Results 121 to 130 of about 56,482 (307)

Microsurgical Outcomes in 1000 Patients With Cerebellopontine Angle Tumors: A Comprehensive Cohort Analysis

open access: yesOtolaryngology–Head and Neck Surgery, Volume 173, Issue 5, Page 1236-1244, November 2025.
Abstract Objective To summarize the outcomes of 1000 consecutive microsurgical resection of cerebellopontine angle tumors. Study Design Retrospective cohort study. Setting Single tertiary care institution. Methods We analyzed 1000 patients who underwent microsurgical resection of cerebellopontine angle tumors between November 2017 and August 2024 ...
Joshua Lee   +9 more
wiley   +1 more source

Description of the immune microenvironment of chondrosarcoma and contribution to progression

open access: yesOncoImmunology, 2017
Chondrosarcoma (CHS) is a rare bone malignancy characterized by its resistance to conventional systemic and radiation therapies. Whether immunotherapy targeting immune checkpoints may be active in these tumors remains unknown.
François A. Simard   +7 more
doaj   +1 more source

BMP and TGFbeta pathways in human central chondrosarcoma: enhanced endoglin and Smad 1 signaling in high grade tumors

open access: yesBMC Cancer, 2012
Background As major regulators of normal chondrogenesis, the bone morphogenic protein (BMP) and transforming growth factor β (TGFB) signaling pathways may be involved in the development and progression of central chondrosarcoma. In order to uncover their
Boeuf Stephane   +6 more
doaj   +1 more source

Radiotherapy resistance in chondrosarcoma cells; a possible correlation with alterations in cell cycle related genes

open access: yesClinical Sarcoma Research, 2019
BackgroundConventional chondrosarcomas are malignant cartilage tumors considered radioresistant. Nevertheless, retrospective series show a small but significant survival benefit for patients with locally advanced disease treated with radiotherapy.
Y. de Jong   +9 more
semanticscholar   +1 more source

Optimum imaging for sinonasal malignancy [PDF]

open access: yes, 2002
A combination of computed tomography (CT) and magnetic resonance imaging (MRI) is now established as the optimum assessment of sinonasal malignancy.
Howard, D, Lloyd, G, Lund, VJ, Savy, L
core   +1 more source

Investigating the mechanisms of indocyanine green tumour uptake in sarcoma cell lines and ex vivo human tissue

open access: yesThe Journal of Pathology, Volume 267, Issue 3, Page 315-328, November 2025.
Abstract Indocyanine green (ICG) is a well‐established near‐infrared dye which has been used clinically for several decades. Recently, it has been utilised for fluorescence‐guided surgery in a range of solid cancer types, including sarcoma, with the aim of reducing the positive margin rate.
Corey David Chan   +8 more
wiley   +1 more source

Survival and prognostic factors in conventional central chondrosarcoma

open access: yesBMC Cancer, 2018
Chondrosarcoma is the second most frequent primary malignant bone tumor. Treatment is mainly based on surgery. In general, wide resection is advocated at least in G2 and G3 tumors. But which margins should be achieved? Does localization as for example in
Julian Fromm   +8 more
semanticscholar   +1 more source

5‐fluoro‐deoxyglucose PET/CT response after neoadjuvant chemotherapy predicts long‐term outcomes in soft tissue sarcomas: Results from a prospective trial

open access: yesCancer, Volume 131, Issue 20, 15 October 2025.
Abstract Background Only 30%–40% of high‐grade sarcomas respond to initial chemotherapy, which can have significant toxicities. Computed tomography imaging alone has limitations in evaluating treatment response. Imaging with 5‐fluoro‐deoxyglucose–positron emission tomography/computed tomography (FDG‐PET/CT), which evaluates tumor metabolism, offers an ...
Edward Y. Cheng   +10 more
wiley   +1 more source

β5 integrin up-regulation in brain-derived neurotrophic factor promotes cell motility in human chondrosarcoma.

open access: yesPLoS ONE, 2013
Chondrosarcoma is a primary malignant bone cancer, with a potent capacity to invade locally and cause distant metastasis; it has a poor prognosis and shows a predilection for metastasis to the lungs.
Chih-Yang Lin   +6 more
doaj   +1 more source

Chondrosarcoma: A Rare Misfortune in Aging Human Cartilage? The Role of Stem and Progenitor Cells in Proliferation, Malignant Degeneration and Therapeutic Resistance

open access: yesInternational Journal of Molecular Sciences, 2018
Unlike other malignant bone tumors including osteosarcomas and Ewing sarcomas with a peak incidence in adolescents and young adults, conventional and dedifferentiated chondrosarcomas mainly affect people in the 4th to 7th decade of life.
K. Boehme   +3 more
semanticscholar   +1 more source

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