Results 71 to 80 of about 8,176 (252)

Chemoenzymatic preparation of Chondroitin sulfates with a defined sulfation pattern [PDF]

, 2016
Comunicación Oral impartida en el XVII European Congress on ...
Bastida, Agatha, Doncel-Pérez, Ernesto, Fernández-Mayoralas, Alfonso, García-Junceda, Eduardo, Garrido, Leoncio, Montero-Calle, Pilar, Moreno-Zafra, Víctor, Revuelta, Julia   +7 more
core   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Antigenicity of Chondroitin Sulfate.

Experimental Biology and Medicine, 1957
SummaryChondroitin sulfate extracted from human costal cartilage was prepared in 3 different ways for inoculation into rabbits, (1) a 1% solution, (2) a 1% solution incubated with heat-killed, group A, type 3, hemolytic streptococcus, and (3) a 1% solution incubated with heat-killed Staphylococcus aureus. These 3 preparations were injected into rabbits
R W, QUINN, R, CERRONI
openaire   +2 more sources

Tunable 3D‐Printed Static Mixers for Gradient Bioprinting With High Cell Viability

Advanced Materials Technologies, EarlyView.
ABSTRACT The fabrication of native tissue‐like structures with gradual transitions in material properties, cell types, and growth factors remains a major challenge in biofabrication due to the lack of suitable methods. Mimicking the hierarchical organization of living tissues is essential for functional models, yet creating gradient, multimaterial ...
Florian Hofmann, Jessica Faber, Franz Moser, Alessandro Cianciosi, Nicoletta Murenu, Joachim Schenk, Katrin G. Heinze, Natascha Schaefer, Silvia Budday, Tomasz Jungst   +9 more
wiley   +1 more source

The endothelial glycocalyx: composition, functions, and visualization [PDF]

, 2007
This review aims at presenting state-of-the-art knowledge on the composition and functions of the endothelial glycocalyx. The endothelial glycocalyx is a network of membrane-bound proteoglycans and glycoproteins, covering the endothelium luminally.
Sietze Reitsma, Dick W. Slaaf, Hans Vink, Marc A. M. J. van Zandvoort, Mirjam G. A. oude Egbrink, P Algenstaedt, S Ali, BL Allen, ML Ballinger, AL Barker, A Beresewicz, MC Berndt, RJ Beuk, L Bode, L Bode, T Bombeli, DJ Carey, AA Constantinescu, FR Curry, S Das, PF Davies, C Desjardins, CF Dewey Jr, VS Dole, XL Du, MG Egbrink, JD Esko, SP Evanko, JA Florian, LA Fransson, JR Fromm, JL Funderburgh, L Ghitescu, RM Gibson, M Gouverneur, N Grammatikakis, DN Granger, YF Han, GK Hansson, CB Henry, CB Henry, C Hjalmarsson, G Ho, AJ Hoogewerf, X Hu, MT Huang, VH Huxley, NS Ihrcke, RV Iozzo, M Jacob, GH Janssen, U Jung, GS Kansas, H Kato, MG Kinsella, B Klitzman, B Klitzman, JA Koedam, H Kresse, AM Kupinski, I Kurose, TC Laurent, JY Lee, Q Li, P Libby, X Lin, HH Lipowsky, HH Lipowsky, F Lopez-Casillas, JA Lopez, JH Luft, RTA Megens, CC Michel, S Mochizuki, AW Mulivor, AM Muller, A Nandi, DM Nathan, M Nieuwdorp, M Nieuwdorp, M Nieuwdorp, MG Oliver, MG oude Egbrink, JR Pappenheimer, KA Parker, KD Patel, N Perrimon, AR Pries, AR Pries, AR Pries, AR Pries, NS Quinsey, R Raman, A Rapraeger, A Rapraeger, M Rehm, CJ Robinson, R Ross, J Rostgaard, J Rostgaard, GM Rubanyi, I Rubio-Gayosso, C Ruegg, ZM Ruggeri, S Salek-Ardakani, IH Sarelius, K Sasaki, JE Scott, JE Scott, JB Seal, TW Secomb, K Shimada, M Sperandio, M Sperandio, D Spillmann, TA Springer, EH Starling, RJ Stewart, K Sugahara, L Tan, JM Tarbell, JM Tarbell, LM Title, E Tkachenko, AM Tovar, A Ueda, B Berg van den, BM Berg van den, BM Berg van den, PM Haaren van, PM Haaren van, M Zandvoort van, H Vink, H Vink, H Vink, CA Vogl-Willis, B Vollmar, CS Wang, BJ Ward, PH Weigel, H Weiler, S Weinbaum, S Weinbaum, W Weninger, LC Wilsie, G Wu, JP Xiong, K Yamashita, X Zhang, L Zhuo   +149 more
core   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Targeting nanoparticles to lung cancer-derived A549 cells based on changes on interstitial stiffness in biomimetic models

iScience
Summary: The mechanical properties and forces of the extracellular environment modulate alveolar epithelial cell behavior. To model cancer/fibrosis associated stiffening and dynamic stretch, a biomimetic device was developed that imitates the active ...
Afia Ibnat Kohon, Kun Man, Ala Hessami, Katelyn Mathis, Jade Webb, Joanna Fang, Parsa Radfar, Yong Yang, Brian Meckes   +8 more
doaj   +1 more source

Fucose-Rich Sulfated Polysaccharides from Two Vietnamese Sea Cucumbers Bohadschia argus and Holothuria (Theelothuria) spinifera: Structures and Anticoagulant Activity

Marine Drugs, 2022
Fucosylated chondroitin sulfates (FCSs) FCS-BA and FCS-HS, as well as fucan sulfates (FSs) FS-BA-AT and FS-HS-AT were isolated from the sea cucumbers Bohadschia argus and Holothuria (Theelothuria) spinifera, respectively.
Nadezhda E. Ustyuzhanina, Maria I. Bilan, Andrey S. Dmitrenok, Eugenia A. Tsvetkova, Sofya P. Nikogosova, Cao Thi Thuy Hang, Pham Duc Thinh, Dinh Thanh Trung, Tran Thi Thanh Van, Alexander S. Shashkov, Anatolii I. Usov, Nikolay E. Nifantiev   +11 more
doaj   +1 more source

Hyaluronan concentration and size distribution in human knee synovial fluid: variations with age and cartilage degeneration. [PDF]

, 2016
BackgroundOne potential mechanism for early superficial cartilage wear in normal joints is alteration of the lubricant content and quality of synovial fluid.
Chen, Albert C, D'Lima, Darryl D, Hansen, Bradley C, Hasegawa, Akihiko, Koziol, Jim, Lotz, Martin K, Masuda, Koichi, Quach, Phu, Ren, Shuwen, Sah, Robert L, Temple-Wong, Michele M   +10 more
core   +1 more source

BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer‐Associated Fibroblasts Crosstalk

Advanced Science, EarlyView.
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi, Ming‐yang Wu, Jin‐quan Liu, Cuicui Tian, Li Ma, Xue‐mei Zhou, Ze‐Hao Sun, Zhi‐yong Xu, Run‐dong Zhang, Shan‐yuan Ye, Li‐ming Huang, Yan Wang, Jing‐shu Xiong, Wen‐bo Bu, Xian‐feng Cheng, Jian‐fang Sun, Hao Chen   +16 more
wiley   +1 more source