Results 51 to 60 of about 17,061 (210)

Detection of microbial cell-free DNA in maternal and umbilical cord plasma in patients with chorioamnionitis using next generation sequencing.

PLoS ONE, 2020
BACKGROUND:Chorioamnionitis has been linked to spontaneous preterm labor and complications such as neonatal sepsis. We hypothesized that microbial cell-free (cf) DNA would be detectable in maternal plasma in patients with chorioamnionitis and could be ...
Russell G Witt, Lily Blair, Michela Frascoli, Michael J Rosen, Quoc-Hung Nguyen, Sivan Bercovici, Simona Zompi, Roberto Romero, Tippi C Mackenzie   +8 more
doaj   +1 more source

Postpartum febrile morbidity following vacuum‐assisted birth: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate whether vacuum‐assisted birth (VAB) independently increases the risk of postpartum febrile morbidity, identifying a potentially modifiable contributor to maternal infectious morbidity. Methods This retrospective cohort study was conducted at a university‐affiliated tertiary maternity center between 2011 and 2023.
Itamar Gilboa, Daniel Gabbai, Lee Reicher, Emmanuel Attali, Yariv Yogev, Anat Lavie   +5 more
wiley   +1 more source

Day-to-day dynamics of fetal heart rate variability to detect chorioamnionitis in preterm premature rupture of membranes.

PLoS ONE
BackgroundChorioamnionitis is recognized as a major consequence of preterm premature rupture of membranes (PPROM), and a frequent cause of neonatal morbidity and mortality.
Aline Taoum, Guy Carrault, Caroline Tesson, Maxime Esvan, Bruno Laviolle, Linda Lassel   +5 more
doaj   +1 more source

Maternal and infant gut microbiome

iMeta, EarlyView.
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang, Felicia Tin, Hui Chen, Fuxin Jiao, Min Wu, Shanshan Sun, Lisha Lin, Die Li, Huimin Zheng, Zhenxin Niu, Mengyao Lan, Bahtiyar Yilmaz, Johan G. Eriksson, Mengjia Wang, Andrew Macpherson, Jose C. Clemente, Jia Xu, Ri‐hua Xie, Xiaojiao Zheng, Tao Zhou, Jinfeng Wang, Wei Shen, Bing Huang, Xia Chen, Hai Li, Yan He   +25 more
wiley   +1 more source

Reinterpreting potential biomarker in umbilical cord as a marker of chorioamnionitis and funisitis in prelabor ROM

Majalah Obstetri dan Ginekologi
HIGHLIGHTS • HsCRP and IL-6 levels in umbilical cord blood serve as reliable early biomarkers of chorioamnionitis and funisitis in prelabor ROM, enabling more accurate neonatal sepsis risk assessment and targeted clinical intervention.
Julian Dewantiningrum, Besari Adi Pramono, Agoes Oerip Poerwoko, Budi Irawan, Rizky Aditya Bachrudin, Herman Kristanto   +5 more
doaj   +1 more source

sFlt‐1/PlGF Ratio in the Diagnosis of Preeclampsia on the MAGLUMI X3 Analyzer

Journal of Clinical Laboratory Analysis, EarlyView.
We compared the analytical and clinical performance of MAGLUMI X3 (Snibe) and Elecsys (Roche) for measuring sFlt‐1, PlGF, and their ratio in women hospitalized at the Department of Gynecology and Obstetrics, University Hospital in Pilsen. In a single‐center, real‐world cohort (192 samples from 164 patients), method comparison showed good agreement ...
Pavel Broz, Simona Kukralova, Zdenek Sebesta, Katerina Brslicova, Michal Kozerovsky, Jaroslav Racek, Daniel Rajdl   +6 more
wiley   +1 more source

Clinic‐Based Transnasal Marsupialization for the Treatment of Congenital Dacryocystocele

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate the feasibility and outcomes of endoscopic intranasal marsupialization as treatment for congenital dacryocystocele, performed under topical anesthesia in a clinical setting. Study Design A retrospective review was conducted at a tertiary pediatric care hospital spanning from 2014 to 2024.
Camille Caron, Charlotte Lussier, Annie Lapointe, Rosanne Superstein, Erika Mercier   +4 more
wiley   +1 more source

Hemolytic Disease of the Fetus and Newborn: Fetal RHD Genotyping, Targeted Prophylaxis, and Prenatal Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemolytic disease of the fetus and newborn (HDFN) remains a significant concern in prenatal care primarily caused by maternal alloimmunization against fetal red blood cell antigens, most commonly the D antigen. Noninvasive fetal RHD genotyping, used as a screening tool, enables targeted antenatal prophylaxis and has been implemented in several
Emilie Thorup, Steffen Thorsen, Morten Hanefeld Dziegiel, Olav Bjørn Petersen, Frederik Banch Clausen   +4 more
wiley   +1 more source

Intrauterine Transfusions in Fetuses Affected by Parvovirus B19: Complications, Challenges and Outcomes

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This study evaluates the procedural characteristics, complications, and outcomes of intrauterine transfusion (IUT) for fetal anemia caused by parvovirus B19 infection during the 2023–2024 epidemic in Northwestern Europe. Method This multicenter observational study included all fetuses undergoing IUT for proven parvovirus B19‐induced ...
Banu Özbakir, Emma Van den Eede, Lone N. Nørgaard, Roland Devlieger, Karin Sundberg, Monique C. Haak, Femke Slaghekke   +6 more
wiley   +1 more source

Human Umbilical Cord Mesenchymal Stem Cell‐Derived Microvesicles Alleviate Bronchopulmonary Dysplasia in Preterm Rats by Inhibiting Neutrophil Extracellular Trap Formation

Pediatric Discovery, EarlyView.
Excessive neutrophil extracellular trap (NET) extrusion (NETosis) links prenatal inflammation to bronchopulmonary dysplasia (BPD) pathogenesis. Treatment with human umbilical cord mesenchymal stem cell‐derived microvesicles suppresses NET formation, reduces lung injury, and promotes alveolarization in a preterm rat model, offering a promising cell‐free
Yi Lu, Wen Tan, Xiao Yang, Tingting Luo, Chenghao Mei, Huaqin Bu, Jinhua Ma, Chao Gong, Li Zhong, Ou Zhou, Daiyin Tian   +10 more
wiley   +1 more source