Results 61 to 70 of about 2,656 (193)

A Situational Overview of Prenatal Screening Services in Bhutan

Public Health Challenges
Prenatal genetic testing is to determine the possibility of the fetus having a genetic aberration or birth defect. Prenatal screening consists of serum analytes screening with or without nuchal translucency (NT) scanning or with cell‐free DNA (CfDNA ...
Yeshey Dorjey, Tashi Gyeltshen, Thinley Dorji, Don Eliseo Lucero‐Prisno III, Mimi Lhamu Mynak, Sonam Gyamtsho, Tashi Tshomo, Phurb Dorji   +7 more
doaj   +1 more source

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

The FEBS Journal, EarlyView.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo, Lorenza Driul, Vanessa Tolotto, Eros Di Giorgio, Luigi E. Xodo   +4 more
wiley   +1 more source

Endothelial‐to‐mesenchymal transition in the fetoplacental macrovasculature and microvasculature in pregnancies complicated by gestational diabetes

The Journal of Physiology, EarlyView.
Abstract figure legend Transforming growth factor (TGF)‐β2 and interleukin (IL)‐1β induced morphological and molecular changes consistent with endothelial‐to‐mesenchymal transition (EndMT) in HUVECs isolated from both pregnancies complicated by gestational diabetes (GDM) and non‐GDM pregnancies.
Abigail R. Byford, Georgia Fakonti, Ziyu Shao, Sharanam Soni, Sophie L. Earle, Muath Bajarwan, Lara C. Morley, Beth Holder, Eleanor M. Scott, Karen Forbes   +9 more
wiley   +1 more source

Placental biomarkers of phthalate effects on mRNA transcription: application in epidemiologic research

Environmental Health, 2009
Background CYP19 and PPARγ are two genes expressed in the placental trophoblast that are important to placental function and are disrupted by phthalate exposure in other cell types.
Nelson Heather, Thaker Harshwardhan M, Whyatt Robin M, Williams Paige L, Hauser Russ, Adibi Jennifer J, Herrick Robert, Bhat Hari K   +7 more
doaj   +1 more source

High‐elevation adaptation and gestational hypoxia jointly shape vascular development in a rodent placenta

The Journal of Physiology, EarlyView.
Abstract figure legend We investigated how environmental hypoxia and genetic adaptation to high altitudes jointly impact the development of the placental exchange surface in ways that might protect fetal growth potential. We used wild‐derived, lab‐born North American deer mice (Peromyscus maniculatus) from low‐elevation and high‐elevation environments (
Kathryn Wilsterman, Zachary A. Cheviron, Jeffrey M. Good, Kai Gurnoe‐Brantley, Kylie E. Jewett, Katherine Kiel, Ashley M. Larson   +6 more
wiley   +1 more source

Maternal Parvovirus B19 Infection Causing First-Trimester Increased Nuchal Translucency and Fetal Hydrops

Case Reports in Obstetrics and Gynecology, 2019
This is a case report of a 31-year-old primigravida who was diagnosed with an asymptomatic acute parvovirus B19 infection in the second trimester of pregnancy and its suspected association with an increased nuchal translucency (NT) measurement ...
Olivia Grubman, Farrah Naz Hussain, Zoe Nelson, Lois Brustman   +3 more
doaj   +1 more source

A review of trisomy X (47,XXX)

Orphanet Journal of Rare Diseases, 2010
Trisomy X is a sex chromosome anomaly with a variable phenotype caused by the presence of an extra X chromosome in females (47,XXX instead of 46,XX).
Sutherland Ashley, Howell Susan, Tartaglia Nicole R, Wilson Rebecca, Wilson Lennie   +4 more
doaj   +1 more source

A primary cell‐based fluidic co‐culture model to investigate drug transport across the human placenta

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of a flow‐driven in vitro model of the human placental barrier designed to study transport processes during pregnancy. The model recreates key features of the maternal–fetal interface, enabling the investigation of how nutrients and therapeutic compounds cross the placental barrier under physiologically ...
Barbara Fuenzalida, Nadja Koechli, Edgar Ontsouka, Chennakesava Cuddapah, Martin Mueller, Bram Sengers, Frantisek Staud, Christiane Albrecht   +7 more
wiley   +1 more source

Os macrófagos na placenta durante o trabalho de parto The macrophages in the placenta during labor

Revista Brasileira de Ginecologia e Obstetrícia, 2009
OBJETIVO: verificar a quantidade de células CD68+ no estroma das vilosidades coriônicas na placenta de gestações submetidas ou não ao trabalho de parto. MÉTODOS: estudo transversal, com gestantes saudáveis a termo, das quais 31 placentas foram examinadas
Júlio Augusto Gurgel Alves, Lilia Maria Carneiro Câmara, Fabrício da Silva Costa, Rebeca Silveira Rocha, Maria Neile Torres de Araújo   +4 more
doaj   +1 more source

Caesarean Scar Ectopic Pregnancy in Early Gestation: A Scoping Review of Definitions and Diagnostic Approach

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 5, Page 888-899, April 2026.
ABSTRACT Background Caesarean scar ectopic pregnancy (CSEP) is defined by the implantation and development of a gestational sac inside a caesarean scar defect, but variations in classification systems and diagnostic criteria exist. Objectives This study aimed to systematically review the different criteria used in the medical literature to diagnose ...
Simrit Nijjar, Lucrezia V. De Braud, Ewelina Rogozińska, Cecilia Bottomley, Davor Jurkovic, Eric Jauniaux   +5 more
wiley   +1 more source