Results 151 to 160 of about 43,424 (239)
Exosome‐Based Cartilage‐Targeted Delivery System: Strategies and Applications
Construction strategies and applications of cartilage‐targeting exosomes. With the ageing of the global population, cartilage‐related diseases, such as osteoarthritis (OA) and intervertebral disc degeneration (IVDD), have increasingly become significant social problems threatening human health. Therefore, targeted therapy for cartilage is becoming more
Yao Wang +3 more
wiley +1 more source
Chondrocyte‐targeted CS‐NAC nanoparticles restore redox balance, inhibit ferroptosis, and protect cartilage under mechanical stress. This nanoplatform enhances joint retention, elevates GPX4 activity, and attenuates osteoarthritis progression, offering a promising disease‐modifying therapeutic strategy.
Shaoyi Wang +8 more
wiley +1 more source
Augmented Chondroitin Sulfate Proteoglycan Has Therapeutic Potential for Intervertebral Disc Degeneration by Stimulating Anabolic Turnover in Bovine Nucleus Pulposus Cells under Changes in Hydrostatic Pressure. [PDF]
Takeoka Y +3 more
europepmc +1 more source
Recent Advances in Orthopedic Tissue Engineering: Bridging Stem Cells and 3D Printing
This review highlights how diverse 3D‐printed scaffold platforms integrate with embryonic, mesenchymal, and induced pluripotent stem cells to guide musculoskeletal regeneration. By linking fabrication strategies with lineage‐specific cues and microenvironmental design principles, the article outlines emerging approaches that enable precise ...
Juyeong J. Lee +3 more
wiley +1 more source
cDNA Cloning of the Basement Membrane Chondroitin Sulfate Proteoglycan Core Protein, Bamacan: A Five Domain Structure Including Coiled-Coil Motifs [PDF]
Rongrong Wu, John Couchman
openalex +1 more source
ABSTRACT Objectives The aim of the present study was to assess the effect of dual growth factor release from collagen‐based polyelectrolyte multilayer films (PEMs) on titanium implants on periimplant bone formation and angiogenetic activity in minipig mandibles.
Philipp Kauffmann +7 more
wiley +1 more source
In this study, Bai et al. established a co‐culture system between neural organoids (NOs) and engineered heart tissues (EHTs) and demonstrated that NOs could secrete versican, which was absorbed by EHTs to ameliorate glucolipotoxicity. ABSTRACT Metabolic disorders could cause dysregulated glucose and lipid at the systemic level, but how inter‐tissue ...
Baochen Bai +22 more
wiley +1 more source
Chondroitin sulfate proteoglycan 4 specific chimeric antigen receptor therapy for pediatric solid tumors [PDF]
Nicholas Tschernia +2 more
openalex +1 more source

