Results 181 to 190 of about 7,722 (218)
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Antioxidant Activity of Chondroitin Sulfate
2006Publisher Summary Molecules in biological systems often perform more than one function. Many structures have the ability to scavenge free radicals, acting in living organisms as antioxidants, although their main biological function is different. During oxidative stress, the increase in the concentration of these molecules seems to be a biological ...
Adriana Ferlazzo +4 more
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Microbial production and metabolic engineering of chondroitin and chondroitin sulfate
Emerging Topics in Life Sciences, 2018Several commercial uses and potential novel applications have recently been described for chondroitin sulfate (CS). However, the currently applied animal extractive procedure has a high environmental impact, which may become more profound especially in relation to the forecasted expansion of the CS market for applications as a food supplement ...
Cimini D., Restaino O. F., Schiraldi C.
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In Vitro Effects of Chondroitin Sulfate
2006Publisher Summary A number of in vitro studies have been performed to determine the mode of action of chondroitin sulfate (CS). It has been demonstrated that CS possesses both anabolic effects on cartilage metabolism and anticatabolic properties. In various models of cartilage culture or of isolated chondrocytes, CS has demonstrated the capacity to ...
A. Fioravanti, G. Collodel
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Isolation and Purification of Chondroitin Sulfate
2006Publisher Summary This chapter discusses methods for the isolation and purification of chondroitin sulfate (CS). This molecule is a sulfated glycosaminoglycan (GAG) composed of a linear polysaccharide chain with repeating disaccharides of defined structures that usually contain one hexosamine, one hexuronic acid, and a sulfate ester.
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[34] Microsomal sulfation of proteochondroitin, chondroitin, and chondroitin oligosaccharides
1989Publisher Summary This chapter focuses on the microsomal sulfation of proteochondroitin, chondroitin, and chondroitin oligosaccharides. Chondroitin sulfate—a polymer of gIucuronic acid (GlcA) and N-acetyl galactosamine (GalNAc)—can be sulfated on either or both the 4 and 6 positions of the GalNAc and on the 2 position of the GlcA. Chondroitin sulfate
Donald E. Humphries +2 more
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Chondroitin Sulfate and RBC Clumping
Archives of Ophthalmology, 1984To the Editor. —Chondroitin sulfate is a new viscoelastic substance that is advocated as a protective agent for intraocular lens insertion. Chondroitin sulfate has been shown to be more effective in protecting the endothelium of animal and human corneas than other substances.1Contact of intraocular lenses with endothelium causes endothelial damage and
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Immunology of Chondroitin/Dermatan Sulfate
1995Variable substitutions and locations of the sulfate esters along the backbone of chondroitin/dermatan sulfate chains, combined with their carbohydrate structures, present topographies to immune systems which can be recognized as antigenic. This has led to the development of a number of monoclonal antibodies which recognize distinct epitopes in the ...
Ronald J. Midura +3 more
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Chondroitin Sulfate Proteoglycans in Tumor Progression
2006Publisher Summary This chapter discusses the implication of stromal and cell surface chondroitin sulfate proteoglycans (CSPGs) to the different aspects of tumor growth and metastasis. In a developing tumor, several CSPGs are overexpressed and deposited into extracellular matrix (ECM) during the stromal reaction. The accumulated PGs participate in the
Wegrowski, Y., F.X., Maquart
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Chondroitin sulfate for knee osteoarthritis
Annals of the Rheumatic Diseases, 2018The apparent efficacy of chondroitin sulfate in treating knee osteoarthritis reported by Reginster et al 1 must be considered in the context of the literature on this subject. The results of trials of chondroitin and/or glucosamine for relief of pain caused by osteoarthritis of the knee and hip have been …
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Degradation of Chondroitin Sulfate and Dermatan Sulfate with Chondroitin Lyases
2003Robert J. Linhardt, María J. Hernáiz
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