Results 161 to 170 of about 5,259 (265)

Expression of chondroitin sulfotransferases in the injured spinal cord

, 2004
We demonstrated that chondroitinase ABC infused into the graft-host interface resolved the glial scar and improved prospects of axonal regeneration into the distal host spinal cord.
Chau, CH, Liu, J, Shum, DKY, Chan, YS
core  

Mechanisms of Pericyte‐Mediated Cancer Metastasis

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Pericytes play multifarious roles in promoting cancer metastasis by facilitating metastatic cancer cell dissemination, circulating tumor cell survival, tissue extravasation, premetastatic niche formation, and metastatic tumor growth. These cells have intertwined interactions with vascular endothelial cells to modulate cancer cell behavior and ...
Ziheng Guo, Yihai Cao
wiley   +1 more source

Formation and Characterization of Insoluble Anthocyanins‐λ‐carrageenan Biopolyelectrolyte Complexes: Structural Morphology, Thermal Stability, and Release Dynamics

ChemFoodChem, Volume 2, Issue 2, June 2026.
Insoluble biopolyelectrolyte complexes formed between blackberry anthocyanins and λ‐carrageenan are investigated. Optimal complexation occurs at low carrageenan ratios and acidic pH, producing porous hydrogel‐like structures with enhanced thermal stability.
Tomás Garrido, Ana Rita Pereira, Hiléia K. S. Souza, Nuno Mateus, Victor de Freitas, Ana Fernandes   +5 more
wiley   +1 more source

Nanoshell Fabrication Techniques for Probiotic Encapsulation: A Comprehensive Review

eFood, Volume 7, Issue 3, June 2026.
ABSTRACT Probiotics, beneficial microorganisms, confer numerous health benefits when administered. However, their efficacy is hindered by harsh gut conditions, including acidity, bile acids, and enzymatic degradation. To overcome these challenges, encapsulation and nanoshell technology have emerged as a pivotal strategy to enhance probiotic stability ...
Tuba Mustafa, Muhammad Afzaal, Farhan Saeed, Amna Shahbaz, Zainab Hira, Ayesha Adil, Tayyaba Sohail, Faiyaz Ahmed, Maryam Amanullah, Hina Sarwar, Noor Akram, Saad Mansoor, Gebremichael Gebremedhin Hailu   +12 more
wiley   +1 more source

The Substrate Specificity of Testicular Hyaluronidase and Its Use in Sequencing Chondroitin Sulfates

, 1982
Testicular hyaluronidase was used to study the distribution of sulfated disaccharide units along chondroitin sulfate chains. The transglycosylation activity of the hyaluronidase was eliminated by use of excess levels of a second enzyme, (beta ...
Knudson, Warren
core  

RXR Gamma Enables Oligodendrocyte Differentiation by Suppressing Sonic Hedgehog Signaling

Glia, Volume 74, Issue 6, June 2026.
Using pharmacogenetic approaches, Baldassarro et al. demonstrate that RXRγ suppresses the SHH signaling pathway in OPCs to ensure their efficient differentiation following T3 stimulation. Accordingly, Rxrg−/− OPCs displayed compromised differentiation which was normalized by the pharmacological inhibition of the hyperactive SHH pathway.
Vito Antonio Baldassarro, Quentin Brassart, Valérie Fraulob, Laura Calzà, Wojciech Krezel   +4 more
wiley   +1 more source

Ceragenin‐Loaded Tri‐Layered Skin Substitute Composed of Natural and Synthetic Biopolymers for Burn Wound Healing

Journal of Biomedical Materials Research Part A, Volume 114, Issue 6, June 2026.
ABSTRACT Burn wounds present significant clinical challenges due to high infection risk, delayed healing, and extensive tissue damage. The development of biomimetic skin substitutes capable of simultaneously supporting tissue regeneration and preventing infection remains a critical need in burn wound management. In this study, a novel ceragenin (CSA‐44)
Nawal Aljayyousi, Emel Tamahkar Irmak, Esra Karaca, Elif Tümay Özer, Oğuzhan Akgün, Ferda Arı, Aycan Yiğit Çınar, Çağla Bozkurt Güzel, Paul B. Savage, Bilgen Osman   +9 more
wiley   +1 more source

Glycosaminoglycans and vitamin C in ovo and the feeding of broiler chickens influence bone and cartilaginous histology

Ciência Animal Brasileira
The objective of this study is to evaluate the effect of in ovo feeding and dietary supplementation with glycosaminoglycans (GAGs) and vitamin C, on the bone and cartilage histology of broiler chickens.
Arthur Zuanetti Curti, Elaine Talita Santos, Lizandra Amoroso, Julyana Machado da Silva Martins, Jean Kaique Valentim, Sarah Sgavioli   +5 more
doaj  

Reciprocal Macrophage‐MSC Crosstalk Drives Immunomodulatory and Regenerative Phenotypes in a Mineralized Collagen Scaffold

Journal of Biomedical Materials Research Part A, Volume 114, Issue 6, June 2026.
Macrophage‐MSC interactions are dynamic. Following injury, neutral (M0) macrophages arrive at the defect site and polarize towards M1 (pro‐inflammatory) macrophages, which can secrete inflammatory and cell recruitment factors. MSCs in this inflammatory defect can take on a licensed state in which they secrete a series of immunomodulatory factors that ...
Vasiliki Kolliopoulos, Maxwell Polanek, Hashni E. Vidana Gamage, Melisande Wong Yan Ling, Aleczandria Tiffany, Erik R. Nelson, Kara L. Spiller, Brendan A. C. Harley   +7 more
wiley   +1 more source

Viscoelastic and Morphologic Changes in the Lumbar Intervertebral Discs of the 5xFAD Mouse Model of Alzheimer's Disease

JOR SPINE, Volume 9, Issue 2, June 2026.
The intervertebral discs (IVDs) from mice with amyloid pathologies are larger, flatter, and exhibit increased energy absorption, making these IVDs more susceptible to damage. This heightened vulnerability may predispose elderly individuals with AD to disc injuries, accelerating IVD degeneration and spinal pain. ABSTRACT Background Chronic low back pain,
C. E. Gonzalez, C. A. Schurman, K. A. Wilson, B. Schilling, L. M. Ellerby, S. Y. Tang   +5 more
wiley   +1 more source