Results 151 to 160 of about 43,424 (239)

Exosome‐Based Cartilage‐Targeted Delivery System: Strategies and Applications

open access: yesSmall Science, Volume 6, Issue 1, January 2026.
Construction strategies and applications of cartilage‐targeting exosomes. With the ageing of the global population, cartilage‐related diseases, such as osteoarthritis (OA) and intervertebral disc degeneration (IVDD), have increasingly become significant social problems threatening human health. Therefore, targeted therapy for cartilage is becoming more
Yao Wang   +3 more
wiley   +1 more source

Chondrocyte‐Targeted Nanoparticles Loaded with N‐Acetylcysteine Protect Articular Cartilage and Attenuate Osteoarthritis by Inhibiting Ferroptosis via Glutathione Maintenance

open access: yesSmall Science, Volume 6, Issue 1, January 2026.
Chondrocyte‐targeted CS‐NAC nanoparticles restore redox balance, inhibit ferroptosis, and protect cartilage under mechanical stress. This nanoplatform enhances joint retention, elevates GPX4 activity, and attenuates osteoarthritis progression, offering a promising disease‐modifying therapeutic strategy.
Shaoyi Wang   +8 more
wiley   +1 more source

Recent Advances in Orthopedic Tissue Engineering: Bridging Stem Cells and 3D Printing

open access: yesSmall Structures, Volume 7, Issue 1, January 2026.
This review highlights how diverse 3D‐printed scaffold platforms integrate with embryonic, mesenchymal, and induced pluripotent stem cells to guide musculoskeletal regeneration. By linking fabrication strategies with lineage‐specific cues and microenvironmental design principles, the article outlines emerging approaches that enable precise ...
Juyeong J. Lee   +3 more
wiley   +1 more source

Anti-chondroitin sulfate proteoglycan 4-specific antibodies modify the effects of vemurafenib on melanoma cells differentially in normoxia and hypoxia

open access: hybrid, 2015
Daniela Pucciarelli   +7 more
openalex   +2 more sources

Dual Growth Factor Release From Collagen Based Multilayer Films on Ti‐Surfaces Enhances Periimplant Bone Formation and Angiogenic Activity—An Experimental In‐Vivo Study

open access: yesClinical Oral Implants Research, Volume 37, Issue 1, Page 1-17, January 2026.
ABSTRACT Objectives The aim of the present study was to assess the effect of dual growth factor release from collagen‐based polyelectrolyte multilayer films (PEMs) on titanium implants on periimplant bone formation and angiogenetic activity in minipig mandibles.
Philipp Kauffmann   +7 more
wiley   +1 more source

Neural Organoids Protect Engineered Heart Tissues From Glucolipotoxicity by Transferring Versican in a Co‐Culture System

open access: yesCell Proliferation, Volume 59, Issue 1, January 2026.
In this study, Bai et al. established a co‐culture system between neural organoids (NOs) and engineered heart tissues (EHTs) and demonstrated that NOs could secrete versican, which was absorbed by EHTs to ameliorate glucolipotoxicity. ABSTRACT Metabolic disorders could cause dysregulated glucose and lipid at the systemic level, but how inter‐tissue ...
Baochen Bai   +22 more
wiley   +1 more source

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