Results 71 to 80 of about 265,373 (265)

Neonatal Sevoflurane Exposure Induces Long‐Term Cognitive Impairment via Epigenetically Mediated MMP9 Activation and Perineuronal Net Disruption in the Hippocampal CA2

open access: yesAdvanced Science, EarlyView.
Hippocampal CA2 perineuronal nets ensheathing excitatory pyramidal neurons are selectively vulnerable to repeated neonatal sevoflurane exposure. Epigenetic upregulation of MMP9 via reduced H3K27me3 disrupts PNN integrity, impairs BDNF–TrkB signaling, and causes synaptic protein loss and dendritic spine deficits, leading to persistent social and spatial
Lirong Liang   +11 more
wiley   +1 more source

Green Synthesis of Hierarchically Structured Silver-Polymer Nanocomposites with Antibacterial Activity

open access: yesNanomaterials, 2016
The in situ formation of silver nanoparticles (AgNPs) aided by chondroitin sulfate and the preparation of a hierarchically structured silver-polymer nanocomposite with antimicrobial activity is shown.
María Jesús Hortigüela   +3 more
doaj   +1 more source

THE OCCURRENCE OF INTRACELLULAR CHONDROITIN SULFATE [PDF]

open access: yesThe Journal of Cell Biology, 1963
Suspensions of chondrocytes were prepared by treatment with trypsin of the epiphyses of tibias and femurs of 13-day-old chick embryos. After washing to remove the matrix, such suspensions readily incorporate radioactive sulfate into both intracellular and extracellular chondroitin sulfate.
F K, THORP, A, DORFMAN
openaire   +2 more sources

Splenic Delivery System of pDNA through Complexes Electrostatically Constructed with Protamine and Chondroitin Sulfate [PDF]

open access: yes, 2018
We developed and optimized a novel gene delivery vector constructed electrostatically with an anionic biological component and a cationic biological component.
Hitoshi Sasaki   +19 more
core   +1 more source

Determination of Gene‐Level Fitness Contributions Across the Mucin‐Utilization Network of Bacteroides thetaiotaomicron

open access: yesAdvanced Science, EarlyView.
Genome‐wide CRISPRi and RNA‐seq resolve how B. thetaiotaomicron converts host mucosal glycans into fitness. The study reveals a layered mucin‐utilization architecture in which capsular polysaccharides constrain surface access, extracellular CAZymes and peptidases show functional redundancy, and intracellular catabolic pathways create discrete metabolic
Kangsan Kim   +5 more
wiley   +1 more source

Isotachophoretic determination of glucosamine and chondroitin sulphate in dietary supplements

open access: yesCzech Journal of Food Sciences, 2013
Glucosamine and chondroitin sulfate, components of normal cartilage, are used as ingredients in dietary supplements intended to treat osteoarthritis and/or to support joint health.
Eliška VÁCLAVÍKOVÁ   +1 more
doaj   +1 more source

The effect of increasing the sulfation level of chondroitin sulfate on anticoagulant specific activity and activation of the kinin system. [PDF]

open access: yesPLoS ONE, 2018
Oversulfated chondroitin sulfate (OSCS) was identified as a contaminant in certain heparin preparations as the cause of adverse reactions in patients. OSCS was found to possess both plasma anticoagulant activity and the ability to activate prekallikrein ...
J Hogwood   +6 more
doaj   +1 more source

Plasma syndecan-1, heparan sulfate and chondroitin sulfate concentrations during graft reperfusion.

open access: yes, 2019
Plasma syndecan-1, heparan sulfate and chondroitin sulfate concentrations during graft reperfusion.
Arie Passov (7251827)   +6 more
core   +1 more source

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

open access: yesAdvanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun   +12 more
wiley   +1 more source

INTRACELLULAR SYNTHESIS OF CHONDROITIN SULFATE [PDF]

open access: yesThe Journal of Cell Biology, 1962
In autoradiograms of slices of costal cartilage, incubated for 4 hours in a salt solution containing S35-sulfate and then washed extensively and dehydrated, about 85 per cent of the radioactivity was assignable to the chondrocytes. From alkaline extracts of similarly prepared slices of cartilage, 64 to 83 per cent of the total sulfur-35 in the slices ...
openaire   +2 more sources

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