Tissue‐Resident Macrophage in Inflammation and Cancer
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang +13 more
wiley +1 more source
Quantitative LC-MS/MS profiling reveals aberrant chondroitin sulfate in Alzheimer's disease. [PDF]
Xu Y +10 more
europepmc +1 more source
ECM, extracellular matrix; BDNF, brain‐derived neuroptrophic factor; FGF, fibroblast growth factor; VEGF, vascular endothelial growth factor. Abstract Heparan sulfate, a structurally diverse glycosaminoglycan that is abundant in the central nervous system (CNS), orchestrates essential processes fundamental to neural plasticity, neurorepair, and ...
Mozammel H. Bhuiyan +3 more
wiley +1 more source
Chondroitin Sulfate Proteoglycans in CNS Development and Pathophysiology. [PDF]
Hosseini SM, Karimi-Abdolrezaee S.
europepmc +1 more source
ABSTRACT In the central nervous system (CNS), the tissue microenvironment is continuously monitored and regulated to secure the unobstructed function of neurons and of their networks. This is a key function of the neurovascular niche (NVN), which is the interface between the cells of the nervous tissue and the cells and the content of blood vessels. It
Ilias Kazanis +4 more
wiley +1 more source
Fabrication of Chondroitin Sulfate-Copper/Zinc Complexes and Antibacterial Activity Involving Hydrogel Application in Infected Wound Healing. [PDF]
Shen Q +7 more
europepmc +1 more source
Epigenetic Changes Associated With a Phenotypic Transition in Namibian Cheetahs
ABSTRACT In populations with low genetic diversity, the capacity to adapt to environmental change is limited. While epigenetic mechanisms can generate phenotypic plasticity, their role in mediating adaptive life‐history transitions in the wild is largely unknown.
Colin Vullioud +6 more
wiley +1 more source
Coarse-Grained Martini 3 Model of Chondroitin Sulfate A. [PDF]
Greicius P +3 more
europepmc +1 more source
Chondroitin sulfate modulates gut microbiota to improve bone metabolism and reduce locomotion problems in yellow-feathered broilers. [PDF]
Xue Y +10 more
europepmc +1 more source
High Humidity Exacerbates Rheumatoid Arthritis in Mice via <i>Prevotella stercorea</i>-Mediated Chondroitin Sulfate Degradation. [PDF]
Wang M +7 more
europepmc +1 more source

