Results 271 to 280 of about 77,038 (354)

Recent Advances in Injectable Hydrogel Biotherapeutics for Regenerative Dental Medicine

Macromolecular Bioscience, Volume 25, Issue 10, October 2025.
This review analyses multifunctional injectable hydrogels, natural or synthetic, physically or chemically crosslinked, that deliver exosomes, stem cells, and other bioactive cues to inflamed or damaged oral tissues. We discuss their immunomodulatory, antimicrobial, angiogenic, and osteogenic capacities, highlighting advances that enable regenerative ...
Renan Dal‐Fabbro, Arwa Daghrery, Caroline Anselmi, Igor Paulino M. Soares, Alexandre Henrique dos Reis‐Prado, Pedro Henrique Chaves de Oliveira, Marco C. Bottino   +6 more
wiley   +1 more source

Sequential Targeting Chondroitin Sulfate-Bilirubin Nanomedicine Attenuates Osteoarthritis via Reprogramming Lipid Metabolism in M1 Macrophages. [PDF]

Adv Sci (Weinh)
Deng C, Xiao Y, Zhao X, Li H, Chen Y, Ai K, Jiang T, Wei J, Chen X, Lei G, Zeng C.   +10 more
europepmc   +1 more source

Amyloid precursor-like protein 2 (APLP2) is modified by the addition of chondroitin sulfate glycosaminoglycan at a single site.

, 1994
Gopal Thinakaran, Sangram S. Sisodia
openalex   +1 more source

Heart Regeneration and Repair: Molecular Mechanism and Therapeutic Targets

MedComm, Volume 6, Issue 10, October 2025.
Regarding the general picture of heart regeneration therapy, it encompasses exogenous cell therapy, endogenous medications, metabolism, interventions in gene pathways, as well as the therapeutic strategies in the burgeoning interdisciplinary field of medicine and engineering in recent years.
Mingchuan Liu, Tingwei Peng, Rui Yu, Kexin Wang, Di Wang, Xiaojie Jia, Yan Zhang, Jianqiang Hu, Bingchao Qi, Yan Li   +9 more
wiley   +1 more source

Alone or in combination, hyaluronic acid and chondroitin sulfate alleviate ECM degradation in osteoarthritis by inhibiting the NF-κB pathway. [PDF]

J Orthop Surg Res
Ma Y, Yang X, Jiang M, Ye W, Qin H, Tan S.   +5 more
europepmc   +1 more source

Hydrogel Microspheres as Versatile Platforms for Biomedical Research: Design, Properties, and Applications

MedComm, Volume 6, Issue 10, October 2025.
Schematic diagram illustrating the comprehensive landscape of hydrogel microspheres (HMs). (A) The components of HMs. (B) Preparation technologies employed in fabricating HMs. (C) The diverse applications of HMs across different fields. (D) The therapeutic applications of HMs in the treatment of various systemic diseases, demonstrating their potential ...
Meng Yang, Yuanyuan Shi, Feng Wang, Xin Zhang, Jiayi Shao, Fan Yang, Hao Sun, Chong Zhang, Zheng Zhou, Jianyong Huang, Pengyu Lv, Patrick Shu‐Hang Yung, Jin Cheng, Hong‐Jie Huang, Jian‐Quan Wang   +14 more
wiley   +1 more source

Porcine-Derived Chondroitin Sulfate Sodium Alleviates Osteoarthritis in HTB-94 Cells and MIA-Induced SD Rat Models. [PDF]

Int J Mol Sci
Kim H, Kim J, Park SH, Kim J, Gwon Y, Lee M, Park SJ.   +6 more
europepmc   +1 more source

Molecular Evolution and Gene Diversity of Dermatan Sulfate Sulfotransferases in Ascidians

Proteoglycan Research, Volume 3, Issue 4, October 2025.
ABSTRACT Ascidians (Chordata, Tunicata) are model organisms for studying molecules, particularly sulfated glycosaminoglycans (GAGs), due to their phylogenetic proximity to vertebrates and unique GAG variants. Over‐sulfated dermatan sulfate (DS) contributes to proteoglycan diversity and cellular processes in metazoans.
Vanessa de Sousa Rizzo‐Valente, Mauro S. G. Pavão   +1 more
wiley   +1 more source

A dual role for pleiotrophin in modulating inflammation and myelination in the presence of chondroitin sulfate proteoglycans after nervous system injury. [PDF]

Front Cell Neurosci
Gupta SJ, Churchward MA, Todd KG, Winship IR.   +3 more
europepmc   +1 more source

The Glycosaminoglycan‐Dependent Interactome of Neurexin‐1 in Human Fetal Glial Cells

Proteoglycan Research, Volume 3, Issue 4, October 2025.
ABSTRACT Neurexins are synaptic adhesion molecules best characterized in neurons, where they regulate synapse assembly and function, with emerging evidence indicating they are also abundantly expressed by astrocytes. To elucidate the interactome of NRXN1α, we employed a proximity labeling strategy in cultured human fetal glial cells (SVG p12 cells ...
Meg Critcher, Han Wu, Yajing Lu, Mia L. Huang   +3 more
wiley   +1 more source