Results 241 to 250 of about 21,815 (286)
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Matrix Biology, 1993
Monoclonal antibodies have been developed that recognize epitopes in native chondroitin sulfate chains. One of these antibodies, CS-56, reportedly recognizes chondroitin 4- and 6-sulfates. However, this antibody, and four other anti-chondroitin sulfate antibodies, 4C3, 4D3, 6C3 and 7D4, do not recognize epitopes in chondroitin sulfate chains from Swarm
J Michael Sorrell +2 more
exaly +3 more sources
Monoclonal antibodies have been developed that recognize epitopes in native chondroitin sulfate chains. One of these antibodies, CS-56, reportedly recognizes chondroitin 4- and 6-sulfates. However, this antibody, and four other anti-chondroitin sulfate antibodies, 4C3, 4D3, 6C3 and 7D4, do not recognize epitopes in chondroitin sulfate chains from Swarm
J Michael Sorrell +2 more
exaly +3 more sources
Isomeric Chondroitin Sulphates
Nature, 1958A RECENT communication1 claims to “confirm Meyer's hypothesis that chondroitin sulphates A and C are only two fractions of the same polydisperse substance”. Apparent lack of agreement in nomenclature2–4 further emphasizes the need for clear differentiation of the isomeric chondroitin sulphates of connective tissue.
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The Journal of Biochemistry, 1979
By heating the pyridinium salts of chondroitin 4- and 6-sulfates in dimethyl sulfoxide containing 10% of water or methanol at 80 degrees C for 1--5 h, several chondroitin preparations with sulfur contents of 0.02--1.05% were prepared in 83--96% yields, respectively.
K, Nagasawa, Y, Inoue, T, Tokuyasu
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By heating the pyridinium salts of chondroitin 4- and 6-sulfates in dimethyl sulfoxide containing 10% of water or methanol at 80 degrees C for 1--5 h, several chondroitin preparations with sulfur contents of 0.02--1.05% were prepared in 83--96% yields, respectively.
K, Nagasawa, Y, Inoue, T, Tokuyasu
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Journal of Molecular Structure: THEOCHEM, 2004
Abstract Molecular modeling of glycosaminoglycans, hyaluronan, chondroitin, chondroitin-4-sulfate, chondroitin-6-sulfate and keratan sulfate is presented. Semiempirical quantum mechanical calculations, PM3 method, have been used to locate the minimal energy regions in the conformational space around the β 1→3 and β 1→4 glycosidic linkages. The global
Halil Bayraktar +3 more
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Abstract Molecular modeling of glycosaminoglycans, hyaluronan, chondroitin, chondroitin-4-sulfate, chondroitin-6-sulfate and keratan sulfate is presented. Semiempirical quantum mechanical calculations, PM3 method, have been used to locate the minimal energy regions in the conformational space around the β 1→3 and β 1→4 glycosidic linkages. The global
Halil Bayraktar +3 more
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Biosynthesis of Chondroitin Sulphates
Nature, 1959LITTLE information is available regarding the biosynthesis of acid mucopolysaccharides. Knowledge of biosynthetic pathways to the chondroitin sulphates in particular is practically confined to the fact that glucose is utilized for both the hexosamine and uronic acid moieties1 and that 3′—phosphoadenosine 5′—phosphosulphate (PAPS) is involved in ...
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Sequential synthesis of chondroitin oligosaccharides by immobilized chondroitin polymerase mutants
Glycoconjugate Journal, 2008Escherichia coli strain K4 expresses a chondroitin (CH)-polymerizing enzyme (K4CP) that contains two glycosyltransferase active domains. K4CP alternately transfers glucuronic acid (GlcA) and N-acetyl-galactosamine (GalNAc) residues using UDP-GlcA and UDP-GalNAc donors to the nonreducing end of a CH chain acceptor.
Nobuo, Sugiura +5 more
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Chondroitin Product Selection for the Glucosamine/Chondroitin Arthritis Intervention Trial
Journal of the American Pharmacists Association: JAPhA, 2006To select a high-quality chondroitin dosage form and/or an appropriate source of sodium chondroitin for the National Institutes of Health's Glucosamine/Chondroitin Arthritis Intervention Trial (GAIT).Controlled experimental trials.Laboratory.Not applicable.Commercially available chondroitin products were reviewed, and purified sodium chondroitin from ...
Jamie G, Barnhill +5 more
exaly +3 more sources
The Journal of Organic Chemistry, 2019
Chondroitin sulfate (CS) is a structurally complex polyanionic glycosaminoglycan that plays essential roles in physiological processes. Here we report a facile approach to a library of CS tetra- and hexasaccharides based on the enzymatic degradation of chondroitin over 10 or 11 steps, which is the shortest synthetic route toward size-defined CS ...
Xiao Zhang +4 more
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Chondroitin sulfate (CS) is a structurally complex polyanionic glycosaminoglycan that plays essential roles in physiological processes. Here we report a facile approach to a library of CS tetra- and hexasaccharides based on the enzymatic degradation of chondroitin over 10 or 11 steps, which is the shortest synthetic route toward size-defined CS ...
Xiao Zhang +4 more
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Journal of Consumer Health On the Internet, 2006
Results of the four-year study entitled the Glucosamine/ chondroitin Arthritis Intervention Trial (GAIT) provided partial answers to those seeking relief from arthritis pain. Scientists will continue studying the efficacy of these substances as pain remedy and cartilage rejuvenator.
Suzanne M. Shultz, Esther Y. Dell
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Results of the four-year study entitled the Glucosamine/ chondroitin Arthritis Intervention Trial (GAIT) provided partial answers to those seeking relief from arthritis pain. Scientists will continue studying the efficacy of these substances as pain remedy and cartilage rejuvenator.
Suzanne M. Shultz, Esther Y. Dell
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Biosynthesis of chondroitin sulfate. Assembly of chondroitin on microsomal primers
Biochemistry, 1973M E, Richmond, S, DeLuca, J E, Silbert
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