Results 81 to 90 of about 7,722 (218)

Fucosylated and Sulfated Glycans Investigated using Cryogenic Infrared Spectroscopy [PDF]

open access: yes, 2022
Unusual monosaccharides (fucose), covalent modifications of glycans (sulfation) and terminal sequences play important biological roles in physiology and pathology of living organisms.
Lettow, M.
core  

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

open access: yesSmall Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles(LNPs)and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu   +6 more
wiley   +1 more source

The Biomaterial and Blood Clot Complex: A Crucial Early Environment for Osteo‐Coagulo‐Immunomodulation and the Advancement of Bone Biomaterials

open access: yesSmall Structures, EarlyView.
Various properties of bone biomaterials can modulate components of the blood clot (including the fibrin network, red blood cells, platelets, and the complement system) in vivo implantation, leading to the formation of a biomaterial–blood clot complex (BBCC) significantly impacting subsequent osteoimmunomodulation.
Zongpu Han   +11 more
wiley   +1 more source

Graft detachment rates in surgeon‐cut and pre‐cut tissue for DSAEK transported in different mediums

open access: yesActa Ophthalmologica, Volume 103, Issue 3, Page 281-288, May 2025.
Abstract Purpose To analyse graft detachment rates after Descemet stripping automated endothelial keratoplasty (DSAEK) using surgeon‐cut grafts and pre‐cut grafts transported in different mediums. Methods A retrospective study of graft detachment rates including 265 surgeries (240 patients) performed between 2019 and 2023.
Thorbjörg Olafsdottir   +4 more
wiley   +1 more source

Investigating the Role of Aggrecan in Intervertebral Disc Degeneration [PDF]

open access: yes, 2018
Low back pain affects nearly 85% of the population of the United States, and is associated with a huge socioeconomic burden. One of the leading causes of low back pain is Intervertebral Disc (IVD) degeneration, which results in an ingrowth of blood ...
King, Brian
core  

Role of IL‐34 in Tumors and Its Application to Regulate Inflammation

open access: yesCancer Science, Volume 116, Issue 5, Page 1164-1170, May 2025.
IL‐34 and its receptors. ABSTRACT Interleukin (IL)‐34 is a relatively recently discovered cytokine which binds to colony‐stimulating factor‐1 receptor (CSF‐1R). So far, there has been no clear explanation as to why CSF‐1R requires two ligands. While CSF‐1 is ubiquitously expressed, the expression of IL‐34 is relatively restricted.
Yuichi Igarashi, Ken‐ichiro Seino
wiley   +1 more source

Cataract Surgery in the Small Adult Eye: A Review

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Modern cataract surgery continues to advance, yet intraocular lens (IOL) based surgery in the small adult eye remains challenging. Thorough preoperative assessment and surgical preparation optimise postoperative outcomes in these cases. Advances in IOL power calculation, including artificial intelligence‐driven formulas, improve accuracy ...
Jonathan E. Moore   +2 more
wiley   +1 more source

Engineering Intervertebral Disc Regeneration: Biomaterials, Cell Sources and Animal Models

open access: yesCell Proliferation, EarlyView.
This review highlights the current tissue engineering approaches utilising biomaterials, animal models and cell sources for intervertebral disc regeneration and discusses future opportunities. ABSTRACT Intervertebral disc (IVD) degeneration is an age‐related problem triggering chronic spinal issues, such as low back pain and IVD herniation.
Sidong Yang   +8 more
wiley   +1 more source

Measuring intraventricular pressure in developing mouse embryos: Uncovering a repetitive mechanical cue for brain development

open access: yesDevelopment, Growth &Differentiation, EarlyView.
We developed a high‐time resolution system using a piezoresistive sensor to measure brain intraventricular pressure in mouse embryos (E12.5 to E16.5). Ex utero measurements revealed a constant baseline pressure, whereas in utero measurements uncovered striking periodic pressure fluctuations synchronized with uterine contractions.
Mami Akaike   +3 more
wiley   +1 more source

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