Results 71 to 80 of about 250,109 (264)
Advanced Science, EarlyView.Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang +10 more
wiley +1 more source
Effect of diclofenac sodium on the cartilage-regeneration potential of the chitosan-gelatin-chondroitin sulphate scaffold [PDF]
Iraqi Journal of Veterinary SciencesOsteoarthritis (OA) is a joint disorder that results in decreased chondrocyte function, leading to degradation of the extracellular matrix. Tissue engineering, mainly using scaffolds as implants at the affected joints, has emerged as an effective way to ...
Aniek S. Budiatin +5 more
doaj +1 more source
Advanced Science, EarlyView.CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li +13 more
wiley +1 more source
, 2005 Chondroitin sulfate A, chondroitin sulfate C, glucosamine hydrochloride and glucosamine sulfate are natural products that are becoming increasingly popular in the treatment of arthritis.
Foot, M, Mulholland, M
core +1 more source
Advanced Science, EarlyView.A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang +12 more
wiley +1 more source
Nanomaterials, 2016 The in situ formation of silver nanoparticles (AgNPs) aided by chondroitin sulfate and the preparation of a hierarchically structured silver-polymer nanocomposite with antimicrobial activity is shown.
María Jesús Hortigüela +3 more
doaj +1 more source
THE OCCURRENCE OF INTRACELLULAR CHONDROITIN SULFATE [PDF]
The Journal of Cell Biology, 1963 Suspensions of chondrocytes were prepared by treatment with trypsin of the epiphyses of tibias and femurs of 13-day-old chick embryos. After washing to remove the matrix, such suspensions readily incorporate radioactive sulfate into both intracellular and extracellular chondroitin sulfate.
F K, THORP, A, DORFMAN
openaire +2 more sources
NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment
Advanced Science, EarlyView.The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou +6 more
wiley +1 more source
Isotachophoretic determination of glucosamine and chondroitin sulphate in dietary supplements
Czech Journal of Food Sciences, 2013 Glucosamine and chondroitin sulfate, components of normal cartilage, are used as ingredients in dietary supplements intended to treat osteoarthritis and/or to support joint health.
Eliška VÁCLAVÍKOVÁ +1 more
doaj +1 more source
The effect of increasing the sulfation level of chondroitin sulfate on anticoagulant specific activity and activation of the kinin system. [PDF]
PLoS ONE, 2018 Oversulfated chondroitin sulfate (OSCS) was identified as a contaminant in certain heparin preparations as the cause of adverse reactions in patients. OSCS was found to possess both plasma anticoagulant activity and the ability to activate prekallikrein ...
J Hogwood +6 more
doaj +1 more source