Results 121 to 130 of about 56,482 (307)
Abstract Objective To summarize the outcomes of 1000 consecutive microsurgical resection of cerebellopontine angle tumors. Study Design Retrospective cohort study. Setting Single tertiary care institution. Methods We analyzed 1000 patients who underwent microsurgical resection of cerebellopontine angle tumors between November 2017 and August 2024 ...
Joshua Lee +9 more
wiley +1 more source
Description of the immune microenvironment of chondrosarcoma and contribution to progression
Chondrosarcoma (CHS) is a rare bone malignancy characterized by its resistance to conventional systemic and radiation therapies. Whether immunotherapy targeting immune checkpoints may be active in these tumors remains unknown.
François A. Simard +7 more
doaj +1 more source
Background As major regulators of normal chondrogenesis, the bone morphogenic protein (BMP) and transforming growth factor β (TGFB) signaling pathways may be involved in the development and progression of central chondrosarcoma. In order to uncover their
Boeuf Stephane +6 more
doaj +1 more source
BackgroundConventional chondrosarcomas are malignant cartilage tumors considered radioresistant. Nevertheless, retrospective series show a small but significant survival benefit for patients with locally advanced disease treated with radiotherapy.
Y. de Jong +9 more
semanticscholar +1 more source
Optimum imaging for sinonasal malignancy [PDF]
A combination of computed tomography (CT) and magnetic resonance imaging (MRI) is now established as the optimum assessment of sinonasal malignancy.
Howard, D, Lloyd, G, Lund, VJ, Savy, L
core +1 more source
Abstract Indocyanine green (ICG) is a well‐established near‐infrared dye which has been used clinically for several decades. Recently, it has been utilised for fluorescence‐guided surgery in a range of solid cancer types, including sarcoma, with the aim of reducing the positive margin rate.
Corey David Chan +8 more
wiley +1 more source
Survival and prognostic factors in conventional central chondrosarcoma
Chondrosarcoma is the second most frequent primary malignant bone tumor. Treatment is mainly based on surgery. In general, wide resection is advocated at least in G2 and G3 tumors. But which margins should be achieved? Does localization as for example in
Julian Fromm +8 more
semanticscholar +1 more source
Abstract Background Only 30%–40% of high‐grade sarcomas respond to initial chemotherapy, which can have significant toxicities. Computed tomography imaging alone has limitations in evaluating treatment response. Imaging with 5‐fluoro‐deoxyglucose–positron emission tomography/computed tomography (FDG‐PET/CT), which evaluates tumor metabolism, offers an ...
Edward Y. Cheng +10 more
wiley +1 more source
Chondrosarcoma is a primary malignant bone cancer, with a potent capacity to invade locally and cause distant metastasis; it has a poor prognosis and shows a predilection for metastasis to the lungs.
Chih-Yang Lin +6 more
doaj +1 more source
Unlike other malignant bone tumors including osteosarcomas and Ewing sarcomas with a peak incidence in adolescents and young adults, conventional and dedifferentiated chondrosarcomas mainly affect people in the 4th to 7th decade of life.
K. Boehme +3 more
semanticscholar +1 more source

