Funisitis Predicts Poor Respiratory Outcomes in Extremely Preterm Neonates [PDF]
Background/Objectives: Histological chorioamnionitis (HCAM) is a risk factor of chronic lung disease (CLD) in preterm neonates. Funisitis, an indicator of fetal inflammatory response, has been linked to adverse neonatal outcomes, but its impact on ...
Yi-Li Hung +2 more
doaj +4 more sources
A Public Health Scourge: The Recent Surge of an Ancient Disease. [PDF]
The recent resurgence of congenital syphilis is striking, with an increase in cases 10‐fold over the past 12 years, including a 30% rise within the past 3 years alone. The consequences of untreated maternal syphilis can be severe, contributing to significant fetal and neonatal illness and death in cases of congenital syphilis.
Pleiss A, Kuntz M, Strauch S, Roe S.
europepmc +2 more sources
Chorioamnionitis in the Second Trimester Secondary to Multidrug-Resistant <i>Haemophilus influenzae</i> Infection. [PDF]
Purpose Nontypeable Haemophilus influenzae (NTHi) is an emerging perinatal pathogen linked to chorioamnionitis, preterm birth, and early pregnancy loss. This case report describes the presentation, microbiologic findings, and management of second‐trimester NTHi‐associated chorioamnionitis, emphasizing diagnostic challenges and antimicrobial ...
Carlson KS, Korthals MB.
europepmc +2 more sources
Frozen Section of Placental Membranes and Umbilical Cord: A Valid Diagnostic Tool for Early-Onset Neonatal Sepsis Management [PDF]
Early-onset neonatal sepsis (EONS), a serious infection in newborns within 3 days, is challenging to diagnose. The current methods often lack accuracy, leading to unnecessary antibiotics or delayed treatment.
Veronica Parrella +9 more
doaj +2 more sources
The association of chorioamnionitis with intraventricular hemorrhage and long-term outcome in very preterm neonates [PDF]
ObjectiveTo evaluate the impact of chorioamnionitis on the incidence of intraventricular hemorrhage in preterm neonates and to assess its impact on neurodevelopmental outcomes at 24 months of age.MethodsWe retrospectively reviewed the medical records of ...
Eftychia Drogouti +7 more
doaj +2 more sources
Gestational Age-Dependent Effects of Antenatal Magnesium Sulfate on Fetal S100B Levels: An Observational Study Using Cord Serum. [PDF]
ABSTRACT Aim Magnesium sulfate (MgSO4) is widely used for fetal neuroprotection in preterm births before 32 weeks of gestation, yet it remains unclear whether its effect depends on gestational age. S100 calcium‐binding protein B (S100B), a protein secreted by astrocytes, is recognized as a biomarker of neural distress.
Shimaya T +7 more
europepmc +2 more sources
Calcified necrotizing funisitis and its association with adverse neonatal outcomes: a case-control study [PDF]
Background Necrotizing funisitis (NF) is a rare but severe type of umbilical inflammation. Whether NF can affect the outcomes of newborns is still controversal.
Lei Peng +5 more
doaj +2 more sources
Stillbirth in Iceland 1996-2021: Incidence and etiology. [PDF]
Over the study period, the stillbirth rate decreased due to reduction in preterm stillbirth, with fewer cases attributed to infection and placental abruption. Cord complications and placental insufficiency were the commonest causes, both increasing with gestational age. More stillbirths were attributed to placental insufficiency, reflecting the lack of
Bjarnadottir RI +6 more
europepmc +2 more sources
ADAR1 could be a potential diagnostic target for intrauterine infection patients [PDF]
Intrauterine infection (IUI) is mainly an ascending infection in which vaginal and cervical pathogens ascend to the uterus and can affect the fetus. Until now, there is still no effective diagnostic biomarker for IUI, such as chorioamnionitis (CAM) and ...
Keiichiro Nakamura +5 more
doaj +2 more sources
Diagnostic tests for the prediction of histological chorioamnionitis and funisitis in pregnant women with preterm premature rupture of membranes: A systematic review. [PDF]
Background Infection of the amniotic cavity is an important driver and/or consequence of preterm prelabour rupture of membranes (PPROM). Prediction of infection is challenging, limiting guidance for interventions during the antenatal period. Infection typically triggers a host inflammatory response, and non‐invasive indirect markers of the maternal or ...
Lanzarone V +3 more
europepmc +2 more sources

