Results 181 to 190 of about 38,338 (212)

Biosynthesis and function of chondroitin sulfate

Biochimica et Biophysica Acta (BBA) - General Subjects, 2013
Chondroitin sulfate proteoglycans (CSPGs) are principal pericellular and extracellular components that form regulatory milieu involving numerous biological and pathophysiological phenomena. Diverse functions of CSPGs can be mainly attributed to structural variability of their polysaccharide moieties, chondroitin sulfate glycosaminoglycans (CS-GAG ...
Tadahisa, Mikami, Hiroshi, Kitagawa
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Conjugation of chondroitin sulfates with amines

Russian Journal of Bioorganic Chemistry, 2008
Conjugation of chondroitin sulfates with pharmacologically important amines in a water medium in the presence of 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide was studied. Conjugates with amide and isoureidocarbonyl groups were synthesized.
I Iu, Ponedel'kina, V N, Odinokov, E S, Lukina, U M, Dzhemilev   +3 more
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Chondroitin Sulfate in Osteoarthritis Therapy

Orthopedics, 2009
Despite the news of aid from chondroitin sulfate, recent research has questioned its efficacy in treating osteoarthritis.
Jonathan D, Morris, Kelly M, Smith
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In Vitro Effects of Chondroitin Sulfate

2006
Publisher Summary A number of in vitro studies have been performed to determine the mode of action of chondroitin sulfate (CS). It has been demonstrated that CS possesses both anabolic effects on cartilage metabolism and anticatabolic properties. In various models of cartilage culture or of isolated chondrocytes, CS has demonstrated the capacity to ...
A, Fioravanti, G, Collodel
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Antioxidant Activity of Chondroitin Sulfate

2006
Publisher Summary Molecules in biological systems often perform more than one function. Many structures have the ability to scavenge free radicals, acting in living organisms as antioxidants, although their main biological function is different. During oxidative stress, the increase in the concentration of these molecules seems to be a biological ...
G M, Campo, A, Avenoso, S, Campo, A M, Ferlazzo, A, Calatroni   +4 more
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Isolation and Purification of Chondroitin Sulfate

2006
Publisher Summary This chapter discusses methods for the isolation and purification of chondroitin sulfate (CS). This molecule is a sulfated glycosaminoglycan (GAG) composed of a linear polysaccharide chain with repeating disaccharides of defined structures that usually contain one hexosamine, one hexuronic acid, and a sulfate ester.
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Immunology of Chondroitin/Dermatan Sulfate

1995
Variable substitutions and locations of the sulfate esters along the backbone of chondroitin/dermatan sulfate chains, combined with their carbohydrate structures, present topographies to immune systems which can be recognized as antigenic. This has led to the development of a number of monoclonal antibodies which recognize distinct epitopes in the ...
V C, Hascall, R J, Midura, J M, Sorrell, A H, Plaas   +3 more
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Chondroitin Sulfate and RBC Clumping

Archives of Ophthalmology, 1984
To the Editor. —Chondroitin sulfate is a new viscoelastic substance that is advocated as a protective agent for intraocular lens insertion. Chondroitin sulfate has been shown to be more effective in protecting the endothelium of animal and human corneas than other substances.1Contact of intraocular lenses with endothelium causes endothelial damage and
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Chondroitin Sulfate

2011
Angela Zimmerman, Michael F. Roizen
  +4 more sources

Degradation of Chondroitin Sulfate and Dermatan Sulfate with Chondroitin Lyases

2003
M J, Hernáiz, R J, Linhardt
openaire   +2 more sources