Single-institution clinical experience using robust intensity modulated proton therapy in chordoma and chondrosarcoma of the mobile spine and sacrum: Feasibility and need for plan adaptation [PDF]
, 2021 Michiel Kroesen +12 more
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The Journal of Pathology: Clinical Research, Volume 11, Issue 6, November 2025.Abstract Bone and soft tissue sarcomas are a diagnostic challenge due to their histological complexity, variety, and mutational heterogeneity. This has led to continued refinements in classification and diagnostic criteria, presented and soon to be updated by the WHO.
William CH Cross
wiley +1 more source
Sacrectomía en bloque para tumores gigantes del sacro preservando las raíces de S1. Reporte de nueva técnica quirúrgica y resultado funcional [PDF]
, 2017 Los tumores primarios de sacro son lesiones raras que se caracterizan por ser localmente agresivos, de naturaleza osteolítica y con gran potencial para recurrir a corto plazo.
Buritica, J.L +3 more
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Imaging Findings of a Nonenhancing Intradural Paramedian Chordoma Mimicking an Epidermoid Cyst
대한영상의학회지, 2018 Intracranial chordoma is a rare tumor, originating from embryonic remnants of the primitive notochord. It typically appears as an enhancing extradural midline tumor with bone involvement.
Min Jeong Kim, Yae Won Park, Soo Mee Lim
doaj +1 more source
Monitoring of hadrontherapy treatments by means of charged particle detection [PDF]
, 2016 The interaction of the incoming beam radiation with the patient body in hadrontherapy treatments produces secondary charged and neutral particles, whose detection can be used for monitoring purposes and to perform an on-line check of beam particle ...
Battistoni, Giuseppe +22 more
core +1 more source
Spinal Cord, 1987 Intraspinal chordomas are rare tumors, comprising about 1% of central nervous system tumors. They are derived from notochordal elements which have failed to degenerate and are mainly found in the sphenooccipital and sacrococcygeal regions. These tumors are very slowly growing, are virtually impossible to excise completely and only metastasise in about ...
openaire +2 more sources
RAB3B Dictates mTORC1/S6 Signaling in Chordoma and Predicts Response to mTORC1‐Targeted Therapy
Advanced ScienceChordoma, a rare mesenchymal malignancy, exhibits a high tendency to postoperative recurrence and poor prognosis. To date, its tumorigenic regulatory mechanisms remain elusive, leading to a lack of effective therapeutic targets and drug sensitivity ...
Jianxuan Gao +15 more
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A zebrafish model of chordoma initiated by notochord-driven expression of HRASV12
Disease Models & Mechanisms, 2014 Chordoma is a malignant tumor thought to arise from remnants of the embryonic notochord, with its origin in the bones of the axial skeleton. Surgical resection is the standard treatment, usually in combination with radiation therapy, but neither ...
Alexa Burger +7 more
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Rare case of neglected large sacral Chordoma in a young female treated by wide En bloc resection and Sacrectomy [PDF]
, 2018 Zi Hao Phang +4 more
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Journal of the Belgian Society of Radiology, 2013 A 38-year-old man was admitted to our hospital for deep sacral pain. There was no significant medical history. Physical examination revealed pressure pain of the right sacroiliac joint. MRI showed a midline mass in the sacrum (arrows), isointense on T1- weighted MR images and hyperintense on T2-weighted MR images (Fig.
Behaeghe, M +3 more
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