Results 61 to 70 of about 54,015 (281)
European Journal of Inflammation, 2003 Arthritis is estimated to affect over 30% of all adults and all the available drugs add considerable morbidity and mortality of their own. A recent therapeutic approach targets the mast cells that are currently considered critical in a variety of ...
T. C. Theoharides
doaj +1 more source
Journal of Neuroinflammation, 2012 Background Chondroitin sulfate proteoglycans are major inhibitory molecules for neural plasticity under both physiological and pathological conditions. The chondroitin sulfate degrading enzyme chondroitinase ABC promotes functional recovery after spinal ...
Tauchi Ryoji +8 more
doaj +1 more source
Immunotherapeutic Targeting of NG2/CSPG4 in Solid Organ Cancers
Vaccines, 2022 Neuro-glia antigen 2/chondroitin sulfate proteoglycan 4 (NG2/CSPG4, also called MCSP, HMW-MAA, MSK16, MCSPG, MEL-CSPG, or gp240) is a large cell-surface antigen and an unusual cell membrane integral glycoprotein frequently expressed on undifferentiated ...
Hongyu Zhang +6 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Chondroitin sulfate (CS), dermatan sulfate (DS) and heparan sulfate (HS) are covalently attached to specific core proteins to form proteoglycans in their biosynthetic pathways.
Shuji Mizumoto, Shuhei Yamada
doaj +1 more source
Auto-assemblies of Alpha-Cyclodextrin and Grafted Polysaccharides: Crystal Structure and Specific Properties of the Platelets [PDF]
, 2018 Cyclodextrins (CD) are a family of oligosaccharides with a toroid shape, which exhibit a remarkable ability to include guest molecules in their internal cavity providing a hydrophobic environment for poorly soluble molecules. Recently new types of inclusions of alpha CD with alkyl grafted polysaccharide chains (pullulan, chitosan, dextran, amylopectin,
arxiv +1 more source
A Large Chondroitin Sulfate Proteoglycan, Versican, in Porcine Predentin [PDF]
Journal of Oral Biosciences, 2011 Proteoglycans and their constituent glycosaminoglycan (GAG) have been proposed to be involved in the inhibition of mineralization in unmineralized tissue, predentin. Among the proteoglycans secreted by odontoblasts, we focused on the large chondroitin sulfate proteoglycan, versican, for its large binding capacity for calcium ions.
Makoto Fukae +3 more
openaire +3 more sources
Histopathologic and immunohistochemical features of capsular tissue around failed Ahmed glaucoma valves. [PDF]
PLoS ONE, 2017 Impervious encapsulation around Ahmed glaucoma valve (AGV) results in surgical failure raising intraocular pressure (IOP). Dysregulation of extracellular matrix (ECM) molecules and cellular factors might contribute to increased hydraulic resistance to ...
Alka Mahale +8 more
doaj +1 more source
Spatial and temporal changes in the distribution of proteoglycans during avian neural crest development [PDF]
, 1991 In this study, we describe the distribution of various classes of proteoglycans and their potential matrix ligand, hyaluronan, during neural crest development in the trunk region of the chicken embryo.
Bronner-Fraser, Marianne +5 more
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Management of Osteoarthritis with Avocado/Soybean Unsaponifiables. [PDF]
, 2015 Osteoarthritis (OA) is a painful and life-altering disease that severely limits the daily activity of millions of Americans, and is one of the most common causes of disability in the world. With obesity on the rise and the worlds population living longer,
Bhatti, Simi +3 more
core +1 more source
Chondroitin Sulfate Proteoglycans Are Associated with the Lesions of Alzheimer\u27s Disease [PDF]
, 1993 Chondroitin sulfate proteoglycans (CSPG) are extracellular matrix proteins inhibitory to neurite outgrowth in vitro and correlated with decreased neurite outgrowth after CNS injury.
Canning, David R. +3 more
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