Results 101 to 110 of about 77,038 (354)

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Diabetes Results in Structural Alteration of Chondroitin Sulfate in the Urine

Journal of Pharmacy & Pharmaceutical Sciences, 2013
Purpose. The assessment of the clinical significance of chondroitin sulfate in patients with type 2 diabetes mellitus (T2DM) and diabetic nephropathy (DN) for the detection of the relationship between chondroitin sulfate (CS) structure and disease ...
Tingting Zhao, Xiaoguang Lu, Neal M Davies, Yuewen Gong, Jingzhen Guo, Haojun Zhang, Zhiguo Li, Jing Hong, Guixiang Fu, Ping Li   +9 more
doaj   +1 more source

Dendrobium Officinale‐Derived Carbon Dots Nanozymes Alleviate Colitis by Orchestrating Intestinal Mucus‐Epithelium‐Immune Barriers

Advanced Science, EarlyView.
Dendrobium officinale‐derived carbon dots (DO‐CDs) exhibiting enzyme‐mimetic activities are synthesized via a hydrothermal approach. In the colitis model, DO‐CDs effectively facilitated the repair of mucosal, epithelial, and immune barriers by upregulating the expression of mucins and tight junction proteins, as well as re‐establishing intestinal ...
Chenxi Xu, Xiaoling Huang, Zhichao Deng, Ruiying Wang, Seyedalireza Ghazimirsaeid, Li Yao, Yuanyuan Zhu, Bowen Gao, Junlong Fu, Mingxin Zhang, Mei Yang, Mingzhen Zhang   +11 more
wiley   +1 more source

Future directions for the management of pain in osteoarthritis. [PDF]

, 2014
Osteoarthritis (OA) is the predominant form of arthritis worldwide, resulting in a high degree of functional impairment and reduced quality of life owing to chronic pain. To date, there are no treatments that are known to modify disease progression of OA
Aigner T, Anasuya Kuttapitiya, Balanescu AR, Bannuru RR, Chou R, da Costa BR, Danielsson L, Fanelli A, Fransen M, Haviv B, Huskisson EC, Lim YZ, Mankin HJ, McAlindon TE, Merlotti D, Nguyen US, Nidhi Sofat, Pelletier JP, Sagar DR, Sellers RS, Sofat N, Tannenbaum H, Wajed J, Wakitani S   +23 more
core   +1 more source

Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined

Aggregate, EarlyView.
Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei, Xikai Wang, Zhuang Hu, Jierui Yan, Xiaobo Wang, Haoran Wang, Ya Hou, Pengfei Zhang, Qihang Ding   +8 more
wiley   +1 more source

Photorefractive keratectomy: measuring the matrix metalloproteinase activity and chondroitin sulfate concentration in tear fluid

Clinical Ophthalmology, 2010
Tetsuya Mutoh, Masaya Nishio, Yukihiro Matsumoto, Kiyomi Arai, Makoto ChikudaDepartment of Ophthalmology, Dokkyo Medical University Koshigaya Hospital, Saitama, JapanAbstract: We herein report the case of a 20-year-old man who underwent a photorefractive
Tetsuya Mutoh, Masaya Nishio, Yukihiro Matsumoto, et al   +3 more
doaj  

Showiness or efficiency: what to choose?

Patologìâ, 2013
BACKGROUND: Osteoarthritis is a leading cause of disability in the world. Current treatment focuses on symptom relief and improving a patient's overall function.
D.G. Rekalov, B.B. Samura, R.L. Kulinich, M.P. Kras’ko, N.I. Kargals’ka, V.V. Brylyova   +5 more
doaj   +1 more source

Efficacy and safety of prednisolone and chloroquine Add on therapy in osteoarthritis of the knee treated with fixed Dose combination of Glucosamine and chondroitin sulfate [PDF]

Background & ObjectiveOsteoarthritis is the most common type of joint disorder and also the main reason to consult Rheumatologists. Furthermore, a high level of weakness especially among elderly is due to OA.
بهلولی, شهاب, جستان, مارینا, قربانی, مریم   +2 more
core  

Nanostructured 3D Constructs Based on Chitosan and Chondroitin Sulphate Multilayers for Cartilage Tissue Engineering [PDF]

, 2013
Nanostructured three-dimensional constructs combining layer-by-layer technology (LbL) and template leaching were processed and evaluated as possible support structures for cartilage tissue engineering.
AM Martins, AR Fajardo, BC Heng, C Albrecht, C Chung, C Detzel, C Kirkpatrick, C Vinatier, Clemens A. Van Blitterswijk, D Puppi, E Miranda, EJ Menzel, FH Chen, FT Moutos, GV Martins, H Fan, J Almodo?var, JF Mano, JF Mano, JF Piai, JK Francis Suh, JM Sobral, JM Varghese, Joana M. Silva, João F. Mano, JRE Fraser, JS Mao, JS Pieper, JS Temenoff, K Anselme, K Köhler, K Von Der Mark, L Wu, L-P Yan, L-P Yan, M Kubo, Marcel Karperien, MV Voinova, Mário A. Barbosa, Nicole Georgi, NM Alves, O Franke, P Sher, Praveen Sher, R Jin, R Servaty, RG LeBaron, RR Costa, RR Costa, Rui Costa, Rui L. Reis, S Chatterjee, S Ghosh, S-H Lee, SC Neves, T Boudou, T Crouzier, W Sui, W-C Chen, WH Dietmar, Y Gong, Y Liu, Z Tang   +62 more
core   +4 more sources

Chondroitin Sulfate is the Primary Receptor for a Peptide-Modified AAV That Targets Brain Vascular Endothelium In Vivo

Molecular Therapy: Nucleic Acids, 2014
Recently, we described a peptide-modified AAV2 vector (AAV-GMN) containing a capsid-displayed peptide that directs in vivo brain vascular targeting and transduction when delivered intravenously.
James C Geoghegan, Nicholas W Keiser, Anna Okulist, Inês Martins, Matthew S Wilson, Beverly L Davidson   +5 more
doaj   +1 more source