Results 131 to 140 of about 81,937 (315)
ABSTRACT Background Mixed gonadal dysgenesis (MGD) is a rare form of differences in sex development (DSD) typically associated with 45,X/46,XY mosaicism. The phenotypic presentation of MGD varies from atypical genitalia to typical male or female appearances often associated with Turner stigmata.
Dinesh Giri +6 more
wiley +1 more source
Molecular profile of atypical Leydig cell tumours
Copy number variations by themselves are not sufficient to discriminate between benign and potential malignant Leydig cell tumours (LCTs). Genomic instability was only detected in malignant and atypical cases, and not in any benign tumours. Currently, the presence of metastasis remains the only malignant criterion for LCTs.
Muhammad F.K. Choudhry +6 more
wiley +1 more source
hnRNPU Safeguards Oocyte Development and Female Fertility via Regulation of Alternative Splicing
Heterogeneous nuclear ribonucleoprotein U (hnRNPU) is essential for oocyte development and female fertility. Oocyte‐specific deletion of Hnrnpu leads to follicular arrest, impaired meiotic maturation, mitochondrial dysfunction, and infertility.
Jinmei Li +8 more
wiley +1 more source
Proteomic Signatures Over Age Reveal Significant Changes From Infancy Till Late Adulthood
Age‐specific changes in the serum proteome were investigated across the entire lifespan, from infancy till late adulthood by analyzing 178 proteins in serum samples of healthy individuals. Using various analyses approaches, distinct protein expression profiles and four protein patterns during aging were identified.
Eveline M. Delemarre +11 more
wiley +1 more source
The Impact of Inherited Thrombophilia on First Trimester Combined Aneuploidy Screening Parameters
Objective. To investigate the impact of thrombophilia on pregnancy-associated plasma protein A (PAPP-A) and human chorionic gonadotropin (hCG) and the nuchal translucency (NT) during the first trimester of the pregnancy.
Kirovakov Z., Hinkova N., Konova E.
doaj +1 more source
This review examines the use of fluorescent nanodiamonds (FNDs) in lateral flow assays (LFAs) for advanced diagnostics. FNDs offer superior photostability and biocompatibility compared to traditional labels. The review covers FND synthesis, and integration with detection systems to enhance performance.
Jihoon Shin +10 more
wiley +1 more source
Submyomatous Cornual Pregnancy : Managed surgically after failed medical management
Cornual pregnancy constitutes an emergency while its diagnosis and management remain a challenge. Anatomical abnormalities in the uterus, such as fibroids in the cornual region, make the management even more difficult.
Lamya Al-Kharusi +4 more
doaj

