Results 41 to 50 of about 1,820 (193)

RNA Sequencing Reveals Diverse Functions of Amniotic Fluid Neutrophils and Monocytes/Macrophages in Intra-Amniotic Infection

Journal of Innate Immunity, 2020
Intra-amniotic infection, the invasion of microbes into the amniotic cavity resulting in inflammation, is a clinical condition that can lead to adverse pregnancy outcomes for the mother and fetus as well as severe long-term neonatal morbidities.
Nardhy Gomez-Lopez, Roberto Romero, Aneesha Varrey, Yaozhu Leng, Derek Miller, Bogdan Done, Yi Xu, Gaurav Bhatti, Kenichiro Motomura, Meyer Gershater, Roger Pique-Regi, Adi L. Tarca   +11 more
doaj   +1 more source

Placental Lesions in Meconium Aspiration Syndrome [PDF]

Journal of Pathology and Translational Medicine, 2017
Background Meconium aspiration syndrome (MAS) is defined by respiratory distress requiring supplemental oxygen in a meconium-stained neonate. MAS is clinically subclassified as mild, moderate, and severe according to the oxygen requirement.
Binnari Kim, Soo-young Oh, Jung-Sun Kim
doaj   +1 more source

Diagnostic tests for the prediction of histological chorioamnionitis and funisitis in pregnant women with preterm premature rupture of membranes: A systematic review. [PDF]

Aust N Z J Obstet Gynaecol
Background Infection of the amniotic cavity is an important driver and/or consequence of preterm prelabour rupture of membranes (PPROM). Prediction of infection is challenging, limiting guidance for interventions during the antenatal period. Infection typically triggers a host inflammatory response, and non‐invasive indirect markers of the maternal or ...
Lanzarone V, Polkinghorne A, Eslick G, Branley J.   +3 more
europepmc   +2 more sources

Association of Chorioamnionitis with Aberrant Neonatal Gut Colonization and Adverse Clinical Outcomes. [PDF]

PLoS ONE, 2016
Chorioamnionitis (inflammation of the placenta and fetal membranes) and abnormal gastrointestinal colonization have been associated with an increased risk of sepsis and death in preterm infants, but whether chorioamnionitis causes abnormal pioneering ...
Kriti Puri, Diana H Taft, Namasivayam Ambalavanan, Kurt R Schibler, Ardythe L Morrow, Suhas G Kallapur   +5 more
doaj   +1 more source

Placental histopathology in late preterm infants: clinical implications [PDF]

Clinical and Experimental Pediatrics, 2020
Background The etiopathogenesis of late preterm (LPT) birth is undetermined. Placental histopathology, which reflects an adverse intrauterine environment and is reportedly associated with preterm labor and neonatal morbidities, has not been studied in ...
Kristina Ericksen, Joshua Fogel, Rita P. Verma   +2 more
doaj   +1 more source

Clinical chorioamnionitis at term VI: acute chorioamnionitis and funisitis according to the presence or absence of microorganisms and inflammation in the amniotic cavity [PDF]

, 2015
Artículo de publicación ISIObjective: Neonates born to mothers with clinical chorioamnionitis at term are at an increased risk of infection. Acute subchorionitis, chorioamnionitis, and funisitis are considered placental histologic features consistent ...
Kusanovic, Juan Pedro, Nikolina Docheva, Jacques, Suzanne M., Docheva, Nikolina, Kim, Yeon Mee, Hassan, Sonia S., Romero, Roberto, Chaiworapongsa, Tinnakorn, Qureshi, Faisal, Bo Hyun Yoon, Roberto Romero, Juan P. Kusanovic, Yeo, Lami, Faisal Qureshi, Ahmed, Ahmed I., Korzeniewski, Steven J., Chong Jai Kim, Chaiyasit, Noppadol, Jung-Sun Kim, Chaemsaithong, Piya, Yoon, Bo Hyun, Kim, Chong Jai, Piya Chaemsaithong, Sonia S. Hassan, Kim, Jung-Sun, Tinnakorn Chaiworapongsa, Steven J. Korzeniewski, Lami Yeo, Suzanne M. Jacques, Yeon Mee Kim, Ahmed I. Ahmed, Noppadol Chaiyasit   +31 more
core   +1 more source

Funisitis is associated with adverse neonatal outcome in low-risk unselected deliveries at or near term [PDF]

, 2015
This study aimed to determine the incidence and clinical outcomes for varying patterns of placental histological inflammation (consistent with fetal or maternal inflammatory response) in an unselected population of >1000 women with a singleton pregnancy ...
Sebire, NJ, Hook, CE, N. J. Sebire, F. A. Jessop, C. C. Lees, Pathak, S, C. E. Hook, Lees, CC, S. Pathak, Jessop, FA   +9 more
core   +1 more source

Funisitis and raised interleukin 6 concentrations in gastric aspirates at birth [PDF]

Archives of Disease in Childhood - Fetal and Neonatal Edition, 2005
From the second trimester to near term, fetuses in utero can swallow up to 500–1000 ml amniotic fluid a day, which assists in normal development of the gastrointestinal system.1,2 The aims of this study were to determine whether the concentration of gastric interleukin 6 (IL6) immediately after birth was associated with funisitis, the histological ...
Y D, Kim, W Y, Hyun, H J, Cha
openaire   +2 more sources

Evidence of both foetal inflammation and hypoxia–ischaemia is associated with meconium aspiration syndrome

Scientific Reports, 2021
Foetal hypoxia–ischaemia is a key trigger of meconium aspiration syndrome (MAS). However, many neonates develop MAS without evidence of hypoxia–ischaemia, suggesting the presence of covert but important risk variables. We evaluated the association of MAS
Kyoko Yokoi, Osuke Iwata, Satoru Kobayashi, Mizuho Kobayashi, Shinji Saitoh, Haruo Goto   +5 more
doaj   +1 more source

Prolonged Fetal Bradycardia as the Presenting Clinical Sign in Congenital Syphilis Complicated by Necrotizing Funisitis: A Case Report [PDF]

, 2011
Syphilis remains a serious cause of neonatal morbidity and mortality worldwide. In this paper, we describe a case of congenital syphilis that was fully supported by abnormal fetal heart rate patterns and placental histopathological evidence.
Shigeki Minoura, Kazuhusa Hoshimoto, Hideto Gomibuchi, Jun Kakogawa, Norio Masuya, Miyuki Sadatsuki   +5 more
core   +1 more source