Cell Reports, 2016 The basement membrane is crucial for cell polarity, adhesion, and motility, but how it is assembled on the cell surface remains unclear. Here, we find that ablation of glycosaminoglycan (GAG) side chains of proteoglycans in the neuroretina disrupts the ...
Chenqi Tao, Xin Zhang
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Glycosaminoglycans – types, structure, functions, and the role in wound healing processes
Annales Academiae Medicae Silesiensis, 2023 Glycosaminoglycans (GAGs) are a group of heteropolysaccharides, which include: chondroitin sulfates, dermatan sulfates, heparan sulfates, heparin, keratan sulfates, and hyaluronic acid.
Kinga Orlińska +4 more
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Preparation of Low Molecular Weight Chondroitin Sulfates, Screening of a High Anti-Complement Capacity of Low Molecular Weight Chondroitin Sulfate and Its Biological Activity Studies in Attenuating Osteoarthritis. [PDF]
Int J Mol Sci, 2016 Li L +7 more
europepmc +2 more sources
Horizontal gene transfer contributed to the evolution of extracellular surface structures [PDF]
, 2012 The single-cell layered ectoderm of the fresh water polyp Hydra fulfills the function of an epidermis by protecting the animals from the surrounding medium.
Altstätter, Johannes +13 more
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Bolʹ, Sustavy, Pozvonočnik, 2022 Background. Bone health is relevant for patients of all age groups. Special attention is paid to childhood and adolescence, since it is during this period that bone mass is actively accumulated, which depends on the structural and functional state of the
T.V. Frolova +6 more
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Mast cell clones: a model for the analysis of cellular maturation. [PDF]
, 1982 Cloned mouse mast cells resemble, by ultrastructure, immature mast cells observed in vivo. These mast cell clones can be grown in the absence of any other cells, facilitating direct investigations of their biochemistry and function.
Cantor, H +10 more
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The effect of increasing the sulfation level of chondroitin sulfate on anticoagulant specific activity and activation of the kinin system. [PDF]
PLoS ONE, 2018 Oversulfated chondroitin sulfate (OSCS) was identified as a contaminant in certain heparin preparations as the cause of adverse reactions in patients. OSCS was found to possess both plasma anticoagulant activity and the ability to activate prekallikrein ...
J Hogwood +6 more
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Demonstration of chondroitin sulfates degrading endo-β-glucuronidase activity in rabbit liver [PDF]
, 1985 Reduced chondroitin sulfate was incubated with rabbit liver extracts followed by reduction once more with sodium [3H]borohydride, and then passed through a Sephadex G-100 column.
Takagaki, Keiichi +3 more
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Neuroactive Chondroitin Sulfate Glycomimetics [PDF]
Journal of the American Chemical Society, 2008 We report the generation of chondroitin sulfate (CS) glycomimetics with tunable chemical and biological properties. Our approach greatly simplifies the synthesis of complex glycosaminoglycans, providing synthetically accessible, bioactive structures of programmable sulfation sequence.
Rawat, Manish +3 more
openaire +3 more sources
大腸菌を用いたフォスファカン（コンドロイチン硫酸プロテオグリカン）の融合コア蛋白の発現条件の検討 [PDF]
, 1996 Optimal conditions for expressing a specific region of core protein of phosphacan, a chondroitin sulfate proteoglycan known as receptor type protein tyrosine phosphatase, as fusion protein with glutathione S-transferase (GST) in E.coli were examined. DNA
Ito, Sekiko, Okamoto, Motoi
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