Evaluation of an Amniotic Membrane-Collagen Dermal Substitute in the Management of Full-Thickness Skin Defects in a Pig [PDF]
Background To minimize the inflammatory reaction and improve healing, a new modified dermal substitute composed of an atelocollagen, chondroitin-6-sulfate, and amniotic membrane (AM) was applied to full-thickness skin defects in a pig. Atelocollagen was
Hyunji Kim +6 more
doaj +2 more sources
Preparation and purification of Flavobacterium heparinum chondroitinases AC and B by hydrophobic interaction chromatography [PDF]
Flavobacterium heparinum is a soil bacterium that produces several mucopolysaccharidases such as heparinase, heparitinases I and II, and chondroitinases AC, B, C and ABC. The purpose of the present study was to optimize the preparation of F.
Aguiar, Jair Adriano Kopke +1 more
core +1 more source
Molecular effects of chondroguard in osteoarthritis and herniated discs
Chondroitin sulfates (CS) are a building material for the cartilage and have anti-inflammatory and antioxidant effects. The paper gives the results of analyzing the pharmaceutical composition of chondroguard and its pharmaceutical substance CS-BIOACTIVE (
A. M. Lila +4 more
doaj +1 more source
The importance of biomarkers to predict recovery following total hip arthroplasty (THA) is still unclear to clinicians. To assess the preoperative biomarkers of patients with pseudoarthrosis of the femoral neck and their dynamics in the early ...
S. E. Bondarenko +5 more
doaj +1 more source
Comparative study of osteogenic activity of multilayers made of synthetic and biogenic polyelectrolytes [PDF]
Polyelectrolyte multilayer (PEM) coatings on biomaterials are applied to tailor adhesion, growth, and function of cells on biomedical implants. Here, biogenic and synthetic polyelectrolytes (PEL) are used for layer-by-layer assembly to study the ...
Gonzalez-Garcia, Cristina +4 more
core +1 more source
Semi-synthesis of chondroitin sulfate-E from chondroitin sulfate-A [PDF]
Chondroitin sulfate-E (chondroitin-4, 6-disulfate) was prepared from chondroitin sulfate-A (chondroitin-4 - sulfate) by regioselective sulfonation, performed using trimethylamine sulfur trioxide in formamide under argon. The structure of semi-synthetic chondroitin sulfate-E was analyzed by PAGE, (1)H NMR, (13)C NMR, 2D NMR and disaccharide analysis and
Chao, Cai +6 more
openaire +2 more sources
Transdermal permeability of N-Acetyl-D-Glucosamine [PDF]
Transdermal permeation of N-acetyl-D-glucosamine (NAG), a metabolite of glucosamine was examined. Glucosamine salts are nutraceuticals used in the oral treatment of osteoarthritis. Sparse information is available regarding glucosamine and NAG transdermal
Achmed, Hishamaldin +4 more
core +1 more source
Intravesical Sodium Chondroitin Sulphate to Treat Overactive Bladder: Preliminary Result [PDF]
Purpose: This study aimed to verify the efficacy and safety of intravesical treatment with sodium chondroitin sulfate (CS) in patients with overactive bladder (OAB) who are refractory to previous antimuscarinic treatment.
Lokman Irkilata +5 more
doaj +1 more source
Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type. [PDF]
Amyloid aggregates found in the brain of patients with neurodegenerative diseases, including Alzheimer's and Parkinson's disease, are thought to spread to increasingly larger areas of the brain through a prion-like seeding mechanism.
Esko, Jeffrey D +5 more
core +2 more sources
Marine organism sulfated polysaccharides exhibiting significant antimalarial activity and inhibition of red blood cell invasion by Plasmodium [PDF]
The antimalarial activity of heparin, against which there are no resistances known, has not been therapeutically exploited due to its potent anticoagulating activity.
Fernàndez Busquets, Xavier +3 more
core +1 more source

