Results 301 to 310 of about 171,876 (350)
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Science Translational Medicine, 2018
An innovative strategy for delivering drugs to chondrocytes in situ offers new avenues for treating osteoarthritis (Geiger et al ., this issue).
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An innovative strategy for delivering drugs to chondrocytes in situ offers new avenues for treating osteoarthritis (Geiger et al ., this issue).
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Autologous Chondrocyte Transplantation
Clinical Orthopaedics and Related Research, 1999The intrinsic capacity of cartilage to repair chondral injuries is poor. Different techniques to induce cartilage repair with the use of extrinsic chondrogeneic cell sources have been explored in experimental models. Cells can be harvested autologously or as allografts from a healthy part of the donor tissue, isolated, expanded in vitro, and finally ...
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Chondrocyte Isolation and Expansion
2022Chondrocyte isolation requires a combination of enzymatic and mechanical digestion of cartilaginous tissues in order to release the chondrocytes. Extracted primary chondrocytes will then adhere to standard tissue culture plastics, typically in small clusters, over a period of a few days in monolayer culture.
Paul, Harrison +4 more
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In situ chondrocyte viscoelasticity
Journal of Biomechanics, 2012It has been proposed, based on theoretical considerations, that the strain rate-dependent viscoelastic response of cartilage reduces local tissue and cell deformations during cyclic compressions. However, experimental studies have not addressed the in situ viscoelastic response of chondrocytes under static and dynamic loading conditions. In particular,
Sang-Kuy, Han +3 more
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Prevention of Chondrocyte Apoptosis
The Journal of Bone and Joint Surgery-American Volume, 2001The occurrence of chondrocyte apoptosis may be critical in determining the extent of a lesion and subsequent repair after mechanical injury to articular cartilage. Agents that prevent apoptosis and increase chondrocyte survival may prove beneficial in the treatment of these lesions.
D D, D'Lima +4 more
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Tissue Engineering with Chondrocytes
Facial Plastic Surgery, 2002Tissue engineering of cartilage, using chondrocytes based on the use of synthetic biodegradable polymer cell delivery vehicles (scaffolds), is an alternate treatment modality for replacing missing cartilage. Cartilage tissue engineering has an important role to play in the generation of graft material for head and neck reconstruction. It is an approach
R James, Koch, Goutham Krishna, Gorti
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Transplantation of Isolated Chondrocytes
Clinical Orthopaedics and Related Research, 1991Intramuscular transplantation of isolated syngeneic chondrocytes from hyaline and elastic cartilage results in formation of cartilage with various degrees of similarity to the original tissue. Cells from cartilage with a simple structure, such as nasal septal cartilage, form islands of tissue with flattened chondrocytes at the periphery and more ...
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2014
Bir çok insanı etkileyen eklem hasarındaki temel sorun, yüksek oranda diferansiye olmuş, vasküler kan desteği eksik ve yalnızca sınırlı rejenerasyon kabiliyetine sahip olan erişkin eklem kıkırdağıdır. Femorotibial eklem yüzeyindeki osteokondral defektlerinin tamirinde son zamanlarda ilginin arttığı çok ümit verici bir yöntem ise orolog kondrosit ...
YİLDİZ, Cemil +7 more
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Bir çok insanı etkileyen eklem hasarındaki temel sorun, yüksek oranda diferansiye olmuş, vasküler kan desteği eksik ve yalnızca sınırlı rejenerasyon kabiliyetine sahip olan erişkin eklem kıkırdağıdır. Femorotibial eklem yüzeyindeki osteokondral defektlerinin tamirinde son zamanlarda ilginin arttığı çok ümit verici bir yöntem ise orolog kondrosit ...
YİLDİZ, Cemil +7 more
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