Evidence of Mitochondrial Dysfunction in Bacterial Chondronecrosis With Osteomyelitis–Affected Broilers [PDF]
A leading cause of lameness in modern broilers is bacterial chondronecrosis with osteomyelitis (BCO). While it is known that the components of BCO are bacterial infection, necrosis, and inflammation, the mechanism behind BCO etiology is not yet fully ...
Alison Ferver +3 more
doaj +4 more sources
Role of autophagy machinery dysregulation in bacterial chondronecrosis with osteomyelitis
: Autophagy is a cell survival and homeostasis mechanism involving lysosomal degradation of cellular components and foreign bodies. It plays a role in bone homeostasis, skeletal diseases, and bacterial infections as both a cell-survival or cell-death ...
Alison Ramser +4 more
doaj +4 more sources
Radiologic Findings of Cricoid Chondronecrosis after Intubation in the Setting of COVID-19. [PDF]
This case series examines seven patients diagnosed with cricoid chondronecrosis after intubation in the setting of COVID‐19 and presents a novel “cricoid chondronecrosis computed tomography (CT) grading rubric” to standardize reporting of radiological findings.
Hassman B, Cayci Z, Misono S, Gray R.
europepmc +4 more sources
Cricoid chondronecrosis: A serious complication of prolonged endotracheal intubation – Case report
Introduction and importance: Chondronecrosis is a rare life-threatening complication of endotracheal intubation. Only few cases have been reported in the literature. Here, we present a case report and discuss the diagnosis of the condition, the causative
Mohammed Laachoubi +5 more
doaj +2 more sources
Assessing the Impact of Spraying an E. faecium Probiotic at Hatch and Supplementing Feed with a Triple-Strain Bacillus-Based Additive on BCO Lameness Incidence in Broiler Chickens [PDF]
Bacterial chondronecrosis with osteomyelitis (BCO) is a major cause of lameness in broiler chickens. This condition arises when bacteria from the gastrointestinal or aerosol tract migrate to infect bone microfractures, often exacerbated by rapid growth ...
Khawla Alharbi +6 more
doaj +2 more sources
Assessing the Impact of Spraying an Enterococcus faecium-Based Probiotic on Day-Old Broiler Chicks at Hatch on the Incidence of Bacterial Chondronecrosis with Osteomyelitis Lameness Using a Staphylococcus Challenge Model [PDF]
Bacterial chondronecrosis with osteomyelitis (BCO) lameness is a bone disease characterized by the translocation of bacteria from the gastrointestinal tract, which colonize microfractures in broiler leg bones caused by rapid animal growth rate and weight
Anh Dang Trieu Do +5 more
doaj +2 more sources
Evaluating the Effectiveness of Probiotic and Multivalent Vaccination Strategies in Mitigating Bacterial Chondronecrosis with Osteomyelitis Lameness Using a Hybrid Challenge Model [PDF]
Bacterial chondronecrosis with osteomyelitis (BCO) is caused by several bacteria, including Salmonella, Staphylococcus spp., Escherichia coli, Enterococcus spp., and Mycoplasma spp., and BCO is a significant animal health and welfare issue in broiler ...
Amanda Anthney +9 more
doaj +2 more sources
Preliminary Investigation of Cecal Microbiota in Experimental Broilers Reared Under the Aerosol Transmission Lameness Induction Model [PDF]
Bacterial chondronecrosis with osteomyelitis (BCO), and its associated lameness, is one of the most common and devastating issues the poultry industry constantly faces, both globally and domestically.
Anh Dang Trieu Do +4 more
doaj +2 more sources
Local and Systemic Cytokine, Chemokine, and FGF Profile in Bacterial Chondronecrosis with Osteomyelitis (BCO)-Affected Broilers [PDF]
Complex disease states, like bacterial chondronecrosis with osteomyelitis (BCO), not only result in physiological symptoms, such as lameness, but also a complex systemic reaction involving immune and growth factor responses.
Alison Ramser +3 more
doaj +4 more sources
RNA-seq reveals downregulated osteochondral genes potentially related to tibia bacterial chondronecrosis with osteomyelitis in broilers [PDF]
Background Bacterial chondronecrosis with osteomyelitis (BCO) develops in the growth plate (GP) of the proximal femur and tibia and is initiated by damage to the less mineralized chondrocytes followed by colonization of opportunistic bacteria.
Haniel Cedraz de Oliveira +6 more
doaj +3 more sources

