Frontiers in Genetics, 2023 Objective: To assess the performance of diverse prenatal diagnostic approaches for nuchal translucency (NT) thickening and to investigate the optimal prenatal screening or diagnostic action with a NT thickening of 95th percentile-3.50 mm.Methods: A ...
Xueqi Ji +21 more
doaj +1 more source
Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface [PDF]
, 2009 Plasma concentrations of biologically active vitamin D (1,25- (OH)2D) are tightly controlled via feedback regulation of renal 1-hydroxylase (CYP27B1; positive) and 24-hydroxylase (CYP24A1; catabolic) enzymes.
Albertson +101 more
core +3 more sources
Influence of advanced maternal age and gestational age on the morphology of human placenta [PDF]
Scripta MedicaBackground/Aim: The placenta is an extraembryonic organ necessary for foetal development. Due to its availability and high content of stem cells and growth factors, placenta tissue has found its application in regenerative medicine. The aim of this paper
Jovičić Sanja +5 more
doaj +1 more source
Abortion for Fetal Genetic Abnormalities: Type of Abnormality and Gestational Age at Diagnosis
American Journal of Perinatology Reports, 2020 Background Advances in genetic screening can identify patients at high risk for common genetic conditions early in pregnancy and can facilitate early diagnosis and early abortion. Less common abnormalities might only be diagnosed with invasive testing is
Tracy B. Grossman, Stephen T. Chasen
doaj +1 more source
Altered fetal growth, placental abnormalities, and stillbirth. [PDF]
PLoS ONE, 2017 Worldwide, stillbirth is one of the leading causes of death. Altered fetal growth and placental abnormalities are the strongest and most prevalent known risk factors for stillbirth.
Radek Bukowski +16 more
doaj +1 more source
Hypoxic Preconditioning Enhances Survival and Proangiogenic Capacity of Human First Trimester Chorionic Villus-Derived Mesenchymal Stem Cells for Fetal Tissue Engineering. [PDF]
, 2019 Prenatal stem cell-based regenerative therapies have progressed substantially and have been demonstrated as effective treatment options for fetal diseases that were previously deemed untreatable. Due to immunoregulatory properties, self-renewal capacity,
Farmer, Diana L +7 more
core +1 more source
Taiwanese Journal of Obstetrics & Gynecology, 2020 Objective: We present detection of paternal origin of fetal trisomy 18 in a pregnancy conceived by assisted reproductive technology (ART) and in vitro fertilization (IVF).
Chih-Ping Chen +6 more
doaj +1 more source
Slow Fetal Heart Rate before Miscarriage in the Early First Trimester Predicts Fetal Aneuploidy in Women with Recurrent Pregnancy Loss [PDF]
, 2018 Establishing whether miscarriages result from fetal aneuploidy or other factors is important for treating recurrent pregnancy loss. We examined the relationship between fetal heart rate (FHR) before miscarriage in the early first trimester and fetal ...
Hasegawa, Toru +6 more
core +1 more source
Generation of Trophoblast Organoids from Chorionic Villus Sampling
OrganoidsStudying human placental development and function presents significant challenges due to the inherent difficulties in obtaining and maintaining placental tissue throughout the course of an ongoing pregnancy.
Bas van Rijn +5 more
doaj +1 more source
Taiwanese Journal of Obstetrics & Gynecology, 2017 Objective: We present the application of non-invasive prenatal testing (NIPT) in late gestation in a pregnancy associated with intrauterine growth restriction (IUGR) and trisomy 22 confined placental mosaicism (CPM).
Chih-Ping Chen +8 more
doaj +1 more source