Holothurian Fucosylated Chondroitin Sulfate [PDF]
Marine Drugs, 2014 Fucosylated chondroitin sulfate (FucCS) is a structurally distinct glycosaminoglycan found in sea cucumber species. It has the same backbone composition of alternating 4-linked glucuronic acid and 3-linked N-acetyl galactosamine residues within disaccharide repeating units as regularly found in mammalian chondroitin sulfates.
Vitor Pomin, Vitor H. Pomin
core +5 more sources
Fucosylated Chondroitin Sulfates with Rare Disaccharide Branches from the Sea Cucumbers Psolus peronii and Holothuria nobilis: Structures and Influence on Hematopoiesis. [PDF]
Pharmaceuticals (Basel), 2023 Two fucosylated chondroitin sulfates were isolated from the sea cucumbers Psolus peronii and Holothuria nobilis using a conventional extraction procedure in the presence of papain, followed by anion-exchange chromatography on DEAE-Sephacel.
Ustyuzhanina NE +12 more
europepmc +3 more sources
Low-Molecular-Weight Chondroitin Sulfates Alleviate Simulated Microgravity-Induced Oxidative Stress and Bone Loss in Mice. [PDF]
Curr Issues Mol Biol, 2023 (1) Background: Many studies have shown that microgravity experienced by astronauts or long-term bedridden patients results in increased oxidative stress and bone loss.
Lan R +6 more
europepmc +3 more sources
Revista Brasileira de Zootecnia, 2020 We aimed to evaluate the performance, nutrient digestibility, and intestinal histomorphometry of broilers fed diet supplemented with chondroitin sulfate and glucosamine sulfate. The experiment was carried out with 320 male broiler chicks distributed in a
Café, Marcos Barcellos +7 more
core +3 more sources
Molecular Dynamics-Based Comparative Analysis of Chondroitin and Dermatan Sulfates
Biomolecules, 2023 Glycosaminoglycans (GAGs) are a class of linear anionic periodic polysaccharides containing disaccharide repetitive units. These molecules interact with a variety of proteins in the extracellular matrix and so participate in biochemically crucial ...
Sergey A. Samsonov, Marta Pągielska
core +2 more sources
Conformational analysis of the oligosaccharides related to side chains of holothurian fucosylated chondroitin sulfates. [PDF]
Mar Drugs, 2015 Anionic polysaccharides fucosylated chondroitin sulfates (FCS) from holothurian species were shown to affect various biological processes, such as metastasis, angiogenesis, clot formation, thrombosis, inflammation, and some others.
Gerbst AG +3 more
europepmc +3 more sources
Structural basis for human chondroitin sulfate chain polymerization. [PDF]
Nat CommunChondroitin sulfates are complex polysaccharide chains that regulate various biological processes at the cell surface and within the extracellular matrix.
Dutta P +11 more
europepmc +3 more sources
Chondroitin sulfates in the developing rat hindbrain confine commissural projections of vestibular nuclear neurons. [PDF]
Neural Dev, 2012 BACKGROUND: Establishing correct neuronal circuitry is crucial to proper function of the vertebrate nervous system. The abundance of chondroitin sulfate (CS) proteoglycans in embryonic neural environments suggests that matrix proteoglycans regulate ...
Kwok JC +6 more
europepmc +4 more sources
Structural elucidation of fucosylated chondroitin sulfates from sea cucumber using FTICR-MS/MS. [PDF]
Eur J Mass Spectrom (Chichester), 2018 European Journal of Mass Spectrometry, 24, 157–167Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY.
Agyekum I +7 more
europepmc +2 more sources
Fucosylated Chondroitin Sulfates from the Sea Cucumbers Paracaudina chilensis and Holothuria hilla: Structures and Anticoagulant Activity. [PDF]
Mar Drugs, 2020 Fucosylated chondroitin sulfates (FCSs) PC and HH were isolated from the sea cucumbers Paracaudina chilensis and Holothuria hilla, respectively. The purification of the polysaccharides was carried out by anion-exchange chromatography on a DEAE-Sephacel ...
Ustyuzhanina NE +7 more
europepmc +2 more sources