Results 131 to 140 of about 81,937 (315)

Mixed Gonadal Dysgenesis: A Comprehensive Review of Clinical Spectrum, Diagnostic Strategies, and Management Approaches

open access: yesClinical Endocrinology, Volume 104, Issue 2, Page 92-102, February 2026.
ABSTRACT Background Mixed gonadal dysgenesis (MGD) is a rare form of differences in sex development (DSD) typically associated with 45,X/46,XY mosaicism. The phenotypic presentation of MGD varies from atypical genitalia to typical male or female appearances often associated with Turner stigmata.
Dinesh Giri   +6 more
wiley   +1 more source

Molecular profile of atypical Leydig cell tumours

open access: yesHistopathology, Volume 88, Issue 3, Page 628-635, February 2026.
Copy number variations by themselves are not sufficient to discriminate between benign and potential malignant Leydig cell tumours (LCTs). Genomic instability was only detected in malignant and atypical cases, and not in any benign tumours. Currently, the presence of metastasis remains the only malignant criterion for LCTs.
Muhammad F.K. Choudhry   +6 more
wiley   +1 more source

hnRNPU Safeguards Oocyte Development and Female Fertility via Regulation of Alternative Splicing

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Heterogeneous nuclear ribonucleoprotein U (hnRNPU) is essential for oocyte development and female fertility. Oocyte‐specific deletion of Hnrnpu leads to follicular arrest, impaired meiotic maturation, mitochondrial dysfunction, and infertility.
Jinmei Li   +8 more
wiley   +1 more source

Proteomic Signatures Over Age Reveal Significant Changes From Infancy Till Late Adulthood

open access: yesAdvanced Biology, Volume 10, Issue 1, January 2026.
Age‐specific changes in the serum proteome were investigated across the entire lifespan, from infancy till late adulthood by analyzing 178 proteins in serum samples of healthy individuals. Using various analyses approaches, distinct protein expression profiles and four protein patterns during aging were identified.
Eveline M. Delemarre   +11 more
wiley   +1 more source

The Impact of Inherited Thrombophilia on First Trimester Combined Aneuploidy Screening Parameters

open access: yesActa Medica Bulgarica
Objective. To investigate the impact of thrombophilia on pregnancy-associated plasma protein A (PAPP-A) and human chorionic gonadotropin (hCG) and the nuchal translucency (NT) during the first trimester of the pregnancy.
Kirovakov Z., Hinkova N., Konova E.
doaj   +1 more source

Fluorescent Nanodiamonds for Lateral Flow Assays Enhanced by Magnetic Modulation: From Synthesis to Application

open access: yesAdvanced Energy and Sustainability Research, Volume 7, Issue 1, January 2026.
This review examines the use of fluorescent nanodiamonds (FNDs) in lateral flow assays (LFAs) for advanced diagnostics. FNDs offer superior photostability and biocompatibility compared to traditional labels. The review covers FND synthesis, and integration with detection systems to enhance performance.
Jihoon Shin   +10 more
wiley   +1 more source

Submyomatous Cornual Pregnancy : Managed surgically after failed medical management

open access: yesSultan Qaboos University Medical Journal, 2011
Cornual pregnancy constitutes an emergency while its diagnosis and management remain a challenge. Anatomical abnormalities in the uterus, such as fibroids in the cornual region, make the management even more difficult.
Lamya Al-Kharusi   +4 more
doaj  

Home - About - Disclaimer - Privacy