Results 91 to 100 of about 10,804 (272)
What's New? Adoptive cell therapy (ACT) with tumor antigen‐specific CD8+ T cells has shown success in clinical trials treating patients with advanced or metastatic melanoma. Here, the authors established protocols for generating CD8+ T cells from human induced pluripotent stem cells (hiPSCs) expressing a melanoma‐specific T cell receptor (TCR) or ...
Juliane Poelchen+13 more
wiley +1 more source
The Chondroitin Sulfates of Healing Skin Wounds. [PDF]
John P. Bentley+2 more
openalex +1 more source
A dECM‐based cryogel scaffold with sustained VEGF release is developed to promote angiogenesis in ischemic tissues. Fabricated from decellularized porcine urinary bladder matrix and heparin, the scaffold supports VEGF binding and prolonged release. The cryogel demonstrates enhanced angiogenic potential in vitro and in a murine hindlimb ischemia model ...
Dayeon Roo+7 more
wiley +1 more source
Recent Advances in Injectable Hydrogel Biotherapeutics for Regenerative Dental Medicine
This review analyses multifunctional injectable hydrogels, natural or synthetic, physically or chemically crosslinked, that deliver exosomes, stem cells, and other bioactive cues to inflamed or damaged oral tissues. We discuss their immunomodulatory, antimicrobial, angiogenic, and osteogenic capacities, highlighting advances that enable regenerative ...
Renan Dal‐Fabbro+6 more
wiley +1 more source
Low-molecular-weight chondroitin sulfate was obtained by degradation of chondroitin sulfate using hyaluronidase. Then, separated with sephadex G25, DEAE-52, and finally purified with AKATA superpeptide separation system and fluorescence-assisted ...
Jinpeng Wang, Lian Zhang, Zhengyu Jin
doaj
Protein glycosylation in lung cancer from a mass spectrometry perspective
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi+2 more
wiley +1 more source
Microfluidic Synthesis of Collagen‐Based Microgels for Tissue Engineering Applications
We present a droplet microfluidic approach for preparing porous and irregularly shaped microgels of fibrillar collagen and collagen‐glycosaminoglycan (GAG) copolymer in a continuous oil phase at rates of up to 5500 s−1. ABSTRACT To expand the use of collagen‐based biomaterials beyond their current applications in three‐dimensional (3D) cell culture ...
Ehsan Samiei+2 more
wiley +1 more source
Upcycling Eggshell Matrix for Sustainable Production of Glycosaminoglycans. [PDF]
An Overview of Glycosaminoglycans Recovery Techniques and Their Diverse Applications. ABSTRACT Glycosaminoglycans (GAGs) are biomolecules with applications in the pharmaceutical, cosmetic, and nutraceutical industries. However, traditional GAG sources, such as animal tissues and marine organisms, present imminent challenges, including structural ...
Cobbinah-Sam E, Ekaette I.
europepmc +2 more sources
Interstitial Cystitis/Bladder Pain Syndrome in Men
ABSTRACT Aims In April 2025, the Wake Forest Institute for Regenerative Medicine hosted a Global Consensus meeting on interstitial cystitis/bladder pain syndrome (IC/BPS) in Winston‐Salem, NC. The goal of this meeting was to establish attainable targets in phenotyping, diagnosis, and biomarkers for IC/BPS.
Madeline Snipes+5 more
wiley +1 more source
Biochemical Findings in Normal and Osteoarthritic Articular Cartilage. II. Chondroitin Sulfate Concentration and Chain Length, Water, and Ash Content* [PDF]
Alfred Jay Bollet, Joanne L. Nance
openalex +1 more source