Results 11 to 20 of about 5,259 (265)
Ageing affects chondroitin sulfates and their synthetic enzymes in the intervertebral disc. [PDF]
Signal Transduct Target Ther, 2017 The depletion of chondroitin sulfates (CSs) within the intervertebral disc (IVD) during degenerative disc disease (DDD) results in a decrease in tissue hydration, a loss of fluid movement, cell apoptosis, a loss of nerve growth inhibition and ultimately,
Collin EC +8 more
europepmc +2 more sources
Chondroitin Sulfates Control Invasiveness of the Basal-Like Breast Cancer Cell Line MDA-MB-231 Through ROR1. [PDF]
Front Oncol, 2022 Extracellular and cell surface chondroitin sulfates (CSs) regulate cancer cell properties, including proliferation and invasion. Thus, it is necessary to understand the mechanisms underlying their roles in cancer.
Nadanaka S, Tamura JI, Kitagawa H.
europepmc +2 more sources
Influence of Propolis-Containing Nonwoven PLGA Dressings on Dermatan and Chondroitin Sulfate Dynamics During Burn-Wound Healing. [PDF]
Pharmaceuticals (Basel)Background/Objectives: Burn wounds are complex injuries associated with extensive inflammation, extracellular matrix (ECM) damage, and a high risk of impaired tissue remodeling and scarring.
Orlińska K +11 more
europepmc +2 more sources
Poultry Science, 2023 : This study aimed to assess the influence of glycosaminoglycan (chondroitin and glucosamine sulfates) supplementation in the diet of broilers on the expression of matrix metallopeptidase 9 (MMP-9) and metallopeptidase inhibitor 2 (TIMP-2) genes, the ...
Julyana M.S. Martins +8 more
doaj +1 more source
Regulatory Mechanisms in Biosystems, 2023 Osteodystrophy is caused by polyetiological factors, the main being disturbance of metabolism of macroelements and D and A vitamins. The disease continues to impose great economic losses on animal husbandry, reduces cattle productivity, and hinders ...
L. G. Slivinska +8 more
doaj +1 more source
Zaporožskij Medicinskij Žurnal, 2023 The aim of the study: to evaluate the course of metabolic processes after replacing femoral metaphysis defects with allogeneic bone implants saturated with allogeneic mesenchymal stem cells (MSCs) based on the analysis of serum biochemical indicators of ...
P. M. Vorontsov +3 more
doaj +1 more source
Dietary supplementation with glycosaminoglycans reduces locomotor problems in broiler chickens
Poultry Science, 2020 This study aimed to assess the influence of glycosaminoglycan (chondroitin and glucosamine sulfates) supplementation in the diet on the performance and incidence of locomotor problems in broiler chickens. A completely randomized design was carried out in
Julyana M.S. Martins +7 more
doaj +1 more source
Semi-synthesis of chondroitin sulfate-E from chondroitin sulfate-A [PDF]
Carbohydrate Polymers, 2012 Chondroitin sulfate-E (chondroitin-4, 6-disulfate) was prepared from chondroitin sulfate-A (chondroitin-4 - sulfate) by regioselective sulfonation, performed using trimethylamine sulfur trioxide in formamide under argon. The structure of semi-synthetic chondroitin sulfate-E was analyzed by PAGE, (1)H NMR, (13)C NMR, 2D NMR and disaccharide analysis and
Chao, Cai +6 more
openaire +2 more sources
Biphasic role of chondroitin sulfate in cardiac differentiation of embryonic stem cells through inhibition of Wnt/β-catenin signaling. [PDF]
PLoS ONE, 2014 The glycosaminoglycan chondroitin sulfate is a critical component of proteoglycans on the cell surface and in the extracellular matrix. As such, chondroitin sulfate side chains and the sulfation balance of chondroitin play important roles in the control ...
Robert D Prinz +3 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Oncofetal chondroitin sulfate expression plays an important role in the development of tumors and the pathogenesis of malaria in pregnancy. However, the biosynthesis and functions of these chondroitin sulfates, particularly the tissue-specific regulation
Zi-Yi Wu +10 more
doaj +1 more source