Results 301 to 310 of about 222,465 (345)

Growth Plate Skeletal Stem Cells and Their Actions Within the Stem Cell Niche. [PDF]

Int J Mol Sci
Cheng NK, Orikasa S, Ono N.
europepmc   +1 more source

From Bioinks to Functional Tissues and Organs: Advances, Challenges, and the Promise of 3D Bioprinting

Macromolecular Materials and Engineering, EarlyView.
This review explores recent advances in 3D bioprinting, emphasizing printing technologies, bioink design, and emerging strategies such as cryogenic printing. Key challenges in biocompatibility, vascularization, and scalability are discussed, alongside opportunities for clinical translation.
Muhammad Wajid Ullah, Mazhar Ul‐Islam, Adeeb Shehzad, Sehrish Manan, Salman Ul Islam, Atiya Fatima, Abdullah Khamis Al‐Saidi, Mustapha El Hariri El Nokab, Juan Quevedo Sanchez, Khaled O. Sebakhy   +9 more
wiley   +1 more source

Role of long non-coding RNAs in cartilage development and osteoarthritis pathogenesis. [PDF]

Eur J Med Res
Sun X, Wang S, Tian J, Li M.
europepmc   +1 more source

Migrasomes, Matrix‐Bound Nanovesicles, and More: Messengers in the Matrix

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) and particles (EPs) are diverse micro‐ and nanoparticles that circulate in bodily fluids and can attach to, or be deposited onto, the extracellular matrix (ECM) and other surfaces. To date, the nomenclature and classification of matrix‐bound or matrix‐associated EVs and EPs (MEVPs) have been unclear, largely due to
Anna V. Kolesov, Natalie Reitz, Marley Dewey, Colin L. Hisey   +3 more
wiley   +1 more source

Targeting VGLL4 maintains extracellular matrix homeostasis and mitigates osteoarthritis in a preclinical model. [PDF]

Nat Commun
Suo J, Wang D, Wang J, Yin X, Hu X, Shao R, Chen S, Sun S, Feng J, Wang L, Feng H, Li Z, Hou W, Zhang L, Chen Y, Zheng X, Wang Z, Zou W.   +17 more
europepmc   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

A Unified Map of Airway Interactions: Secretome and Mechanotransduction Loops from Development to Disease. [PDF]

Adv Respir Med
Tugade C, Ramis J.
europepmc   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Platelet-rich plasma alleviates endoplasmic reticulum stress via the IGF1R-PI3K-AKT pathway in temporomandibular joint osteoarthritis: an in vivo clinical trial. [PDF]

J Transl Med
Liu S, Sun L, Fu J, Cai B, Hao Y.
europepmc   +1 more source

Sustained‐Release Sitagliptin Microneedles for Scar Prevention via Fibroblast‐to‐Adipocyte Conversion

Small Science, EarlyView.
The authors propose a novel use for the conventional hypoglycemic drug, dipeptidyl peptidase IV (DPP4+) inhibitor sitagliptin. Sitagliptin prevents scar formation during wound healing through fibroblast‐to‐adipocyte conversion at least by preventing DPP4‐mediated truncation of IGF‐1.
Ju‐Lei Zhang, Jun‐Nian Zhou, Chao Tang, Yan Li, Wen‐De Yao, Ling‐Li Guo, Zhao‐Yang Chen, Ya‐Li Jia, Quan Zeng, Biao Zhang, Tao Fan, Jia‐Fei Xi, Xue‐Tao Pei, Yan Han, Wen Yue   +14 more
wiley   +1 more source