Results 61 to 70 of about 587,547 (217)

Asymmetric Evolution of Antennal Cell Types Underlies a Derived Ammonia‐Sensing Logic for Ecological Adaptation in Bactrocera dorsalis

Advanced Science, EarlyView.
Comparative antennal single‐nucleus transcriptomics reveals cell‐type‐dependent transcriptomic divergence in Bactrocera dorsalis, with similar structural cells but divergent sensory neurons. This neuronal diversification is associated with a distinct ammonia‐sensing pathway, linking female attraction to bird‐dropping‐associated cues with nutritional ...
Wei Liu, Shuai Zhang, Jie Zhang, Zhen Tian, Yuanbo Xue, Ling Yang, Jun Xu, Guirong Wang   +7 more
wiley   +1 more source

A new method for computing the vertex PI index with applications to special classes of graphs

AKCE International Journal of Graphs and Combinatorics
The Padmakar-Ivan (PI) index of a graph G is given by [Formula: see text], where [Formula: see text] is the number of equidistant vertices for the edge e.
S. C. Manju, K. Somasundaram, Yilun Shang   +2 more
doaj   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

CDK4/MERCs/PINK1 Axis Drives PFOA/HFPO‐TA‐Induced Cardiac Senescence via Mitophagy Defect and cGAS‐STING Activation: In Vitro Amelioration by Cycloastragenol

Advanced Science, EarlyView.
The present study demonstrated that PFOA and HFPO‐TA exposure suppressed CDK4, disrupted MERCs and impaired PINK1/Parkin‐mediated mitophagy, thereby accelerating cardiac senescence, whereas CAG effectively reversed these pathological changes in vitro. Our findings identify CDK4 as a critical regulator bridging mitophagy defects and cardiac senescence ...
Nuo‐Wa Li, Jun‐Ze Jiang, Ying‐Ying Liu, Tian‐Tian Zhang, Kanwar Kumar Malhi, Xin Yao, Jin‐Long Li   +6 more
wiley   +1 more source

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

Advanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan, Lixin Tian, Lianjie Peng, Jingyu Zhang, Lining Lin, Xiaoting Zhang, Yaxian Luo, Zhichao Liu, Xinhua Yao, Mouyuan Sun, Yong He, Mengfei Yu, Huiming Wang   +12 more
wiley   +1 more source

The Topological Connectivity of the Independence Complex of Circular-Arc Graphs

Universal Journal of Mathematics and Applications, 2019
Let us denoted the topological connectivity of a simplicial complex $C$ plus 2 by $\eta(C)$. Let $\psi$ be a function from class of graphs to the set of positive integers together with $\infty$. Suppose $\psi$ satisfies the following properties: \newline
Yousef Abd Algani
doaj   +1 more source

Graph searching on chordal graphs

, 2012
[[abstract]]Two variations of the graph searching problem, edge searching and node searching, are studied on several classes of chordal graphs, which include split graphs, interval graphs and k-starlike graphs[[fileno]]2030209030014[[department ...
Peng, Sheng-Lung;Ko, Ming-Tat;Ho, Chin-Wen;Hsu, Tsan-sheng;Tang, Chuan-Yi
core   +1 more source

Dualizing chordal graphs [PDF]

, 2003
Although chordal graphs may seem at first to be a poor choice to approach using cycle/cutset graph duality, portions of chordal graph theory can be successfully dualized within the context of nonseparable 3-edge-connected graphs.
McKee, Terry A.
core   +1 more source

Symbiont‐Induced HSP83 Establishes Two‐Tiered Control of Antifungal Immunity in an Invasive Beetle–Fungus Complex

Advanced Science, EarlyView.
In an invasive beetle–fungus complex, the mutualist Leptographium procerum induces host HSP83 and modulates Toll‐dependent antifungal immunity. HSP83 mediates two‐tiered control by associating with selected fungal recognition receptors and restraining Dorsal‐driven antimicrobial peptide transcription.
Qingtai Yang, Zhudong Liu, Yuqiao Yin, Jing Su, Dunyang Yu, Longsheng Xing, Zhen Zou, Le Kang, Jianghua Sun   +8 more
wiley   +1 more source

Minimal Elimination Ordering Inside a Given Chordal Graph [PDF]

, 1997
We consider the following problem, called Relative Minimal Elimination Ordering. Given a graph G=(V,E) which is a subgraph of the chordal graph G'=(V,E'), compute an inclusion minimal chordal graph G''=(V,E''), such that E subseteq E'' subseteq E'.
Dahlhaus, Elias
core   +1 more source