ADAR1 could be a potential diagnostic target for intrauterine infection patients [PDF]
Intrauterine infection (IUI) is mainly an ascending infection in which vaginal and cervical pathogens ascend to the uterus and can affect the fetus. Until now, there is still no effective diagnostic biomarker for IUI, such as chorioamnionitis (CAM) and ...
Keiichiro Nakamura +5 more
doaj +2 more sources
Case Report: A neonatal case of cryopyrin-associated periodic syndrome with severe funisitis and neonatal asphyxia [PDF]
Cryopyrin-associated periodic syndrome (CAPS) is a genetic disorder and autoinflammatory disease characterized by chronic inflammation throughout the body.
Yuri Hayashida +7 more
doaj +2 more sources
Objetivo: Evaluar la utilidad del Doppler de la arteria umbilical (AU) para predecir invasión microbiana de la cavidad amniótica (IMCA), funisitis y resultado adverso neonatal (RA) en pacientes con rotura prematura de membranas de pretérmino (RPMPT ...
Alfredo Ovalle S. +7 more
doaj +2 more sources
A Public Health Scourge: The Recent Surge of an Ancient Disease. [PDF]
The recent resurgence of congenital syphilis is striking, with an increase in cases 10‐fold over the past 12 years, including a 30% rise within the past 3 years alone. The consequences of untreated maternal syphilis can be severe, contributing to significant fetal and neonatal illness and death in cases of congenital syphilis.
Pleiss A, Kuntz M, Strauch S, Roe S.
europepmc +2 more sources
Two cases of Leukemoid reaction in premature infants caused by fetal inflammatory response syndrome [PDF]
Background Fetal inflammatory response syndrome (FIRS) is a systemic inflammatory response caused by the activation of the fetal immune system. The serological diagnostic criterion for fetal inflammatory response syndrome is a cord blood interleukin-6 ...
Meng-Ting Feng +3 more
doaj +2 more sources
Chorioamnionitis in the Second Trimester Secondary to Multidrug-Resistant <i>Haemophilus influenzae</i> Infection. [PDF]
Purpose Nontypeable Haemophilus influenzae (NTHi) is an emerging perinatal pathogen linked to chorioamnionitis, preterm birth, and early pregnancy loss. This case report describes the presentation, microbiologic findings, and management of second‐trimester NTHi‐associated chorioamnionitis, emphasizing diagnostic challenges and antimicrobial ...
Carlson KS, Korthals MB.
europepmc +2 more sources
Background Intrauterine inflammation affects short- and long-term neonatal outcomes. Histological chorioamnionitis and funisitis are acute inflammatory responses in the fetal membranes and umbilical cord, respectively.
Hyo Kyozuka +9 more
doaj +1 more source
Gestational Age-Dependent Effects of Antenatal Magnesium Sulfate on Fetal S100B Levels: An Observational Study Using Cord Serum. [PDF]
ABSTRACT Aim Magnesium sulfate (MgSO4) is widely used for fetal neuroprotection in preterm births before 32 weeks of gestation, yet it remains unclear whether its effect depends on gestational age. S100 calcium‐binding protein B (S100B), a protein secreted by astrocytes, is recognized as a biomarker of neural distress.
Shimaya T +7 more
europepmc +2 more sources
Subsequent pregnancy outcomes according to the presence of acute histologic chorioamnionitis in women with spontaneous preterm delivery [PDF]
ObjectiveTo compare subsequent pregnancy outcomes according to the presence of acute histologic chorioamnionitis (HCA) in women with spontaneous preterm delivery (SPTD).MethodsAmong 1,706 women who gave birth twice or more at our institution, 138 women ...
Nam-Kyeong Kim +5 more
doaj +1 more source

