 2007
Eleonora Olivotto, Rosa Maria Borzı̀, R. Vitellozzi, Stefania Pagani, Angelo Facchini, Flavio Flamigni, Annalisa Astolfi, Luca Cattini, Mariagrazia Uguccioni, Angelo Facchini, Kenneth B. Marcu   +10 more
openalex   +1 more source

Self‐Assembled Myricetin‐Arginine Conjugate Nanozymes for Targeted Suppression of Joint Inflammation and Osteoclastogenesis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Carrier‐free myricetin‐arginine conjugate nanozymes (MANZs) have been fabricated through a Mannich reaction and spontaneous self‐assembly. MANZs selectively accumulate in inflamed joints by targeting M1 macrophages via CAT2‐mediated uptake. The nanozymes can effectively modulate macrophage polarization, suppress osteoclast differentiation, and mitigate
Jiachang Hong, Penghao Ji, Jinxi An, Junchao Huang, Ziheng Bu, Xudong Zhang, Wei Liu, Tingyu Wu, Sen Wang, Wei Zhu, Yuhui Li, Jixian Wan, Sudan Xu, Minfeng Huo, Peng Wu   +14 more
wiley   +1 more source