Results 281 to 290 of about 77,038 (354)

Assessment of the localization of chondroitin sulfate in various types of endometrial carcinoma. [PDF]

PLoS One
Hosokawa S, Norimatsu Y, Shinagawa A, Kurokawa T, Yoshida Y, Nishikawa T, Suzuki H, Irino S, Kobayashi TK.   +8 more
europepmc   +1 more source

The Glycocalyx: Barriers and Opportunities at Cell–Cell Encounters

Proteoglycan Research, Volume 3, Issue 4, October 2025.
ABSTRACT The glycocalyx, a carbohydrate‐rich, gel‐like layer that coats every mammalian cell, is the first point of contact between cells in tissues. It therefore critically influences these encounters, impacting their mechanical, electrical, and chemical features that ultimately determines the outcome of cell–cell contacts.
Lucas C. Wyss, Spencer A. Freeman
wiley   +1 more source

Chondroitin Sulfate Proteoglycan 4 (CSPG4) as an Emerging Target for Immunotherapy to Treat Melanoma. [PDF]

Cancers (Basel)
Chen X, Habib S, Alexandru M, Chauhan J, Evan T, Troka JM, Rahimi A, Esapa B, Tull TJ, Ng WZ, Fitzpatrick A, Wu Y, Geh JLC, Lloyd-Hughes H, Palhares LCGF, Adams R, Bax HJ, Whittaker S, Jacków-Malinowska J, Karagiannis SN.   +19 more
europepmc   +1 more source

Synthetic Biology and Biomaterials Strategies to Deceive the Tumor Microenvironment in CAR‐T Immunotherapy

Small, Volume 21, Issue 39, October 2, 2025.
A. Synthetic biology and biomaterials have emerged as tools to study and facilitate the treatment of solid tumors wi‐th chimeric antigen receptor‐CAR‐T cells. These strategies aim to resist the tumor microenvironment‐TME that presents cellular, biochemical, and mechanical immunosuppressive signals that hinder CAR‐T efficacy. B.
Grazia Marsico, Sudarshan GC, Velia Siciliano   +2 more
wiley   +1 more source

Chondroitin Sulfate-Based Nanocapsules as Nanocarriers for Drugs and Nutraceutical Supplements. [PDF]

Int J Mol Sci
Górniewicz M, Wnuk D, Foryś A, Trzebicka B, Michalik M, Kepczynski M.   +5 more
europepmc   +1 more source

Omics‐derived biological modules reflect tau positron emission tomography in Alzheimer's disease

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 11, Issue 4, October-December 2025.
Abstract BACKGROUND Tau neurofibrillary pathology is a hallmark of Alzheimer's disease (AD) and can be quantified in vivo using tau‐selective positron emission tomography (tau PET). Tau PET signal closely correlates with cognitive decline and disease stage, yet the molecular networks underpinning tau accumulation remain incompletely defined. METHODS We
Si‐Chun Gu, Qiao Yang Sun, Hui‐Qin Liu, Chang‐Yi Shen, Hang Su, Fang Xie, Qing Ye   +6 more
wiley   +1 more source

Macrophages producing chondroitin sulfate proteoglycan-4 induce neuro-cardiac junction impairment in Duchenne muscular dystrophy. [PDF]

J Pathol
Milan M, Maiullari F, Chirivì M, Ceraolo MG, Zigiotto R, Soluri A, Maiullari S, Landoni E, Silvestre DD, Brambilla F, Mauri P, De Paolis V, Fratini N, Crosti MC, Cordiglieri C, Parisi C, Calogero A, Seliktar D, Torrente Y, Lanzuolo C, Dotti G, Toccafondi M, Bombaci M, De Falco E, Bearzi C, Rizzi R.   +25 more
europepmc   +1 more source

Investigating the Effects of Epac2 Activation in an In Vitro Cortical Mechanical Injury Model for Central Nervous System Repair

European Journal of Neuroscience, Volume 62, Issue 8, October 2025.
Study design. An in vitro cortical mechanical injury model for central nervous system repair, which contained five major neural tissue cells, is established from rats. After 7 days in vitro, the injuries are introduced, and Epac2 agonist S‐220 treatments are applied immediately after injury.
Hongming Ma, Guy S. Bewick, Wenlong Huang   +2 more
wiley   +1 more source

Solid-Phase-Supported Chemoenzymatic Synthesis and Analysis of Chondroitin Sulfate Proteoglycan Glycopeptides. [PDF]

Angew Chem Int Ed Engl
Lin PH, Xu Y, Bali SK, Kim J, Gimeno A, Roberts ET, James D, Almeida NMS, Loganathan N, Fan F, Wilson AK, Jonathan Amster I, Moremen KW, Liu J, Jiménez-Barbero J, Huang X.   +15 more
europepmc   +1 more source