Results 291 to 300 of about 231,673 (393)

Chondrocyte death in canine osteochondral explants exposed to 0.5 percent bupivacaine

, 2009
Geoffrey S. Hennig
openalex   +2 more sources

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Mechanisms of active metabolites from traditional Chinese medicine in osteoarthritis: a critical review. [PDF]

Front Pharmacol
Li H, Zhao Y, Qi P, Zhang B, Ma J, Xie X, Li N.   +6 more
europepmc   +1 more source

Mechanisms directing chondrocyte specification in the developing limb

, 2018
Jacqueline L. Norrie
openalex   +2 more sources

Metabolic engineering of adipose‐derived stem cell exosomes via arachidonic acid potentiates diabetic wound repair by orchestrating angiogenesis: A multi‐omics guided strategy

VIEW, EarlyView.
AA‐Exos promotes angiogenesis and accelerates diabetic wound healing by activating the PI3K/AKT/mTOR pathway. Abstract Diabetic wounds are common and challenging complications of diabetes, characterized by delayed healing and an increased risk of infection.
Yujiao Cai, Jinnan Wang, Yan Liu, Xiaoke Zhu, Zhanyuan Yuan, Weiling Li, Dehui Che, Dongsheng Cao   +7 more
wiley   +1 more source

Dkk1 inhibition restores mandibular growth in an achondroplasia mouse model. [PDF]

Biol Open
Raveendranathan B, Estibals V, Pulido E, Lemoine C, Kaci N, Pereur R, Zarhrate M, Dupichaud S, Dambroise E, Legeai-Mallet L, Biosse Duplan M.   +10 more
europepmc   +1 more source

Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies

VIEW, EarlyView.
This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li, Yulan Liu, Yuran Li, Yingjie Hua, Xinquan Jiang, Mingliang Zhou   +5 more
wiley   +1 more source

Microenvironmental stiffness directs microtubule perturbation in chondrocyte mitosis via ILK-refilinB/Smad3 axis. [PDF]

Bone Res
Duan M, Zhou C, Su G, Zhang C, Ren J, Chi Q, Liu X, Yang L, Bai H, Zeng YC, Kim S, Zhai Y, Oh CY, Ye AY, Chen Y, Si L, Liu X, Xie J.   +17 more
europepmc   +1 more source

Contribution du gène "Ank" dans la balance PPi/Pi et dans le maintien du phénotype du chondrocyte articulaire

, 2009
F. Cailotto
openalex   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

Andrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz, Wioletta Lech, Anna Figiel‐Dabrowska, Marta Kot, Magdalena Murzyn, Natalia Malawska, Barbara Pienkowska‐Grela, Zuzanna Sandowska‐Markiewicz, Iwona Ziolkowska‐Suchanek, Agnieszka Zimna, Tomasz Oldak, Natalia Rozwadowska, Anna Sarnowska   +12 more
wiley   +1 more source