Results 91 to 100 of about 10,804 (272)

Generation and functional analysis of melanoma antigen‐specific CD8+ T cells derived from S/MAR vector‐transfected human induced pluripotent stem cells

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Adoptive cell therapy (ACT) with tumor antigen‐specific CD8+ T cells has shown success in clinical trials treating patients with advanced or metastatic melanoma. Here, the authors established protocols for generating CD8+ T cells from human induced pluripotent stem cells (hiPSCs) expressing a melanoma‐specific T cell receptor (TCR) or ...
Juliane Poelchen   +13 more
wiley   +1 more source

The Chondroitin Sulfates of Healing Skin Wounds. [PDF]

open access: bronze, 1965
John P. Bentley   +2 more
openalex   +1 more source

Development of a Decellularized Urinary Bladder Matrix and Heparin‐Based Cryogel for Promoting Angiogenesis

open access: yesMacromolecular Bioscience, EarlyView.
A dECM‐based cryogel scaffold with sustained VEGF release is developed to promote angiogenesis in ischemic tissues. Fabricated from decellularized porcine urinary bladder matrix and heparin, the scaffold supports VEGF binding and prolonged release. The cryogel demonstrates enhanced angiogenic potential in vitro and in a murine hindlimb ischemia model ...
Dayeon Roo   +7 more
wiley   +1 more source

Recent Advances in Injectable Hydrogel Biotherapeutics for Regenerative Dental Medicine

open access: yesMacromolecular Bioscience, EarlyView.
This review analyses multifunctional injectable hydrogels, natural or synthetic, physically or chemically crosslinked, that deliver exosomes, stem cells, and other bioactive cues to inflamed or damaged oral tissues. We discuss their immunomodulatory, antimicrobial, angiogenic, and osteogenic capacities, highlighting advances that enable regenerative ...
Renan Dal‐Fabbro   +6 more
wiley   +1 more source

Separation and purification of low-molecular-weight chondroitin sulfates and their anti-oxidant properties

open access: yesBangladesh Journal of Pharmacology, 2016
Low-molecular-weight chondroitin sulfate was obtained by degradation of chondroitin sulfate using hyaluronidase. Then, separated with sephadex G25, DEAE-52, and finally purified with AKATA superpeptide separation system and fluorescence-assisted ...
Jinpeng Wang, Lian Zhang, Zhengyu Jin
doaj  

Protein glycosylation in lung cancer from a mass spectrometry perspective

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi   +2 more
wiley   +1 more source

Microfluidic Synthesis of Collagen‐Based Microgels for Tissue Engineering Applications

open access: yesNano Select, EarlyView.
We present a droplet microfluidic approach for preparing porous and irregularly shaped microgels of fibrillar collagen and collagen‐glycosaminoglycan (GAG) copolymer in a continuous oil phase at rates of up to 5500 s−1. ABSTRACT To expand the use of collagen‐based biomaterials beyond their current applications in three‐dimensional (3D) cell culture ...
Ehsan Samiei   +2 more
wiley   +1 more source

Upcycling Eggshell Matrix for Sustainable Production of Glycosaminoglycans. [PDF]

open access: yesBiopolymers
An Overview of Glycosaminoglycans Recovery Techniques and Their Diverse Applications. ABSTRACT Glycosaminoglycans (GAGs) are biomolecules with applications in the pharmaceutical, cosmetic, and nutraceutical industries. However, traditional GAG sources, such as animal tissues and marine organisms, present imminent challenges, including structural ...
Cobbinah-Sam E, Ekaette I.
europepmc   +2 more sources

Interstitial Cystitis/Bladder Pain Syndrome in Men

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Aims In April 2025, the Wake Forest Institute for Regenerative Medicine hosted a Global Consensus meeting on interstitial cystitis/bladder pain syndrome (IC/BPS) in Winston‐Salem, NC. The goal of this meeting was to establish attainable targets in phenotyping, diagnosis, and biomarkers for IC/BPS.
Madeline Snipes   +5 more
wiley   +1 more source

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