Results 11 to 20 of about 2,740 (178)

Evaluating the Utility of RNAseq in Prenatal Diagnostics: Expression Profiles of Cultured Chorionic Villus and Amniotic Fluid Samples. [PDF]

Prenat Diagn
ABSTRACT Objective While RNAseq has enhanced variant interpretation in postnatal cases, its potential in the prenatal setting remains underexplored. This study investigates the utility of RNAseq in prenatal diagnostics by analyzing the expression profiles of cultured chorionic villus samples (cCVS) and amniotic fluid (cAF) samples. Methods We performed
Vladoiu MC, Zhao S, Zemet R, Parobek CM, Sinson JC, Tankersley S, Van den Veyver IB, Liu P.   +7 more
europepmc   +2 more sources

Pregnancy Outcome of Chorionic Villus Sampling on 260 Couples with Beta- Thalassemia Trait in North of Iran [PDF]

Acta Medica Iranica, 2010
"nChorionic villus sampling (CVS) is a new method and its true risk of fetal loss and complications is not still clearly determined. The objective of this study was to review the clinical pregnancy outcome of transabdominal CVS (TA-CVS) performed on
Nesa Asnafi, Haleh Akhavan Niaki
doaj   +2 more sources

Normal postnatal outcome in an r(X) mosaic male fetus with retained XIST gene

Journal of Pediatric and Neonatal Individualized Medicine, 2020
We report the case of a pregnant woman who underwent prenatal diagnosis by chorionic villi sampling for increased risk of trisomy 21 due to advanced age and abnormal results of the first trimester combined screening test.
Maura Mingoia, Francesca Sessini, Daniela Gasperini, Paolo Moi   +3 more
doaj   +1 more source

Adequate Placental Sampling for the Diagnosis and Characterization of Placental Infection by Zika Virus

Frontiers in Microbiology, 2020
The detection of Zika virus (ZIKV) in immunoprivileged anatomical sites, potential sites for viral persistence, may guide the confirmation of undefined cases of ZIKV infection and also bring to light unknown pathways of viral transmission.
Emanuella Meneses Venceslau, José Paulo Siqueira Guida, Guilherme de Moraes Nobrega, Ana Paula Samogim, Pierina Lorencini Parise, Rodolfo Rosa Japecanga, Daniel Augusto de Toledo-Teixeira, Julia Forato, Arthur Antolini-Tavares, Arethusa Souza, Albina Altemani, Silvio Roberto Consonni, Renato Passini, Eliana Amaral, Jose Luiz Proenca-Modena, Maria Laura Costa, The Zika-Unicamp Network, John D. Horowitz, Glaucia Maria Pastore, Helaine Maria Besteti Pires Mayer-Milanez, Carolina C. Ribeiro-do-Valle, Roseli Calil, João Renato Bennini Junior, Giuliane Jesus Lajos, Maria Luiza Moretti, Mariangela Ribeiro Resende, Márcia Teixeira Garcia, Rodrigo Nogueira Angerami, Kleber Yotsumoto Fertrin, Marcos Tadeu Nolasco da Silva, Ana Carolina Coan, Santos Maria Francisca Colella, Andrea Paula Bruno von Zuben, André Ricardo Ribas Freitas, Marco Aurélio Ramirez Vinolo, Rodrigo Ramos Catharino, Fábio Trindade Maranhão Costa, Clarice Weis Arns, Matheus Martini, é vellyn Ribeiro de Morais   +39 more
doaj   +1 more source

Hepatosplenomegaly Associated with Transient Abnormal Myelopoiesis in Down Syndrome: An Autopsy Case of a Stillborn Fetus

Case Reports in Oncology, 2015
A 38-year-old primiparous mother (gravida 1, para 0) at 27 weeks and 6 days' gestation reported that fetal movements had been absent for 6 days. All serological markers for infection were negative.
Michiko Yuki, Yuko Emoto, Yuichi Kinoshita, Katsuhiko Yoshizawa, Takashi Yuri, Airo Tsubura   +5 more
doaj   +1 more source

Examination and Sampling of Chorionic Villi for the Diagnosis of Beta-Thalassemia Major in the First Trimester of Pregnancy in Southwestern Iran

Armaghane Danesh Bimonthly Journal, 2022
Background & aim: Beta thalassemia is one of the most common hereditary diseases in Iran. The birth of a child with thalassemia causes many social and economic problems for parents and the health care system.
E Shams, M AllahDadian, Z Yadegari Baharanchi, M Harfsheno   +3 more
doaj  

A decade of change – lessons learned from prenatal diagnostics in Central Denmark region in 2008–2018

Acta Obstetricia et Gynecologica Scandinavica, 2023
Introduction In 2011, it was decided to implement chromosomal microarray in prenatal testing in the Central Denmark Region, mainly due to the expected higher diagnostic yield.
Dorte Launholt Lildballe, Naja Becher, Else Marie Vestergaard, Rikke Christensen, Stina Lou, Puk Sandager, Lars Henning Pedersen, Kasper Gadsbøll, Olav Bjørn Petersen, Ida Vogel   +9 more
doaj   +1 more source

When NIPT meets WES, prenatal diagnosticians face the dilemma: genetic etiological analysis of 2,328 cases of NT thickening and follow-up of pregnancy outcomes

Frontiers in Genetics, 2023
Objective: To assess the performance of diverse prenatal diagnostic approaches for nuchal translucency (NT) thickening and to investigate the optimal prenatal screening or diagnostic action with a NT thickening of 95th percentile-3.50 mm.Methods: A ...
Xueqi Ji, Xueqi Ji, Qiongmei Li, Qiongmei Li, Yiming Qi, Yiming Qi, Yiming Qi, Xingwang Wang, Xingwang Wang, Xingwang Wang, Hongke Ding, Hongke Ding, Hongke Ding, Jian Lu, Jian Lu, Jian Lu, Yan Zhang, Yan Zhang, Yan Zhang, Aihua Yin, Aihua Yin, Aihua Yin   +21 more
doaj   +1 more source

Influence of advanced maternal age and gestational age on the morphology of human placenta [PDF]

Scripta Medica
Background/Aim: The placenta is an extraembryonic organ necessary for foetal development. Due to its availability and high content of stem cells and growth factors, placenta tissue has found its application in regenerative medicine. The aim of this paper
Jovičić Sanja, Ljubojević Vesna, Barudžija Maja, Amidžić Ljiljana, Škrbić Ranko, Nikolić Ivan R.   +5 more
doaj   +1 more source

Abortion for Fetal Genetic Abnormalities: Type of Abnormality and Gestational Age at Diagnosis

American Journal of Perinatology Reports, 2020
Background Advances in genetic screening can identify patients at high risk for common genetic conditions early in pregnancy and can facilitate early diagnosis and early abortion. Less common abnormalities might only be diagnosed with invasive testing is
Tracy B. Grossman, Stephen T. Chasen
doaj   +1 more source